DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rsph1 and jph2

DIOPT Version :9

Sequence 1:	NP_609609.1	Gene:	Rsph1 / 34712	FlyBaseID:	FBgn0032478	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001082833.1	Gene:	jph2 / 553333	ZFINID:	ZDB-GENE-030131-9848	Length:	781	Species:	Danio rerio

Alignment Length:	344	Identity:	77/344 - (22%)
Similarity:	123/344 - (35%)	Gaps:	106/344 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GLYIGGRNAAGQRQGRG--------------------------WAILPNGDQYDGNYRKGRRHGI 63
            |.|.||.. .|:..|.|                          |   |:|:.|:|.:.:|:|||:
Zfish    12 GAYCGGWE-GGKAHGHGICTGPKGQGEFSGSWNYGFEVVGVYTW---PSGNTYEGYWSQGKRHGL 72

  Fly    64 GV-----YVFKDGSRYYGQYRCGKRCGRGIFIYPDGSVYEGNWRKNLKHGKGRYKYVNGDNYSGD 123
            ||     :::|....:..:.|.|.|..:|     .|:.|||.|...|:.|.|...|.:|..:.|.
Zfish    73 GVETKGHWIYKGEWTHGFKGRYGTRISQG-----SGAKYEGTWNNGLQDGYGTETYADGGTFQGQ 132

  Fly   124 WFKGQRHGVGIYHFNSGKDGCCLSVRMKATWNSNMRTGPFELYIGNEDKCTILHGIWDNLYPSGP 188
            :..|.|||.|:..        .:...|.|..:|.:|.....|...:.:...:...:        |
Zfish   133 FTGGMRHGYGVRQ--------SVPYGMAAVVHSPLRNSLSSLRSEHSNGTLLQQDV--------P 181

  Fly   189 AVFSFNNRYLLLGYFLPASYNMKAISNEDEMEDAEERLEDEMGEAEPMEPTL-WFAQEMAVYDFS 252
            .:.:.|    ..|...|.:..|                        |:.|:. .||..:.|...:
Zfish   182 VITTTN----ASGQETPVNLPM------------------------PLGPSRGGFALTLQVDPDA 218

  Fly   253 LLPQEP---------VPLAISDSELSVCSLSTEPS-MRSEEKISWYGEGE-------EAEGEEGG 300
            :.|::.         ..|..|||..|:.|..::.| :|:|..:|......       |:|||  |
Zfish   219 VKPKKSGLFRRGSFLGKLKKSDSRTSLSSQKSKISFLRTESALSSAASDANSTISLGESEGE--G 281

  Fly   301 EMECF-PCECDLTDVSEVE 318
            |...| |.|.|: |.:..|
Zfish   282 EGHNFPPVEADI-DATTTE 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rsph1	NP_609609.1	MORN	51..73	CDD:280628	9/26 (35%)
		MORN	72..93	CDD:197832	4/20 (20%)
		MORN	95..116	CDD:197832	8/20 (40%)
		MORN	118..137	CDD:197832	6/18 (33%)
jph2	NP_001082833.1	MORN	106..128	CDD:280628	9/21 (43%)
		MORN	324..346	CDD:280628
		TonB_N	605..757	CDD:292650
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900