DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rsph1 and Als2cl

DIOPT Version :9

Sequence 1:	NP_609609.1	Gene:	Rsph1 / 34712	FlyBaseID:	FBgn0032478	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	XP_006244073.1	Gene:	Als2cl / 316017	RGDID:	1305208	Length:	952	Species:	Rattus norvegicus

Alignment Length:	216	Identity:	52/216 - (24%)
Similarity:	80/216 - (37%)	Gaps:	60/216 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GRNAAGQRQGRGWAILPNGDQYDGNYRKGRRHGIGVYVFKDGSR-YYGQYRC----GKRCGRGIF 89
            |..:..:..|:|....|:|..:.|::.:|..||.|:.:....|. .:..|:|    |:.|..||.
  Rat   360 GEWSRAKPHGKGTLKWPDGRNHVGDFYQGLEHGFGICLVPQASEDKFDCYKCHWREGRMCEYGIC 424

  Fly    90 IYPDGSVYEGNWRKNLKHGKG----------RYKYV------------------NGDNYSGDWFK 126
            .|....||:|.::..::||.|          .::|.                  .|:.|.|.|..
  Rat   425 EYGTDEVYKGYFQAGVRHGFGVLDSAPQAPQPFRYTGHWERGQRSGYGIEEDRDRGERYIGMWQA 489

  Fly   127 GQRHGVGIYHFNSGKDGCCLSVRMKATWNSNMRTGPFELYIGNEDKCTILHGIWDNLYPS----- 186
            .||||.||....:|       |..:.|:..:...||..|..  ||         |:||..
  Rat   490 DQRHGPGIVVTQAG-------VCYQGTFQGDKMAGPGILLC--ED---------DSLYEGTFTRE 536

  Fly   187 ----GPAVFSFNNRYLLLGYF 203
                |....:|.|.:.|.|.|
  Rat   537 LTLLGKGKVTFPNGFTLEGSF 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rsph1	NP_609609.1	MORN	51..73	CDD:280628	5/21 (24%)
		MORN	72..93	CDD:197832	8/25 (32%)
		MORN	95..116	CDD:197832	7/48 (15%)
		MORN	118..137	CDD:197832	9/18 (50%)
Als2cl	XP_006244073.1	PH-like	223..321	CDD:418428
		PLN03185	357..>550	CDD:215619	48/207 (23%)
		VPS9	835..937	CDD:388595
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900