DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rsph1 and MORN3

DIOPT Version :9

Sequence 1:	NP_609609.1	Gene:	Rsph1 / 34712	FlyBaseID:	FBgn0032478	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001350614.1	Gene:	MORN3 / 283385	HGNCID:	29807	Length:	240	Species:	Homo sapiens

Alignment Length:	271	Identity:	63/271 - (23%)
Similarity:	91/271 - (33%)	Gaps:	90/271 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PEEEEDLGPNIGLYIGGRNAAGQRQG-RGWAILPNGDQYDGNYRKGRRHGIGVYVF-KDGSRYYG 76
            |::.|.|..       |.:...||.| |......|||.|.|.::...:||.|..|: |.|:.|.|
Human     7 PKKSESLWK-------GWDRKAQRNGLRSQVYAVNGDYYVGEWKDNVKHGKGTQVWKKKGAIYEG 64

  Fly    77 QYRCGKRCGRGIFIYPDGSV-----------------------------YEGNWRKNLKHGKGRY 112
            .::.|||.|.|....||...                             |||:|..:.:.|.||.
Human    65 DWKFGKRDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRM 129

  Fly   113 KYVNGDNYSGDWFKGQRHGVGIYHFNSGK--DGCCLSVRMKATWNSNMRTGPFELYIGNEDKCTI 175
            .|.|||.|.|.|...:.:|.|:....:|.  :||         |...|:.|....:  :.|...:
Human   130 YYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGC---------WERGMKNGAGRFF--HLDHGQL 183

  Fly   176 LHGIW-DNLYPSGPAVFSFNNRYLLLGYFLPASYNMKAISNEDEMEDAEERLEDEMGEAEPMEPT 239
            ..|.| ||:...|..:                                      :.|..|..|||
Human   184 FEGFWVDNMAKCGTMI--------------------------------------DFGRDEAPEPT 210

  Fly   240 LWFAQEMAVYD 250
            .:...|:.:.|
Human   211 QFPIPEVKILD 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rsph1	NP_609609.1	MORN	51..73	CDD:280628	8/22 (36%)
		MORN	72..93	CDD:197832	7/20 (35%)
		MORN	95..116	CDD:197832	8/49 (16%)
		MORN	118..137	CDD:197832	6/18 (33%)
MORN3	NP_001350614.1	COG4642	34..>188	CDD:332236	44/164 (27%)
		MORN 1	38..60		7/21 (33%)
		MORN 2	62..84		9/21 (43%)
		MORN 3	91..113		0/21 (0%)
		MORN 4	114..136		10/21 (48%)
		MORN 5	137..159		6/21 (29%)
		MORN 6	160..182		6/32 (19%)
		MORN 7	184..205		6/58 (10%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1309439at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910