DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5287 and dpagt1

DIOPT Version :9

Sequence 1:	NP_609608.1	Gene:	CG5287 / 34711	FlyBaseID:	FBgn0032477	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001082880.1	Gene:	dpagt1 / 566539	ZFINID:	ZDB-GENE-060526-18	Length:	406	Species:	Danio rerio

Alignment Length:	406	Identity:	229/406 - (56%)
Similarity:	293/406 - (72%)	Gaps:	11/406 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VAIAINAAISGAAYCMTVRMIPRFREMFIKANLFGNDLCKKDKPQVPESFGVLIGCVFLVSLFLF 68
            |.:.||..:|......||::||.|:|.||.|.|:|.||.|..|.:||||.||:.|.|||:.||||
Zfish     7 VPLIINCCMSALGCIATVKLIPAFKEHFISARLYGMDLNKTTKKEVPESQGVISGTVFLIILFLF 71

  Fly    69 IPIPFAFDEAAATDAITGGKPDTFPHDKFVELIAALLSICCMIFLGFADDVLDLRWRHKLLLPTI 133
            ||:||       .....|.|...|||::||:||.|||:||||||||||||||:|||||||||||:
Zfish    72 IPVPF-------LQCFMGEKCQRFPHNEFVQLIGALLAICCMIFLGFADDVLNLRWRHKLLLPTM 129

  Fly   134 ATLPLLMVYYVNYNSTTVIMPNFARNLIGTSLNIGALYYVFMGMLAVFCTNAINILAGINGLEVG 198
            |:|||||||:.|:.:|.:::|...|.|:|..|::|.||||:||||||||||||||||||||:|.|
Zfish   130 ASLPLLMVYFTNFGNTVIVVPKPFRLLLGMHLDLGILYYVYMGMLAVFCTNAINILAGINGIESG 194

  Fly   199 QSFIIAGSILVFNAIELLLGHQVDSHIFSIYFMLPFLATTLALWKFNKYPSQVFVGDTYCYFAGM 263
            |:..|:|||::||.:| |.|...|.|:||:|||:||..|||||:..|.|||.||||||:||||||
Zfish   195 QALFISGSIILFNLLE-LNGDYRDDHVFSLYFMIPFFFTTLALFYHNWYPSSVFVGDTFCYFAGM 258

  Fly   264 TFAVVGILGHFSKTLLLFFLPQILNFLYSTPQLFHFVPCPRHRLPKYDSKTDLLHISTTEFRLED 328
            ||||||||||||||:||||:||::||:||.|||||.:||||||||:..|.|..|.:|.::|:.:|
Zfish   259 TFAVVGILGHFSKTMLLFFIPQVINFIYSLPQLFHIIPCPRHRLPRLQSDTGKLGMSYSKFKQKD 323

  Fly   329 LNAPGRLMVTVLRNLRLISWHTKADG---VVRTNNFTLINFVLVVFGPVHERVVTQMLMGFQVLC 390
            |...|:|::.|...|.::......:|   .:..||.||||.||.:.||.|||.:|.:::..|||.
Zfish   324 LGKLGQLILKVAEKLWVLDVRRGQEGDDEFIECNNMTLINLVLKILGPTHERTLTAIMLLMQVLG 388

  Fly   391 TLIALTIRYPLANYFY 406
            :.:|..|||.|...||
Zfish   389 SAVAFGIRYHLVRLFY 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5287	NP_609608.1	GT_GPT_euk	24..320	CDD:133465	190/295 (64%)
dpagt1	NP_001082880.1	GT_GPT_euk	27..315	CDD:133465	190/295 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577550
Domainoid	1	1.000	250	1.000	Domainoid score	I2076
eggNOG	1	0.900	-	-		E1_COG0472
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1058
Inparanoid	1	1.050	458	1.000	Inparanoid score	I1553
OMA	1	1.010	-	-		QHG53672
OrthoDB	1	1.010	-	-		D1079130at2759
OrthoFinder	1	1.000	-	-		FOG0004088
OrthoInspector	1	1.000	-	-		oto38894
orthoMCL	1	0.900	-	-		OOG6_101483
Panther	1	1.100	-	-	LDO	PTHR10571
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R522
SonicParanoid	1	1.000	-	-		X2836
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800