Protein Alignment CG5439 and SNX29

DIOPT Version :9

• Sequence 1: NP_609607.1
• Gene: CG5439 / 34710
• FlyBaseID: FBgn0032476
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_011521040.1
• Gene: SNX29 / 92017
• HGNCID: 30542
• Length: 879
• Species: Homo sapiens
• Alignment Length: 821
• Identity: 173/821 - (21%)
• Similarity: 275/821 - (33%)
• Gaps: 341/821 - (41%)

  Fly    24 GSTFGQRREDIFRRLQESAHKISQKFSG-KELATERDESVQELCESLEELMSYGLRQSAGTSSFS 87
            ||....:|:.:..||.::..:...:|.| ||:|::.|..|..||...|.::.:||::|.|.:..:
Human    13 GSQNNDKRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLKRSRGLALTA 77

  Fly    88 AASFIQNMQEMVSGNAGGGS-NNNDATFWEFCQTHLTPHERQRYMDLKQIWTNVGRGRAFIRATL 151
            ||         :...||..| ...:..||.:.:..|..||.||:..|:.|.::||||||::|..|
Human    78 AA---------IKQAAGFASKTETEPVFWYYVKEVLNKHELQRFYSLRHIASDVGRGRAWLRCAL 133

  Fly   152 NEKRLHSHVLTWLSDEEQLHRFYTPWSLLLNDEAAKKLPEIVDSLSDVLFALNVDTTELNAPRRS 216
            ||..|..::...|:|..:|..||..||.::::|.:..||.:...|:.:|||:|:|..:||...:.
Human   134 NEHSLERYLHMLLADRCRLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKF 198

  Fly   217 TPSVA--VKEEPIIFT--------------------------------TSPVPVVGR-------- 239
            .|:|:  :||.....|                                |.|:|||.|
Human   199 APTVSDLLKESTQNVTSLLKESTQGVSSLFREITASSAVSILIKPEQETDPLPVVSRNVSADAKC 263

  Fly   240 -----------------------------QKRPGIAVERPIECVSSTEDLLGALK---------- 265
                                         :|.||...........|:.:::.|.:
Human   264 KKERKKKKKVTNIISFDDEEDEQNSGDVFKKTPGAGESSEDNSDRSSVNIMSAFESPFGPNSNGS 328

  Fly   266 ------PIESVEVQ-----QILSKESIEQELAQPQEE---------------------------- 291
                  .|:|:.:.     |.|..:||:.|.....|:
Human   329 QSSNSWKIDSLSLNGEFGYQKLDVKSIDDEDVDENEDDVYGNSSGRKHRGHSESPEKPLEGNTCL 393

  Fly   292 ----------------------VNLGPFDPIEPELEFLKT-------PLPDIG------------ 315
                                  ..:|.:.|.:..|..|:.       .|||.|
Human   394 SQMHSWAPLKVLHNDSDILFPVSGVGSYSPADAPLGSLENGTGPEDHVLPDPGLRYSVEASSPGH 458

  Fly   316 ----------AHVGE----SELYE------DRSDTSSQWSKSSSSANCL-ANSQQQAALEEHVNQ 359
                      |.|.|    |||.:      :|.|...:  ::.|..|.| ...:..|||.:.|:.
Human   459 GSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEE--ENRSLRNLLDGEMEHSAALRQEVDT 521

  Fly   360 LNERCALLETR----VAELSLQNRLLIRRLTK--------------------------------- 387
            |..:.|..|.|    |..|:.:|.:|..:|.|
Human   522 LKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVPNLWSVDGEVTVAEQK 586

  Fly   388 ---------------------------QFEE---------------------------------T 392
                                       :|.|                                 |
Human   587 PGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQT 651

  Fly   393 GIDPSSS---LCSNFLIT--IPHVKLAKTQRSGSHYTYEVHITMRQRLEHWTFFRRYSEFYKLHK 452
            ..|.|.|   :.:..||.  ||.|.| :.:.:.:.:.|:|:|.::.  :.|..:|||:||..||.
Human   652 SEDQSLSDFEISNRALINVWIPSVFL-RGKAANAFHVYQVYIRIKD--DEWNIYRRYTEFRSLHH 713

  Fly   453 SLLKTHPVVSAVEFPPKKHFGN-------------------------MNL------------VFV 480
            .|...:|.|.|..|||||..||                         :||            .||
Human   714 KLQNKYPQVRAYNFPPKKAIGNKPPPSPAWMTAAASLLASLLPALPPLNLQVTSEVTSSQDAKFV 778

  Fly   481 EERRQQLQIYLLN----LVETLPQVEACKSKAELQKVFPFF 517
            ||||:|||.||.:    :::.:|:..|...|..|.::.|||
Human   779 EERRKQLQNYLRSVMNKVIQMVPEFAASPKKETLIQLMPFF 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	64..206	CDD:280855	47/142 (33%)
		PX_RUN	404..520	CDD:132810	48/157 (31%)
SNX29	XP_011521040.1	RUN	54..189	CDD:280855	47/143 (33%)
		Ax_dynein_light	<487..552	CDD:287215	17/66 (26%)
		PX_RUN	668..820	CDD:132810	47/155 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	90	1.000	Domainoid score	I7816
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250381at33208
OrthoFinder	1	1.000	-	-		FOG0006133
OrthoInspector	1	1.000	-	-		oto88821
orthoMCL	1	0.900	-	-		OOG6_107516
Panther	1	1.100	-	-	LDO	PTHR47194
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5491
SonicParanoid	1	1.000	-	-		X5870
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.850