Protein Alignment CG5439 and MDM1

DIOPT Version :10

• Sequence 1: NP_609607.1
• Gene: CG5439 / 34710
• FlyBaseID: FBgn0032476
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_013603.1
• Gene: MDM1 / 854867
• SGDID: S000004572
• Length: 1127
• Species: Saccharomyces cerevisiae
• Alignment Length: 559
• Identity: 107/559 - (19%)
• Similarity: 198/559 - (35%)
• Gaps: 146/559 - (26%)

  Fly    36 RRLQESAHKISQK--FSGKELATERDESVQE-------------LCESLEELMSYGLRQSAGTSS 85
            :||..|.:.|..|  |.|.|:.|...:..:|             |.|....|.|..|:.....|.
Yeast   372 KRLLLSLNLIESKLSFPGSEIDTASKKLAREANYPDLNMDNGIVLKEMASFLTSITLKDIVDDSE 436

  Fly    86 FSA--ASFIQNMQEMVSGNAGGGSNNNDATFWEFCQT---------------HLTPHERQRYMDL 133
            |..  .||:.::.|           ...:||.|:.||               .::.:.....|.|
Yeast   437 FLPFFESFLGSVPE-----------TQGSTFLEYSQTIESFKNPLEDATSEDIISGYSGISTMQL 490

  Fly   134 KQIWTNVGRGRAFIRATLNEKRLHSHVLTW-----LSDEEQLHRFYTPWSLLLNDEAA------- 186
            ::|.:............|.::.|..:::.:     ::::|..........|||..||.
Yeast   491 QEISSKFFHNNNLQNMKLLDEGLVKNIILFRNSFQINNDEDTFILARKSVLLLQTEAIKYLDDRF 555

  Fly   187 ----KKLPEIVDSLSDVLFALNVDTTEL-----------NAPRRSTPSVAVKEEPIIFTTSPVPV 236
                ||.|..:..||    ..::.:|::           |.|.::.   .:|:.......:||.:
Yeast   556 LPLFKKTPSFLKMLS----TSHIISTDIYAHFLSRIGGVNNPEQNK---IIKDNVKTDFMNPVRI 613

  Fly   237 VGRQKRPGI--AVERPIECVSSTEDLLGALKPIESVEVQQILSKESIEQELAQPQEEVNLGPFDP 299
            ..   .|||  |::..:....|        ||.:|    :|.|.....|......:.:
Yeast   614 FA---NPGITDALDNIVNGSGS--------KPHKS----RISSNPRYSQLFGSENDNI------- 656

  Fly   300 IEPELEFLKTPLPDIGAHVGESELYEDRSDTSSQWSK-SSSSANCLANSQQ----------QAAL 353
                  |......|...:..|..:.||:.|......| |.||.|...|..|          .|:|
Yeast   657 ------FKDKLFDDENDNTSEISVVEDQLDHPRNMEKVSVSSGNSGLNPSQFYGSNNFRDNIASL 715

  Fly   354 EEHVNQLNERCALLETRVAELSLQNRLLIRRLTKQFEET---GIDPSSSLCSNFLI--------- 406
            ...::|:.:...||...:.:..|.|..:..::.|:.:.|   .::....|...:::
Yeast   716 TISIDQIEKELELLRHLILKADLTNNQMQLKILKKSQRTLLKELEMKELLKQQYMVQENGNSLFR 780

  Fly   407 -TIPHVKLAKTQRSG------SHYTYEVHITMRQRLEHWTFFRRYSEFYKLHKSLLKT-HPVVSA 463
             |..:::...::.|.      ::|...:|.....::..|...|||:||::|:..|.|. ..::..
Yeast   781 KTKIYIRSYFSENSSNGLKEITYYIINIHHFNNGQVSSWDMARRYNEFFELNTYLKKNFRDLMRQ 845

  Fly   464 VE--FPPK-----KHFGNMNLVFVEERRQQLQIYLLNLV 495
            ::  ||.|     |:.....|:: |||:|:|:.||..|:
Yeast   846 LQDLFPSKVKMSLKYHVTKTLLY-EERKQKLEKYLRELL 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	37..206	CDD:459241	41/216 (19%)
		PX_RUN	404..520	CDD:132810	26/116 (22%)
MDM1	NP_013603.1	PXA	85..276	CDD:214611
		RGS	462..567	CDD:470619	15/104 (14%)
		PX_MDM1p	763..900	CDD:132786	27/122 (22%)
		Nexin_C	993..1106	CDD:462541