Protein Alignment CG5439 and Snx29

DIOPT Version :10

• Sequence 1: NP_609607.1
• Gene: CG5439 / 34710
• FlyBaseID: FBgn0032476
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001390164.1
• Gene: Snx29 / 74478
• MGIID: 1921728
• Length: 819
• Species: Mus musculus
• Alignment Length: 795
• Identity: 169/795 - (21%)
• Similarity: 276/795 - (34%)
• Gaps: 314/795 - (39%)

  Fly    22 LAGSTFGQRREDIFRRLQESAHKISQKFSG-KELATERDESVQELCESLEELMSYGLRQSAGTSS 85
            ::||....||:.:..||.::..:...:|.| ||:|::.|..|..||...|.::.:|:::|.|.:.
Mouse     1 MSGSQNDDRRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGMKRSRGLAL 65

  Fly    86 FSAASFIQNMQEMVSGNAGGGS-NNNDATFWEFCQTHLTPHERQRYMDLKQIWTNVGRGRAFIRA 149
            .:||         :...||..| ...:..||.:.:..|..||.||:..|..|.::.|||||::|.
Mouse    66 TAAA---------IKQAAGFTSKTETEPVFWVYVKEVLNKHELQRFYSLHHITSDAGRGRAWLRC 121

  Fly   150 TLNEKRLHSHVLTWLSDEEQLHRFYTPWSLLLNDEAAKKLPEIVDSLSDVLFALNVDTTELNAPR 214
            .|||..|..::...|:|..:|..||..||.::::|.:..||.:...|:.:|||:|:|..:||...
Mouse   122 ALNEHSLERYLHMLLADRARLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQS 186

  Fly   215 RSTPSVA--VKEEPIIFT--------------------------------TSPVPVVGR------ 239
            :..|:|:  :||.....|                                |.|:||:.:
Mouse   187 KFAPTVSDLLKESTQNVTSLLKESTQGMSSLLREITASSAVSILIKPEQETDPLPVISKNVHVDT 251

  Fly   240 -------------------------------QKRPGIAVERPIECVSSTEDLLGALK-------- 265
                                           :|.||.|.........|:.:::.|.:
Mouse   252 RCKRERRRRKKVTNIVSFDDDEEEQGTGDTLKKMPGTAESSEENSDRSSVNIMAAFEGTFGPNSN 316

  Fly   266 --------PIESVEVQ-----QILSKESIEQELAQPQEEVNLGPFD------------------- 298
                    .|:|..:.     |.|..:||:.::.:.:|:....|..
Mouse   317 GSQSSSSWKIDSASLNGELGYQKLDVKSIDDDVDENEEDAYRSPLGRGHTGHAESPDRTLDGNAC 381

  Fly   299 --------------------------------------PI---------------EPELEFLK-- 308
                                                  |:               ||.|.:.:
Mouse   382 LAQVHGWAPLQVLHGDADADTDVLFPVSGVGSYGAADAPVGSLENGTGTENHIIPEPGLRYSREA 446

  Fly   309 ------TPLPDI--GAHVGES----ELYE------DRSDTSSQWSKSSSSANCL--------ANS 347
                  :||..:  .|.|.||    ||.:      :|.|...:  ::.|..|.|        |..
Mouse   447 SSPGQGSPLSSLLPSASVPESMTVHELRQAIVAMMNRKDELEE--ENGSLRNLLDGEMEHSAALR 509

  Fly   348 QQQAALEEHVNQLNERCALLETRVAELSLQNRLLIRRLTK------------------------- 387
            |:..||...|.:..||.|   |:|..|:.:|.:|..:|.|
Mouse   510 QEVDALRRKVTEQQERHA---TKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEAVPSLWNVD 571

  Fly   388 ------------------------------------QFEE------------------------- 391
                                                :|.|
Mouse   572 AEVTVPEQKPGEVAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRG 636

  Fly   392 --------TGIDPSSS---LCSNFLIT--IPHVKLAKTQRSGSHYTYEVHITMRQRLEHWTFFRR 443
                    |..|.|.|   :.:..||.  ||.|.| :.:.:.:.:.|:|:|.::.  :.|..:||
Mouse   637 PVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFL-RGKAANAFHVYQVYIRIKD--DEWNVYRR 698

  Fly   444 YSEFYKLHKSLLKTHPVVSAVEFPPKKHFGNMNLVFVEERRQQLQIYLLN----LVETLPQVEAC 504
            |:||..||..|....|.|.|..|||||..||.:..||||||:|||.||.:    :::.:|:..|.
Mouse   699 YTEFRALHHQLQSAFPQVRAYSFPPKKAIGNKDAKFVEERRKQLQSYLRSVMNKVIQMVPEFAAN 763

  Fly   505 KSKAELQKVFPFFRD 519
            ..|..|.::.|||.|
Mouse   764 PKKETLVQLVPFFVD 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	37..206	CDD:459241	54/170 (32%)
		PX_RUN	404..520	CDD:132810	47/122 (39%)
Snx29	NP_001390164.1	RUN_SNX29	16..178	CDD:439051	54/170 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	267..299		4/31 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	343..375		4/31 (13%)
		Ax_dynein_light	<466..546	CDD:463000	23/84 (27%)
		SMC_prok_B	<472..>652	CDD:274008	27/184 (15%)
		PX_RUN	662..779	CDD:132810	46/120 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	782..819