DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG5439 and SNX16

DIOPT Version :9

Sequence 1:NP_609607.1 Gene:CG5439 / 34710 FlyBaseID:FBgn0032476 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_071416.2 Gene:SNX16 / 64089 HGNCID:14980 Length:344 Species:Homo sapiens


Alignment Length:235 Identity:59/235 - (25%)
Similarity:88/235 - (37%) Gaps:88/235 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   306 FLKTPLPDIGAHVGESELYEDRSDTSSQWSKSSSSANCLANSQQQAALEEHVNQLNERCALLETR 370
            ::..|:| ||.  ..|....:|:..||.:...|:|:|   :|:.|.   |..|..|         
Human     5 YVPVPMP-IGN--SASSFTTNRNQRSSSFGSVSTSSN---SSKGQL---EDSNMGN--------- 51

  Fly   371 VAELSLQNRLLIRRLTKQFEETGI----DPSSSLCSNFLITIPHVKLAKTQRSGSHYT------- 424
                              |::|.:    |.:||:||:.||   ..|...|..|..:.|       
Human    52 ------------------FKQTSVPDQMDNTSSVCSSPLI---RTKFTGTASSIEYSTRPRDTEE 95

  Fly   425 -------------------YEVHITMRQRL--------------EHWTFFRRYSEFYKLHKSLLK 456
                               |||   |.:|.              |.|..||||::|.:|:..|.:
Human    96 QNPETVNWEDRPSTPTILGYEV---MEERAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKE 157

  Fly   457 THPVVSAVEFPPKKHF-GNMNLVFVEERRQQLQIYLLNLV 495
            ..|.. .:..|||:.| .|.|..|:|:|:..||.:|.|||
Human   158 MFPGF-RLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLV 196

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5439NP_609607.1 RUN 64..206 CDD:280855
PX_RUN 404..520 CDD:132810 36/133 (27%)
SNX16NP_071416.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..66 19/96 (20%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 81..107 2/25 (8%)
PX_SNX16 105..214 CDD:132809 30/96 (31%)
SMC_N <231..>336 CDD:330553
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2101
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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