DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5439 and rufy2

DIOPT Version :9

Sequence 1:	NP_609607.1	Gene:	CG5439 / 34710	FlyBaseID:	FBgn0032476	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001231848.1	Gene:	rufy2 / 569096	ZFINID:	ZDB-GENE-070424-66	Length:	698	Species:	Danio rerio

Alignment Length:	404	Identity:	69/404 - (17%)
Similarity:	151/404 - (37%)	Gaps:	108/404 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 DLKQIWTNVGRGRAFIRATLNEKRLHSHVLTWLSDEEQLHRFYTPWSLLLNDEAAKKLPEIVDSL 196
            ||..:.|.:||.||::|..|.:|:|..::...::.::.|..||...:::|.:|.|
Zfish   184 DLPGLKTPLGRARAWLRLALMQKKLADYLRLLITRKDILSEFYESSAVMLEEEGA---------- 238

  Fly   197 SDVLFALNVDTTELNAPRRSTPSVAVKEEPI----------IFTTSPVPVVGRQKRPGIAVERPI 251
              |:..|.|....::|      ::.||.|.:          ::..:.:.....::|.|     .|
Zfish   239 --VIVGLLVGLNVIDA------NLCVKGEDLDTQVGVIDFSMYLKNDIDDYRSEERNG-----QI 290

  Fly   252 ECVSSTEDLLGALKPIESVEVQQILSK-ESIEQELAQPQEEVNLGPFDPIEPELEFLKTPLPDIG 315
            ..:...::.:..|....:..||.:..: ||:|:..::..||:.:...:.|:.
Zfish   291 AAILDQKNYVEELNRQLNSTVQGLQGRVESLEKNNSKLIEELAIAKNNIIKL------------- 342

  Fly   316 AHVGESELYEDRSDTS-------SQWSKSSSSANCLANSQQQA--ALEEHVN----QLNERCALL 367
                :.|.::.|::.|       .:.:.:....:|..::.:|:  .|:|..|    ||.|.|.|.
Zfish   343 ----QEENHQLRTENSVILMKAQQRLAVTEGDLSCELDTYKQSRQGLDEMYNEARRQLKEECQLR 403

  Fly   368 ETRVAELSLQNRLLIRRLTKQFEETGIDPSSSLCSNFLITIPHVKLAKTQRSGSHYTYEVHITMR 432
            :      .::|.|:::...||..|..:                    |......|...:..|.:|
Zfish   404 Q------DVENELVVQVSMKQEMEMAM--------------------KLLEKDIHEKQDTLIGLR 442

  Fly   433 QRLEHWTFF--RRYSEFYKLHKSLLKTHPVVSAVEFPPKKHFGNMNLVFVEERRQQLQIYLLNLV 495
            .:|:.....  ..|.:......|:.:.:.:::.                :||:..|:...:..|.
Zfish   443 HQLDEVKAINVEMYQKMQSSDDSMRQKNDMIAR----------------LEEKTNQITATMKQLE 491

  Fly   496 ETLPQVEACKSKAE 509
            :.|...|..::.||
Zfish   492 QRLQDAERERASAE 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	64..206	CDD:280855	19/73 (26%)
CG5439	NP_609607.1	PX_RUN	404..520	CDD:132810	15/108 (14%)
rufy2	NP_001231848.1	RUN	135..258	CDD:280855	22/91 (24%)
		Taxilin	300..625	CDD:286771	42/265 (16%)
		FYVE_RUFY2	626..696	CDD:277298
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4381
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900