Protein Alignment CG5439 and KIF16B

DIOPT Version :9

• Sequence 1: NP_609607.1
• Gene: CG5439 / 34710
• FlyBaseID: FBgn0032476
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_005260807.1
• Gene: KIF16B / 55614
• HGNCID: 15869
• Length: 1883
• Species: Homo sapiens
• Alignment Length: 604
• Identity: 117/604 - (19%)
• Similarity: 213/604 - (35%)
• Gaps: 187/604 - (30%)

  Fly     9 MPTEAGFRSMRSQLAGSTFGQRREDIFRRLQESAHKISQKFSGKELATERDESVQELCESLEELM 73
            |..|...:...:::......::.|.:.||   |.| |..|.  |:|..|:::..:|.....:|:.
Human   644 MQQEVETQRKETEIVQLQIRKQEESLKRR---SFH-IENKL--KDLLAEKEKFEEERLREQQEIE 702

  Fly    74 SYGLRQSAGTSSFSAASFIQNMQEMVSGNAGGGSNNNDATFWEFCQTHLTPHERQRYMDLKQIWT 138
            ....||...| .......:|.::|:         |||:..           .:.|.:.:|.|:..
Human   703 LQKKRQEEET-FLRVQEELQRLKEL---------NNNEKA-----------EKFQIFQELDQLQK 746

  Fly   139 NVGRGRAFIRATLNEKRLH----------SHVLTWLSDEEQ----LHRFYTPWSLLLNDEAAKKL 189
            .  :...:.:..|.:|||.          :|:...|.::::    |.|....|.    :|..:.|
Human   747 E--KDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWV----EEEKRDL 805

  Fly   190 PEIVDSLSDVLFAL---NVDTTELNA--------PRRSTPSVAVKEEPIIFTTSPVPVVGRQKRP 243
            ..|.:||..|..|.   :.|..||..        .||....:...|:.::           |::.
Human   806 EGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLV-----------QQKD 859

  Fly   244 GIAVERPIECVSSTEDLLGALKPIESVEVQQILSK--ESIEQELAQPQEEVNLGPFDPIEP---- 302
            .:..|     |...:::|..|| .|..:..::|.|  ||:......||:      |:.|:|
Human   860 ILKKE-----VQEEQEILECLK-CEHDKESRLLEKHDESVTDVTEVPQD------FEKIKPVEYR 912

  Fly   303 ------ELEF-LKTPLP-------------DIGAHVGESELYE---DRSDTSSQWSKSSSSANCL 344
                  :|:: |:..||             |.|....::.||:   :..:...|.::..::||.|
Human   913 LQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQL 977

  Fly   345 ----------AN--------------------SQQQAALEEHVNQLNERCALLE---TRVAELSL 376
                      ||                    .||:.|||..:.:|..|.:.|:   |...|:..
Human   978 QKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEE 1042

  Fly   377 QNRLLIRRLTKQFEETGIDPSSSLCSNFLITIPHVKLAKTQRSGSHYTYEVHITMRQRL------ 435
            |.:.|....:...|::|:..|        :......|.|.|   ....||:. .::|::
Human  1043 QRQKLASLNSGSREQSGLQAS--------LEAEQEALEKDQ---ERLEYEIQ-QLKQKIYEVDGV 1095

  Fly   436 ---EHWTFFRRYSEFYKLHKSLLKTH--PVVSAVEFPPKKHFGNMNLVFVEERRQQLQIYLLNLV 495
               .|.|...:.:. ..|..|..|:|  |::.|          .:|....||.:::||
Human  1096 QKDHHGTLEGKVAS-SSLPVSAEKSHLVPLMDA----------RINAYIEEEVQRRLQ------- 1142

  Fly   496 ETLPQV--EACKSKAELQK 512
             .|.:|  |.|.:.|:..|
Human  1143 -DLHRVISEGCSTSADTMK 1160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	64..206	CDD:280855	29/158 (18%)
		PX_RUN	404..520	CDD:132810	25/122 (20%)
KIF16B	XP_005260807.1	KISc_KIF1A_KIF1B	2..365	CDD:276816
		KISc	3..365	CDD:214526
		Kinesin_assoc	364..476	CDD:292801
		FHA	478..543	CDD:278899
		TPH	610..934	CDD:290579	67/345 (19%)
		GBP_C	<618..818	CDD:303769	40/206 (19%)
		coiled coil	808..818	CDD:293879	4/9 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900