DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5439 and PXK

DIOPT Version :9

Sequence 1:	NP_609607.1	Gene:	CG5439 / 34710	FlyBaseID:	FBgn0032476	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001336421.1	Gene:	PXK / 54899	HGNCID:	23326	Length:	581	Species:	Homo sapiens

Alignment Length:	129	Identity:	39/129 - (30%)
Similarity:	61/129 - (47%)	Gaps:	21/129 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   407 TIP-HVKLAKTQRSGSHYTYEVHITMRQRLEH-WTFFRRYSEFYKLHKSLLKTHPVVSAVEFPPK 469
            |:| ...:..:|...||..|.:.:.....:|: |...||||:|..|:.||   .....::..|||
Human    17 TVPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSL---QIAGLSLPLPPK 78

  Fly   470 KHFGNMNLVFVEERRQQLQIYLLNLVETLPQVEACK---------------SKAELQKVFPFFR 518
            |..|||:..|:.||::.||.| ||::.|...:..|:               ::..||:|..|||
Human    79 KLIGNMDREFIAERQKGLQNY-LNVITTNHILSNCELVKKFLDPNNYSANYTEIALQQVSMFFR 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	64..206	CDD:280855
CG5439	NP_609607.1	PX_RUN	404..520	CDD:132810	39/129 (30%)
PXK	NP_001336421.1	PX_MONaKA	13..132	CDD:132781	33/118 (28%)
		SPS1	186..492	CDD:223589
		PKc	198..345	CDD:270622
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900