DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5439 and Rufy3

DIOPT Version :9

Sequence 1:NP_609607.1 Gene:CG5439 / 34710 FlyBaseID:FBgn0032476 Length:520 Species:Drosophila melanogaster
Sequence 2:XP_006535172.1 Gene:Rufy3 / 52822 MGIID:106484 Length:687 Species:Mus musculus


Alignment Length:521 Identity:99/521 - (19%)
Similarity:167/521 - (32%) Gaps:199/521 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 VQELCESLEELMSYGLRQSAGTSSFSAASFIQNMQEMVSGNAGGGSNNNDATFW---EFCQTHLT 123
            :|:....:|..:.:||:        :..:|:             |.|.   :||   |..: .|.
Mouse   169 LQQFFVVMEHCLKHGLK--------AKKTFL-------------GQNK---SFWGPLELVE-KLV 208

  Fly   124 PHERQ---RYMDLKQIWTNVGRGRAFIRATLNEKRLHSHVLTWLSDEEQLHRFYTPWSLLLNDEA 185
            |...:   ...||..:.|.||||||::|..|.:|:|..::...::.:|.|..||...:|::.:|.
Mouse   209 PEAAEITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEVNALMMEEEG 273

  Fly   186 A---------------------------------------------------------------- 186
            |                                                                
Mouse   274 AIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKDGNSSKGSEGDGQITAILDQKNYVEEL 338

  Fly   187 -KKLPEIVDSLSDVLFALNVDTTELNAPRRSTPSVAVKEEPIIFTTSPVPVVGRQ-------KRP 243
             :.|...|::|...:..|....|:|      |..:||....||.....:..|..:       .|.
Mouse   339 NRHLNATVNNLQTKVDLLEKSNTKL------TEELAVANNRIITLQEEMERVKEESSYLLESNRK 397

  Fly   244 GIAVERPIE----------CVSSTEDLLGALKPIE---SVEVQQILSKESIEQELAQPQEEV--- 292
            |...:|..|          ....|:..|...|.:|   |:..:..|:.:.:|:::.:.|:.:   
Mouse   398 GPKQDRTAEGQALSEARKHLKEETQLRLDVEKELELQISMRQEMELAMKMLEKDVCEKQDALVSL 462

  Fly   293 --NLGPFDPIEPELEFLKTPLPDIGAHVGESELYEDRSDTSSQWSKSSSSANCLANSQQQAALEE 355
              .|.....::.||.| |....|:|.                   |..|..|        :.|||
Mouse   463 RQQLDDLRALKHELAF-KLQSSDLGV-------------------KQKSELN--------SRLEE 499

  Fly   356 HVNQLNERCALLETRV--AELSLQNRLLIRRLTKQFEETGIDPSSSL----------CSNFLITI 408
            ..||:......||.|:  ||...|:..|..||.||  :.| |..:||          .:...:.:
Mouse   500 KTNQMAATIKQLEQRLRQAERGRQSAELDNRLFKQ--DFG-DKINSLQLEVEALTRQRTQLELEL 561

  Fly   409 PHVKLAKTQR---------------SGSHYTYEVHITMRQRLEHWTFFRRYSEFYKLHKSLLKTH 458
            ...|..|:|.               .|.|...|.::.:::.||            :.|:  |.||
Mouse   562 KQEKERKSQNRGTPGKGAQKPELRMDGKHRIQEENVKLKKPLE------------ESHR--LLTH 612

  Fly   459 P 459
            |
Mouse   613 P 613

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5439NP_609607.1 RUN 64..206 CDD:280855 35/212 (17%)
PX_RUN 404..520 CDD:132810 13/71 (18%)
Rufy3XP_006535172.1 RUN 171..292 CDD:367169 31/145 (21%)
Smc <340..>570 CDD:224117 56/266 (21%)
FYVE_RUFY3 629..675 CDD:277283
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4381
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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