DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5439 and CG31064

DIOPT Version :9

Sequence 1:	NP_609607.1	Gene:	CG5439 / 34710	FlyBaseID:	FBgn0032476	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001287560.1	Gene:	CG31064 / 43277	FlyBaseID:	FBgn0051064	Length:	877	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	97/503 - (19%)
Similarity:	182/503 - (36%)	Gaps:	127/503 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 LEELMSYGLRQSAGTSSFSAASFIQNMQEMVSGNAGGGSNNNDATFWEFCQT--HLTPHERQ--- 128
            :|.::.:|||...|        .:...:|:                |:..|:  |..|..:.
  Fly   321 IEHVLGHGLRPKKG--------LLGPRKEL----------------WDLLQSVEHYCPEAQDITA 361

  Fly   129 RYMDLKQIWTNVGRGRAFIRATLNEKRLHSHVLTWLSD-EEQLHRFYTPWSLLLNDEAAKKL--- 189
            ...||..:.|::||.||::|..|.:|:|..::...:.. |:.|..:|.|.:|:::||....:
  Fly   362 SVRDLPTVRTHIGRARAWLRIALMQKKLSDYLQALIEHREDSLFDYYEPHALMMSDEIVVIMGIL 426

  Fly   190 -------------PEIVDSLSDVL-FALNVDTTELN---APRRSTP-----------SVAVKEEP 226
                         .|.:||...|: |:|.:.::..|   ||..|.|           .:||.::
  Fly   427 VGLNVIDCNLCVKEEDLDSQQGVIDFSLYLRSSSRNADAAPEDSAPPALLDATGQGNMIAVLDQ- 490

  Fly   227 IIFTTSPVPVVGRQKRPGIA-VERPIECVSST-----EDLLGALKPIESVEVQQILSKESIEQEL 285
                .:.:..:.|.....:. ::..:|.:::|     |||..|...:.:::.:....::|..
  Fly   491 ----KNYIEELNRHLNATVGNLQAKVESLTTTNALMKEDLAIARNSLLALQAENQAMRQSTS--- 548

  Fly   286 AQPQEEVNLGPFDPIEPELEFLKTPLPDIGAHVGESELYEDRSDTSSQWSKSSSSANCLANSQQ- 349
            |........|.....:.|              ....||.|:|...|....:.....:..|.|..
  Fly   549 AGDNNSTGSGGSSDKDKE--------------KASEELVEERRKNSELEKELKLQVSLKAESDMA 599

  Fly   350 QAALEEHVNQLNERCALLETRVAELSLQNRLLIRRLTKQFEETGIDPSSSLC-SNFLITIPHVKL 413
            ...||:.:::..:....|..::.::...|..:.|:|.        |..:||. ...|:|    ||
  Fly   600 MKLLEKDIHEKQDTIVSLRRQLDDIKQINLEMYRKLQ--------DCKASLTHKTELMT----KL 652

  Fly   414 AKTQRSGSHYTYEVHITMRQRLEHWTFFR-RYSEFYKLHKSLLKTHPVVSAVEFPPKKHFGNMNL 477
             :.|:.      ::..|:.|..:.|:..: ...|..|.....|.|.  |:|.|....:......:
  Fly   653 -EVQKE------DMASTIDQLEKKWSHDKSNLGEILKTTSQTLTTQ--VTASEERAARAEAESRI 708

  Fly   478 VFVEERRQQLQIYLLNLVETLPQVEAC------------KSKAELQKV 513
              ..|.|..||...|.|.|.:..::.|            |.||:|.||
  Fly   709 --EREWRISLQEKELKLKEKIANLQGCLKELSEEKERNGKLKADLDKV 754

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	64..206	CDD:280855	34/159 (21%)
CG5439	NP_609607.1	PX_RUN	404..520	CDD:132810	29/123 (24%)
CG31064	NP_001287560.1	RUN	316..439	CDD:280855	28/141 (20%)
		CASP_C	495..>634	CDD:285395	22/155 (14%)
		FYVE_RUFY1_like	813..874	CDD:277261
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4381
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900