Protein Alignment CG5439 and Rufy1

DIOPT Version :9

• Sequence 1: NP_609607.1
• Gene: CG5439 / 34710
• FlyBaseID: FBgn0032476
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001094197.1
• Gene: Rufy1 / 360521
• RGDID: 1305099
• Length: 711
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 124/610 - (20%)
• Similarity: 217/610 - (35%)
• Gaps: 188/610 - (30%)

  Fly     4 NASSSMPTEAGFRSMRSQLAGSTFGQRREDIFRRLQESAH-----KISQKF---SGKELATERDE 60
            :..|::...||...     .|...|:|.....:.::|.|:     |:|.|.   |...|....|.
  Rat    84 SCGSALRAAAGLGD-----GGGGGGERAASKGQMMEERANLMHMMKLSIKVLLQSALSLGRSLDA 143

  Fly    61 S---VQELCESLEELMSYGLRQ-----SAGTSSFSAASFIQNMQEMVSGNAGGGSNNNDATFWEF 117
            .   :|:....:|..:.:||:.     ....|.|.....::.:....|..|....|
  Rat   144 DHAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKLCPEASDIATSVRN--------- 199

  Fly   118 CQTHLTPHERQRYMDLKQIWTNVGRGRAFIRATLNEKRLHSHVLTWLSDEEQLHRFYTPWSLLLN 182
                           |.::.|.||||||::...|.:|:|..::...:.::..|..||.|.:|::.
  Rat   200 ---------------LPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMME 249

  Fly   183 DEAAKKLPEIVDSLSDVLFALNVDTTELNAPRRSTPSVAVKEEPIIFTTSPVPVV---------- 237
            :|..            |:..|.|....|:|      ::.:|.|.:   .|.|.|:
  Rat   250 EEGM------------VIVGLLVGLNVLDA------NLCLKGEDL---DSQVGVIDFSLYLKDVQ 293

  Fly   238 ----GR----------QKRPGIAVERPIEC-VSSTEDLLGALKPIESVEVQQILSKE-----SIE 282
                ||          ||.....:.|.:.| |...:..:..|:...| ::|:.||..     |::
  Rat   294 DLDSGREHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNS-KLQEELSAATDRICSLQ 357

  Fly   283 QELAQPQEEVNLGPFDPIEPELEFLKTPLPDIGAHVGESELYEDRSDTSSQWSKSSSSANCLANS 347
            :|..|.:|                             ::||..:||:.|.:.:|..:........
  Rat   358 EEQQQLRE-----------------------------QNELIRERSEKSVEITKQDTKVELETYK 393

  Fly   348 QQQAALEEHVN----QLNE----RCAL---LETRV---AELSLQNRLL----------IRRLTKQ 388
            |.:..|:|..:    ||.|    |..|   ||.::   .|:.:..:||          :..|.:|
  Rat   394 QTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQ 458

  Fly   389 FEETGIDPSSSLCSNFLITIPHVKLAKTQRSGSHYTYEVHIT--------MRQRLEHWTFFRRYS 445
            .||.     .::.......:...:.:..|:..:..::|...|        |.:||:.....|:.:
  Rat   459 LEEV-----KAINLQMFHKVQSAESSLQQKDEAIASFEGKTTQVMSSMKQMEERLQQAERARQGA 518

  Fly   446 E--FYKLHKSLLKTHPVVSAVEFPPKKHFGNMN-----LVFVEERRQQLQIYLLN------LVET 497
            |  .|||.:.|...   |||::....:.....:     |...:|:||.||..|.:      |::|
  Rat   519 EERSYKLQQELSGR---VSALQLQLSQLRDQCSGLEKELKSEKEQRQTLQRELQHEKDTSCLLQT 580

  Fly   498 -LPQVEACK--------SKAELQKV 513
             |.|||..|        .||||:||
  Rat   581 ELQQVEGLKKELRELQDEKAELRKV 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	64..206	CDD:280855	27/146 (18%)
		PX_RUN	404..520	CDD:132810	35/140 (25%)
Rufy1	NP_001094197.1	RUN	150..273	CDD:280855	30/164 (18%)
		DUF3422	<443..588	CDD:295160	32/152 (21%)
		FYVE_RUFY1	637..707	CDD:277297

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4381
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900