DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5439 and Snx14

DIOPT Version :9

Sequence 1:	NP_609607.1	Gene:	CG5439 / 34710	FlyBaseID:	FBgn0032476	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001346887.2	Gene:	Snx14 / 244962	MGIID:	2155664	Length:	946	Species:	Mus musculus

Alignment Length:	396	Identity:	81/396 - (20%)
Similarity:	128/396 - (32%)	Gaps:	128/396 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 LSDEEQLHRFYTPWSLLLNDEAAKKL---PEIVDSLSDVLFALNVDTTELNAPR----------- 214
            ||..|:|.:.|..:.|   ||:..|:   |.||:.:..:.....:|..:|...|
Mouse   387 LSLHEELQKIYKTYCL---DESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLS 448

  Fly   215 ----RSTPSVAVKEEPIIFTTSPVPVVGRQKRPGIAVERPIECVS------STEDLLGALKPIES 269
                ..||.....:|..           ||...|  .|.|.....      |.:|.....|..||
Mouse   449 LLENVFTPMFCHSDEYF-----------RQLLRG--AESPTRNSKFNRGSLSLDDFRSTQKRGES 500

  Fly   270 VEVQQILSKESIEQELAQPQEEVNLGPFDPIEPELEFLKTPLPDIGAHVGESELYEDRSDTSSQW 334
            ..:.:|.||..              |.|.....|    ...||:.|...||.:.
Mouse   501 FGISRIGSKIK--------------GVFKSTTME----GAVLPNYGVAEGEDDF----------- 536

  Fly   335 SKSSSSANCLANSQQQAALEEHVNQLNERCALLETRVAELSLQN---RLLIRRLTKQFEETGIDP 396
                              :||.:..:.:     ::.|..:|..|   .|...:::..:.:...||
Mouse   537 ------------------IEEGIVVMED-----DSPVEAVSTPNTPRNLAAWKISIPYVDFFEDP 578

  Fly   397 SSSLCSN------FLITIPHVKLAKTQRSGSHYTYEVHITMRQRLEHWTFFRRYSEFYKLHKSLL 455
            ||.....      |.|.:..    ..:|:..|           ..|||:.:|||.|||.|...|.
Mouse   579 SSERKEKKERIPVFCIDVER----NDRRAVGH-----------EPEHWSVYRRYLEFYVLESKLT 628

  Fly   456 KTHPVVSAVEFPPKKHFGNMNLVFVEERRQQLQIYLLNLVETLPQVEACKSKAE----------- 509
            :.|......:.|.|:..|..|..|::.:|::.|.||..||:. |::...:..|:
Mouse   629 EFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLVQH-PELSNSQLLADFLSPNGGETQF 692

  Fly   510 LQKVFP 515
            |.|:.|
Mouse   693 LDKILP 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	64..206	CDD:280855	12/44 (27%)
CG5439	NP_609607.1	PX_RUN	404..520	CDD:132810	32/123 (26%)
Snx14	NP_001346887.2	PXA	130..299	CDD:308031
		RGS_SNX14	340..466	CDD:188677	18/92 (20%)
		PX_SNX14	564..686	CDD:132787	33/137 (24%)
		Nexin_C	807..911	CDD:337134
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900