Protein Alignment CG5439 and Rufy1

DIOPT Version :9

• Sequence 1: NP_609607.1
• Gene: CG5439 / 34710
• FlyBaseID: FBgn0032476
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_766145.1
• Gene: Rufy1 / 216724
• MGIID: 2429762
• Length: 712
• Species: Mus musculus
• Alignment Length: 546
• Identity: 97/546 - (17%)
• Similarity: 189/546 - (34%)
• Gaps: 151/546 - (27%)

  Fly     4 NASSSMPTEAGFRSMRSQLAGSTFGQRREDIFRRLQESAH-----KISQKF---SGKELATERDE 60
            :..|::...||...      |...|:|.....:.::|.|:     |:|.|.   |...|....|.
Mouse    86 SCGSALRAAAGLGD------GGGGGERAASKGQMMEERANLMHMMKLSIKVLLQSALSLGRSLDA 144

  Fly    61 S---VQELCESLEELMSYGLRQ-----SAGTSSFSAASFIQNMQEMVSGNAGGGSNNNDATFWEF 117
            .   :|:....:|..:.:||:.     ....|.|.....::.:....|..|....|
Mouse   145 DYAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLELVEKLCPEASDIATSVRN--------- 200

  Fly   118 CQTHLTPHERQRYMDLKQIWTNVGRGRAFIRATLNEKRLHSHVLTWLSDEEQLHRFYTPWSLLLN 182
                           |.::.|.||||||::...|.:|:|..::...:.:::.|..||.|.:|::.
Mouse   201 ---------------LPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKQLLSEFYEPEALMME 250

  Fly   183 DEAAKKLPEIVDSLSDVLFALNVDTTELNAPRRSTPSVAVKEEPIIFTTSPVPVVGRQKRPGIAV 247
            :|..            |:..|.|....|:|      ::.:|.|.:   .|.|.|:....
Mouse   251 EEGM------------VIVGLLVGLNVLDA------NLCLKGEDL---DSQVGVIDFSL------ 288

  Fly   248 ERPIECVSSTEDLLGALKPIESVEVQQILSKESIEQEL----------------------AQPQE 290
                 |:...:||....   |...:..:|.:::..:||                      ::.||
Mouse   289 -----CLKDAQDLDSGR---EHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGLEKTNSKLQE 345

  Fly   291 EVNLGP--FDPIEPELEFLKTPLPDIGAHVGESELYEDRSDTSSQWSKSSSSANCLANSQQQAAL 353
            |::...  ...::.|.:.|:.          ::|:..:||:.|.:.:|..:........|.:..|
Mouse   346 ELSAATDRICSLQKEQQQLRE----------QNEVIRERSEKSVEITKQDTKVELETYKQTRQGL 400

  Fly   354 EEHVNQLNERCALLETRVAELSLQNRLLIRRLTKQFEETGIDPSSSLCSNFLITIPHVKLAKTQR 418
            :|..:.:.::  |.|.:...|.|:..|.:        :.|:.....:....|            .
Mouse   401 DEMYSDVWKQ--LKEEKKVRLELEKELEL--------QIGMKTEMEIAMKLL------------E 443

  Fly   419 SGSHYTYEVHITMRQRLEHWTFFRRYSEFYKLHKSLLKTHPVVSAVEFPPKKHFGNMNLVFVEER 483
            ..:|...:..:.:||:||         |...::..:.  |.|.||.....:|   |..:...|.:
Mouse   444 KDTHEKQDTLVALRQQLE---------EVKAINLQMF--HKVQSAESSLQQK---NEAIASFEGK 494

  Fly   484 RQQLQIYLLNLVETLPQVEACKSKAE 509
            ..|:...:..:.|.|.|.|..:..||
Mouse   495 TTQVMSSMKQMEERLQQAERARQAAE 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	64..206	CDD:280855	27/146 (18%)
		PX_RUN	404..520	CDD:132810	21/106 (20%)
Rufy1	NP_766145.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45
		RUN	151..274	CDD:280855	30/164 (18%)
		DUF3422	<444..589	CDD:295160	20/91 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	498..532		6/23 (26%)
		Interaction with RAB4. /evidence=ECO:0000269|PubMed:11172003	619..629
		FYVE_RUFY1	638..708	CDD:277297

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4381
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900