Protein Alignment CG5439 and RUNDC3B

DIOPT Version :9

• Sequence 1: NP_609607.1
• Gene: CG5439 / 34710
• FlyBaseID: FBgn0032476
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_612147.1
• Gene: RUNDC3B / 154661
• HGNCID: 30286
• Length: 473
• Species: Homo sapiens
• Alignment Length: 502
• Identity: 94/502 - (18%)
• Similarity: 190/502 - (37%)
• Gaps: 127/502 - (25%)

  Fly    48 KFSGKELATER-----DESVQE---LCESLEELMSYGLRQSAGTSSFSAASFIQNMQEMVSGNAG 104
            :||.|.|....     |:|..|   ....||:::|:.|::.:     .:..::.::|..:.|...
Human    41 RFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKEIS-----QSCRWLAHLQIPLQGQVT 100

  Fly   105 GGSNNNDATFWEFCQTHLTPHERQ---RYMDLKQIWTNVGRGRAFIRATLNEKRLHSHVLTWLSD 166
            .....:..:||::.:.......:.   ...:::.:.::..:|||:||..|.||.|..::.|.|.|
Human   101 WFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRD 165

  Fly   167 EEQLHRFYTPWSLLLNDEAAKKLPEIVDSLSDVLFALN-VDTTELNAPRRSTPSVAVKEE----- 225
            .:...|||...:::|.:||        :.|:.:|..|| :|.           |..:|.|
Human   166 FKTTRRFYEDGAIVLGEEA--------NMLAGMLLGLNAIDF-----------SFCLKGEGLDGS 211

  Fly   226 -PIIFTTSPVPVVGRQKRPGIAVERPIECVSSTEDLLGALKPIESVEVQQILSKESIEQELAQPQ 289
             |.:...:|.                ::.:.|::.:        |.:.:::.:..|...|.:.|:
Human   212 FPAVIDYTPY----------------LKYIQSSDSI--------SSDEEELRTLGSSGSESSTPE 252

  Fly   290 EEVNLGPFDPIEPELEFLKTPLPDIGAHVGESELYEDRSDTSSQWSKSSSSANCLANSQQQAALE 354
               |:||        .||                    .|.:|.::|      |....|:.....
Human   253 ---NVGP--------PFL--------------------MDENSWFNK------CKRVKQKYQLTL 280

  Fly   355 EHVNQLNERCALLETRVAELSLQNRLLIRR-----LTKQFEETGIDPSSSLCSNFLITIPHVKLA 414
            |....|.|...|.|.:::|...||::|::|     |..:.|:..::.......:.|..:.:..|.
Human   281 EQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLR 345

  Fly   415 KTQRSGSHYT--------YEVHITMRQRLEHWTFFRRYSE--FYKLHKSL--LKTHPVVSAVEFP 467
            ..|...:|.|        .:|:......|    .:|::::  :.|.::||  |.....:|.....
Human   346 SRQELTAHLTNQWPSPGALDVNAVALDTL----LYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLD 406

  Fly   468 P---KKHFGNMNLVFVEERRQQLQIYLLNLVETLPQVEACKSKAELQ 511
            |   ::..|..:.:.|....::....||.|..:|..|.:.||...|:
Human   407 PGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLK 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5439	NP_609607.1	RUN	64..206	CDD:280855	31/148 (21%)
		PX_RUN	404..520	CDD:132810	24/123 (20%)
RUNDC3B	NP_612147.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		RUN	65..203	CDD:397055	32/161 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	399..428		4/28 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4381
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900