Protein Alignment Sfmbt and scml2

DIOPT Version :10

• Sequence 1: NP_001137821.1
• Gene: Sfmbt / 34709
• FlyBaseID: FBgn0032475
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: XP_012812742.2
• Gene: scml2 / 780057
• XenbaseID: XB-GENE-6043728
• Length: 706
• Species: Xenopus tropicalis
• Alignment Length: 803
• Identity: 185/803 - (23%)
• Similarity: 294/803 - (36%)
• Gaps: 226/803 - (28%)

  Fly   541 RLSKENFN-----------AAPVTCFPHA---PGCEVWDNLGVGMKVEVENTDCDSIEVIQPGQT 591
            :.:||.||           |||..||..:   |.    ::..||||:|..:.           :.
 Frog     8 KTAKEKFNWDDYLNQVGSVAAPPNCFKQSRTPPS----NDFKVGMKLEAHDP-----------RN 57

  Fly   592 PTSFWVATILEIKGYKALMSYEGFDTDSHDFWVNLCNAEVHSVGWCATRGKPLIPPRTIEHKYKD 656
            .||..:||::.|.|.:..:..:|.| |.:|||..:.:.::..:|.|..:|..|.||.........
 Frog    58 ITSICIATVVGITGARLRLRLDGSD-DKNDFWRLVDSCDIQQIGTCEKKGDMLQPPLGFRMNASS 121

  Fly   657 WKDFLVGRLSGARTLP-SNFYNKINDSLQSRFRLGLNLECVDKDRISQVRLATVTKIVGKRLFLR 720
            |..||:..|:||...| :.|..:.....||.|:.|:.||.|||.....:..||:..:.|..:|:.
 Frog   122 WPMFLLKTLNGADMAPITCFKQEPQKPSQSFFKTGMKLEAVDKKNPYLICPATIGDVKGDDIFIT 186

  Fly   721 Y------FDSDDGFWCHEDSPIIHPVGWATTVGHNL-----------------AAPQDYLERML- 761
            :      ||    :||..||..|.|:||.:..|.:|                 |:|...:.|.:
 Frog   187 FDGWRGAFD----YWCKYDSRDIFPIGWCSLTGDSLQPPGNSVSLPRTSSTPTASPIKGVRRSMQ 247

  Fly   762 ---------AGREAMIE--VHEDDATIELFK--MNFTFD------EYYSDGKTNSFVEGMKLEAV 807
                     .||:.|.:  :.:..|:....|  .|.|..      |..:..|......|.|.|.:
 Frog   248 SPQKPVQAQKGRKPMRDKCLGQTSASPRKGKRPKNTTLSRNTPNAENQTKSKGTGLKPGRKKETL 312

  Fly   808 DPLNLSSICPATV-------MAVLKFGYMMIRIDSYQPDASGSDWFCYHEKSPCIFPAGFCSVNN 865
             .|| ||:.|...       ..:||.|..::                   .||....:..|.
 Frog   313 -ALN-SSLPPVNTSDGDSNKSQILKDGVGIL-------------------GSPVAVISTVCV--- 353

  Fly   866 ISVTPPNGYDSRTFTWEGYLRDTGAVAAGQHLFHRII---PDH---GFEVGMSLE-----CADLM 919
                              |:...|  .:|.||..:.:   |||   | .|.:.|:     |.|
 Frog   354 ------------------YVNKHG--NSGPHLDKKKVLQLPDHFGPG-PVNVVLQQAVQACVD-- 395

  Fly   920 DPRLVCVATVARVV----------GRLLKVHFDGWTDEYDQWLDCESADIYPVGWCVLVNHKLEG 974
                 | |..:::|          |..:...|||         :..|..:.||.....|...||
 Frog   396 -----C-AYYSKIVFSFLKSGHHGGEAITASFDG---------EKHSVHLPPVNSASFVLRFLE- 444

  Fly   975 PPRVAHQQ------APKPAPKPKIQRKRKPKKGAAGGKTPTDNNTQSVKSRTIALKT-------- 1025
              ::.|..      :.:|.         .|..|  |..:|||.:........|..::
 Frog   445 --KLCHSLQCDNLFSSQPF---------SPHMG--GAHSPTDYDRSKTTKEEITDRSNKRYCQDP 496

  Fly  1026 -------TPHLPKLSIKLELKPEHHNAAFYENNQPEEEGDEEDPDADGDGDGSTSHISEQSTTQS 1083
                   :|.||:..:.   .||...:...||..|:::...|:.........:|:..:.::||:
 Frog   497 PPFSAPLSPKLPRSEVH---PPEAEMSPTEENCMPKDQRFSEESMDSALNTVNTASPATRNTTE- 557

  Fly  1084 SSDLIAGSGSGSGSASLVTLATGSNKTVKKSTTKSPAPPTVGRKATSYIANSSATNNKYIPRLAD 1148
            ..::.|.|....||...||..:.....|::|::.|.:       .:.|..:|.....:.|...:.
 Frog   558 YRNMGATSAYYRGSVQPVTATSNGAPVVRRSSSSSAS-------NSCYYDSSRNRTQRRIEAASS 615

  Fly  1149 IDSSEPH---------LELVPDTWNVYDVSQFLRVNDCTA---HCDTFSRNKIDGKRLLQLTKDD 1201
            ....|.|         |...|.||:|.||..|::..|..|   |.:.|.|::|||..||.|..|.
 Frog   616 TTGPELHSTERQTTQSLSKDPATWSVDDVMCFVKEADPQALAPHAELFRRHEIDGTALLLLRSDM 680

  Fly  1202 IMPLLGMKVGPALKISDLIAQLK 1224
            ||..:|:|:|||||:...|.:||
 Frog   681 IMKYMGLKLGPALKLCYHIERLK 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT_dSfmbt_rpt1	564..672	CDD:439109	29/107 (27%)
		MBT_dSfmbt_rpt2	674..753	CDD:439112	27/101 (27%)
		MBT_dSfmbt_rpt3	798..904	CDD:439115	19/115 (17%)
		MBT_dSfmbt_rpt4	905..976	CDD:439118	19/88 (22%)
		SAM_Scm-like-4MBT	1160..1226	CDD:188979	31/68 (46%)
scml2	XP_012812742.2	MBT	14..143	CDD:459242	39/144 (27%)
		MBT_SCML2_rpt2	148..224	CDD:439099	25/79 (32%)
		RBR	255..316	CDD:465382	14/62 (23%)
		SLED	350..459	CDD:463469	28/152 (18%)
		SAM_Scm	633..704	CDD:188977	31/71 (44%)