Protein Alignment Sfmbt and l3mbtl1b

DIOPT Version :10

• Sequence 1: NP_001137821.1
• Gene: Sfmbt / 34709
• FlyBaseID: FBgn0032475
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: XP_688020.5
• Gene: l3mbtl1b / 559572
• ZFINID: ZDB-GENE-100922-38
• Length: 786
• Species: Danio rerio
• Alignment Length: 1106
• Identity: 239/1106 - (21%)
• Similarity: 370/1106 - (33%)
• Gaps: 405/1106 - (36%)

  Fly   199 MAQMPGSLG-VPGVEHDLLVPL--PDGLLHHKLLGTTLVPAMGTLNGN-------AFGNIMVSTE 253
            ||:...|.| ..|.:.|::..|  .||:              .||.|:       .||.:.:.||
Zfish     1 MAETSVSDGPATGGDFDMMSALDWKDGI--------------ATLPGSDIRFRMTEFGTLEIVTE 51

  Fly   254 ----------------------------NTSSKQMQRTYSTAKGANSTATTATCSASTSSALRSQ 290
                                        ||:|.|      |||..::|....:..|||
Zfish    52 AEPKIKETELTDPQPKITGPINRHPPDLNTTSNQ------TAKIQSNTDHQTSTPAST------- 103

  Fly   291 RKTRKIEPVNRPG---LVLKTPIAYRGNIDPSVIPIQKDGMAVCKRCGAIGVKHTFYTKSRRFCS 352
                  ||..:.|   ..:..||.  ..:..:::|: .:....|:.||..|.:.:|.  ..:|||
Zfish   104 ------EPQRQAGGDSSTVDNPII--NTVPNAIVPV-TEAPINCRTCGLSGSRESFL--QGKFCS 157

  Fly   353 MACARGELYSLVLNTKMEGDQATTSSPDPGAGSESADLPGDQQQSQSDIELDLHAAHIKNANYRF 417
            .:|.:                     |..|..:.:....|::...
Zfish   158 ASCVQ---------------------PSSGRSTPAEAFEGERLGK-------------------- 181

  Fly   418 RITDQSKITQLNSFGEPMSMGGDAAANNVQMAADETIAALNGGAVGDATAPGSTEEGASTPNSYL 482
            |:..:.|:     |.|    ..|....|::                      ..||...:.....
Zfish   182 RVRKKKKM-----FME----SEDEEEENIE----------------------EEEERVKSSKGRR 215

  Fly   483 SAAPTPKALRLFKDIYPQDDLPQIPKYERLPVPCPQMEKIISIRRRMYDPTHSYDWLPRLSKENF 547
            :|    |..||                    |..|.::|            .::.|...|.:|..
Zfish   216 AA----KVARL--------------------VTAPLVKK------------KTWSWSVYLEEERA 244

  Fly   548 NAAPVTCF-PHAPGCEVWDNLGVGMKVEVENTDCDSIEVIQPGQTPTSFWVATILEIKGYKALMS 611
            .|||:..| .|....:..:...||||          :|.:.|.. |..|.|.|:.|::||:..:.
Zfish   245 AAAPLKLFKEHQSFPQSRNGFKVGMK----------LEGLDPCH-PALFCVLTVAEVQGYRIRLH 298

  Fly   612 YEGFDTDSHDFWVNLCNAEVHSVGWCATRGKPLIPPRTIEHKYKDWKDFLV---GRLSGARTLPS 673
            ::|: .:.:|||||..:.:|...|||......|:.|:.......:|..::.   |:|:     |.
Zfish   299 FDGY-PECYDFWVNADSWDVKPPGWCEKTSLKLLLPKGCRDGEFNWNTYVKNCRGQLA-----PK 357

  Fly   674 NFYNKINDSL-QSRFRLGLNLECVDKDRISQVRLATVTKIVGKRLFLRYFDSDD--GFWCHEDSP 735
            :.:..:|.|: .|.||.|:.||.||:..:|.:.:||:...|..||.:.....||  .:||...||
Zfish   358 HLFKSLNTSVTPSGFRAGMKLEAVDRKNLSDICVATIAAAVDNRLLIHIDHCDDTHDYWCDASSP 422

  Fly   736 IIHPVGWATTVGHNLAAPQDYLERMLAGREAMIEVHEDDATIELFKMNFTFDEYYSDGKTNSFVE 800
            .|||||:...|...|..|.:|  :.|.|
Zfish   423 YIHPVGYCEEVKLTLTTPAEY--KHLKG------------------------------------- 448

  Fly   801 GMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDASGSDWFCYHEKSPCIFPAGFCSVNN 865
                                                                             
Zfish   449 ----------------------------------------------------------------- 448

  Fly   866 ISVTPPNGYDSRTFTWEGYLRDTGAVAAGQHLFHRIIPDHGFEVGMSLECADLMDPRLVCVATVA 930
                         |:||.||.:||..||....|.: .|.|||:||:.||..|..:|.|:.|||::
Zfish   449 -------------FSWEKYLEETGTQAAPARAFKQ-RPPHGFQVGVKLEAVDKRNPMLIRVATIS 499

  Fly   931 RVVGRLLKVHFDGWTDEYDQWLDCESADIYPVGWCVLVNHKLEGPPRVAHQQAPKPAPKPKIQRK 995
            ......:|:|||||:||||.|||.:|.:::|||||....|.|:      |....:.:|.|..|
Zfish   500 DTEEHRIKIHFDGWSDEYDYWLDADSPELHPVGWCQKTGHPLQ------HPNGTRDSPVPPGQ-- 556

  Fly   996 RKPKKGAAGGKTPTDNNTQSVKSRTIALKTT----PH----------LP-KLS----IKLELKPE 1041
                    |..||..|....::........|    |:          :| :||    :.:...|.
Zfish   557 --------GCPTPGCNGVGHIRGPRYGTHYTAVSCPYSDLNFNKDGLVPDRLSGERPVTISGPPR 613

  Fly  1042 HHNA-AFYENNQPEEEGD-EEDPDADGDGDGSTSHISEQSTTQSSSDLIAGSGSGSGSASLVTLA 1104
            |..| ...:.:||..... .|.||...|.......:.|...|.::.
Zfish   614 HRRAETLTQTHQPTSSASTPEPPDTTTDACPQARPVREHVVTAAAP------------------- 659

  Fly  1105 TGSNKTVKKSTTKSPAPPTVGRKATSYIANSSATNNKYIPRLADIDSSEPHLELVPDT------- 1162
                |.||....|....   |:.:.....:.|.......||..  ...|.|.:|:|:.
Zfish   660 ----KCVKAPQVKQEGD---GKDSLQQFLHESVFCGWEQPRFQ--LCWEKHGKLLPEALGLTAKR 715

  Fly  1163 ---WNVYDVSQFLR-VNDCTAHCDTFSRNKIDGKRLLQLTKDDIMPLLGMKVGPALKISDLIAQL 1223
               ||..:|:.|:| :..|..|..||.:.:|||:..|.||:.||:.:|.:|:||||||.:.|..|
Zfish   716 VSKWNTEEVASFVRGLPGCREHAPTFRKEQIDGEAFLLLTQSDIVKILSIKLGPALKIYNSILML 780

  Fly  1224 K 1224
            |
Zfish   781 K 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT_dSfmbt_rpt1	564..672	CDD:439109	28/110 (25%)
		MBT_dSfmbt_rpt2	674..753	CDD:439112	29/81 (36%)
		MBT_dSfmbt_rpt3	798..904	CDD:439115	10/105 (10%)
		MBT_dSfmbt_rpt4	905..976	CDD:439118	34/70 (49%)
		SAM_Scm-like-4MBT	1160..1226	CDD:188979	29/76 (38%)
l3mbtl1b	XP_688020.5	MBT	260..360	CDD:459242	29/116 (25%)
		MBT	367..459	CDD:459242	36/208 (17%)
		MBT_L3MBTL1-like_rpt3	472..544	CDD:439093	35/77 (45%)
		zf-C2HC	558..586	CDD:460240	5/27 (19%)
		SAM_Scm-like-3MBT3,4	716..781	CDD:188981	26/64 (41%)