DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sfmbt and ph-d

DIOPT Version :9

Sequence 1:	NP_001137821.1	Gene:	Sfmbt / 34709	FlyBaseID:	FBgn0032475	Length:	1243	Species:	Drosophila melanogaster
Sequence 2:	NP_524794.2	Gene:	ph-d / 44889	FlyBaseID:	FBgn0004860	Length:	1537	Species:	Drosophila melanogaster

Alignment Length:	299	Identity:	62/299 - (20%)
Similarity:	116/299 - (38%)	Gaps:	53/299 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   967 LVNHKLEGPPRVAHQQAPKPAPKPKIQRKRKPKKGAAGGKTPTDNNTQSVKSRTIALKTTP---- 1027
            ::.|.::|   ...|:|.:|.|   :.|:|...|..: .:.|....|.....:...:.:.|
  Fly  1253 VLTHVIDG---FIIQEANEPFP---VTRQRYADKDVS-DEPPKKKATMQEDIKLSGIASAPGSDM 1310

  Fly  1028 ----HLPKLSIKLELKPEHHNAAFYENNQPEEEGDEEDPDADGDGDGSTSHISEQSTTQSSSDLI 1088
                ...|:..|.:||.:.:.:...........|.....:.:|.|.|....:...:......:.:
  Fly  1311 VACEQCGKMEHKAKLKRKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAM 1375

  Fly  1089 AGSGSGSGSASLVTLATGSNKTVKKSTTKSPAPPTVGRKATSYIANSSATNNKYIPRLADID-SS 1152
            |..          .:.|.|.:||..:.....|.|.|...:...:|..|.::...:|....:. :.
  Fly  1376 AEE----------KMQTESYQTVSDALPIQAATPEVPPISMPVLAAMSTSSPLSLPLTLPLPIAI 1430

  Fly  1153 EPHLEL-------------VP------------DTWNVYDVSQFLR-VNDCTAHCDTFSRNKIDG 1191
            .|.:.|             :|            .:|:|.:||.|:| :..|..:.|.|.:.:|||
  Fly  1431 APTVSLPVVSAGVVAPVLAIPSSNINGSDRPPISSWSVEEVSNFIRELPGCQDYVDDFIQQEIDG 1495

  Fly  1192 KRLLQLTKDDIMPLLGMKVGPALKISDLIAQLKCKVNPG 1230
            :.||.|.::.::..:|||:||||||...:..:| :|.||
  Fly  1496 QALLLLKENHLVNAMGMKLGPALKIVAKVESIK-EVPPG 1533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT	542..647	CDD:214723
		MBT	658..753	CDD:214723
		MBT	767..871	CDD:214723
		MBT	882..975	CDD:214723	1/7 (14%)
		TonB_N	<975..1040	CDD:292650	13/72 (18%)
		SAM_Scm-like-4MBT	1160..1226	CDD:188979	26/78 (33%)
		SAM	1160..1224	CDD:197735	25/76 (33%)
ph-d	NP_524794.2	SAM_Ph1,2,3	1461..1529	CDD:188976	25/68 (37%)
ph-d	NP_524794.2	SAM	1464..1529	CDD:197735	25/65 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840