Protein Alignment Sfmbt and L3mbtl1

DIOPT Version :10

• Sequence 1: NP_001137821.1
• Gene: Sfmbt / 34709
• FlyBaseID: FBgn0032475
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: XP_017447769.1
• Gene: L3mbtl1 / 311613
• RGDID: 1307316
• Length: 884
• Species: Rattus norvegicus
• Alignment Length: 933
• Identity: 212/933 - (22%)
• Similarity: 331/933 - (35%)
• Gaps: 287/933 - (30%)

  Fly   372 DQATTSSPDPGAGSESADL-PGDQ-----QQSQSDIELD-------LHAAHIKNANYRFRITDQS 423
            |....|:|..|:|...::| |..|     ..:|:.||::       .|...........:..|..
  Rat   152 DWTGVSAPLAGSGMRPSELGPASQFRINEYATQNMIEIERPRSPEQRHEGGTAGREADIQHPDVH 216

  Fly   424 KITQLNSFGE--PMSMGGDAAANNVQMAADETIAALNGGAVGDATAPGSTEEGASTPNSYLSAAP 486
            |..|     |  |.....||.:...|....:....|:.|:.||.......:......||..:.|.
  Rat   217 KDPQ-----EVIPQEPSVDAGSCKCQTCGPQQSIGLDVGSSGDRCPQPFQKRSVIVENSGCTVAS 276

  Fly   487 ---TPKALRLFKDIY--PQDDLPQIPKY------ERLPVPCP------QMEKIISIRRRMYDPTH 534
               .|...|..|:..  .::..|:..|.      :|.|.|..      ...:::|..::     .
  Rat   277 ELIKPMKKRKHKEYQSPSEESEPEAMKQGKGKDPDREPTPGTSENEEWSRSQLVSSEKK-----E 336

  Fly   535 SYDWLPRLSKENFNAAPVTCFPHAPGCEVWDN-LGVGMKVEVENTDCDSIEVIQPGQTPTSFWVA 598
            .:.|...|.::....|||:.|..:.......| ..:|||          :|.:.| |.|:.::|.
  Rat   337 GWSWESYLEEQKAVTAPVSLFQDSQAVTHNKNGFKLGMK----------LEGVDP-QHPSMYFVL 390

  Fly   599 TILEIKGYKALMSYEGFDTDSHDFWVNLCNAEVHSVGWCATRGKPLIPPRTIEHKYKDWKDFLVG 663
            |:.|:.||:..:.::|: ::.||||||..:.::|..||....|..|.||:..:.:...|..:|
  Rat   391 TVAEVCGYRLRLHFDGY-SECHDFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYL-- 452

  Fly   664 RLSGARTLPSN-FYNKINDSLQSRFRLGLNLECVDKDRISQVRLATVTKIVGKRLFLRYFDSDD- 726
            |.:.|:..|.: |.::.:......|::|:.||.||:...|.|.:|:||.:|..|..:.:.|.||
  Rat   453 RSTKAQAAPKHLFVSQSHSPPPVGFQVGMKLEAVDRMNPSLVCVASVTDVVASRFLVHFDDWDDT 517

  Fly   727 -GFWCHEDSPIIHPVGWATTVGHNLAAPQDYLERMLAGREAMIEVHEDDATIELFKMNFTFDEYY 790
             .:||...||.||||||....|..|..||||
  Rat   518 YDYWCDASSPYIHPVGWCQKQGKPLTPPQDY---------------------------------- 548

  Fly   791 SDGKTNSFVEGMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDASGSDWFCYHEKSPCI 855
                                                           ||
  Rat   549 -----------------------------------------------PD---------------- 550

  Fly   856 FPAGFCSVNNISVTPPNGYDSRTFTWEGYLRDTGAVAAGQHLFHRIIPDHGFEVGMSLECADLMD 920
             |..||                   ||.||.:||..|.....| ::.|.|.|.|.|.||..|..:
  Rat   551 -PDSFC-------------------WEKYLEETGTSAVPTWAF-KVRPPHSFLVNMKLEAVDRRN 594

  Fly   921 PRLVCVATVARVVGRLLKVHFDGWTDEYDQWLDCESADIYPVGWCVLVNHKLEGPPRVAHQQAPK 985
            |.|:.||:|..|....:|:|||||:..||.|:|.:..||:|.|||....|.||.|.|.....:..
  Rat   595 PALIRVASVEDVEDHRIKLHFDGWSHNYDFWIDADHPDIHPAGWCSKTGHPLEPPLRPRESSSAS 659

  Fly   986 PAPKPKIQRKRKPKKGAAGGKTPTDNNTQSVKSRTIALKTTPHLPKLSIKLELKPEHHNAAFYEN 1050
            |...|.:..:..|.                       .||:.:                 :|:..
  Rat   660 PGGCPPLSHRSPPH-----------------------TKTSKY-----------------SFHHR 684

  Fly  1051 NQPEEEGDEEDPDADGDGDGS---TSH-------ISEQSTTQSSSDLIAGSGSGSGSASLVTLAT 1105
            ..|       .|..||.|..:   |:|       ::|::.::..::|       |.|.:......
  Rat   685 KCP-------TPGCDGSGHVTGKFTAHHCLSGCPLAERNQSRLKAEL-------SDSETTARKKN 735

  Fly  1106 GSNKTVKKST------------TKSP------APPTVGRKATSYIANSSATNNKYIPRLADIDSS 1152
            .||.:.:|..            .|.|      .||:|..::. :::.        :|..||...|
  Rat   736 QSNLSPRKKPRHQGRIGRPPKYRKMPDEDFQALPPSVVHQSL-FMST--------LPTHADRPLS 791

  Fly  1153 ---EPHLELVP----------DTWNVYDVSQFLRVNDCTAHCD---TFSRNKIDGKRLLQLTKDD 1201
               |.|.:|:|          ..|.:.:|..|  |...|...|   .|....|||:..|.||:.|
  Rat   792 VCWEQHCKLLPGVAGISASAVSKWTIEEVFGF--VQTLTGSEDQARLFKEEMIDGEAFLLLTQAD 854

  Fly  1202 IMPLLGMKVGPALKISDLIAQLK 1224
            |:.::.:|:||||||.:.|...|
  Rat   855 IVKIMSVKLGPALKIYNAILMFK 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT_dSfmbt_rpt1	564..672	CDD:439109	31/108 (29%)
		MBT_dSfmbt_rpt2	674..753	CDD:439112	29/81 (36%)
		MBT_dSfmbt_rpt3	798..904	CDD:439115	13/105 (12%)
		MBT_dSfmbt_rpt4	905..976	CDD:439118	32/70 (46%)
		SAM_Scm-like-4MBT	1160..1226	CDD:188979	25/78 (32%)
L3mbtl1	XP_017447769.1	MBT_L3MBTL1_rpt1	357..465	CDD:439121	33/121 (27%)
		MBT	472..564	CDD:459242	41/208 (20%)
		MBT_L3MBTL1_rpt3	577..651	CDD:439127	34/73 (47%)
		zf-C2HC	685..713	CDD:460240	7/34 (21%)
		SAM_Scm-like-3MBT3,4	812..877	CDD:188981	23/66 (35%)