Protein Alignment Sfmbt and Sfmbt2

DIOPT Version :10

• Sequence 1: NP_001137821.1
• Gene: Sfmbt / 34709
• FlyBaseID: FBgn0032475
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: NP_001100834.2
• Gene: Sfmbt2 / 307106
• RGDID: 1305027
• Length: 890
• Species: Rattus norvegicus
• Alignment Length: 888
• Identity: 210/888 - (23%)
• Similarity: 320/888 - (36%)
• Gaps: 248/888 - (27%)

  Fly   536 YDWLPRLSKENFNAAPVTCFPHAPGCEVWDNLGVGMKVEVENTDCDSIEVIQPGQTPTSFWVATI 600
            :.|...|.:....|.|..||.|.. ..:..|...|||:||.|.:           .|.::|||||
  Rat    43 FSWGDYLDETGARAVPHVCFRHVE-ISIQSNFQPGMKLEVANKN-----------HPDTYWVATI 95

  Fly   601 LEIKGYKALMSYEGFDTDSH-DFWVNLCNAEVHSVGWCATRGKPLIPPRTIEHKYKDWKDFLVGR 664
            :...|...|:.|.|:..|.. |||.::..|::|.||||....|.|.||..|:.||.||::||:..
  Rat    96 ITTCGQLLLLRYCGYGEDRRADFWCDVIIADLHPVGWCTQNNKVLRPPDAIKEKYADWEEFLIHE 160

  Fly   665 LSGARTLPSNFYNKINDSLQSRFRLGL-----NLECVDKDRISQVRLATVTKIVGKRLFLRYF-- 722
            |:|:||.|::.   :...|:.:..:.|     .:|..|.....|..:.:|.:.||.||.|||.
  Rat   161 LTGSRTAPASL---LEGPLRGKGPIDLITVDSLIELQDSQNPFQYWIVSVIENVGGRLRLRYVGL 222

  Fly   723 ---DSDDGFWCHEDSPIIHPVGWATTVGHNLAAPQD--YL----ERMLAGREAMIEVHEDDATIE 778
               :|.|.:..:.|.. :.|:||.....:.:..|.:  ||    |...|..:|::...|....:|
  Rat   223 EHTESYDRWLFYLDYR-LRPIGWCQEKKYRMDPPSELYYLKLPFEWKCALEKALLAAAECPLPME 286

  Fly   779 LFKMNFTFDEYYSDGKTNSFVEGMKLEAV---DPLNLSSICPATVMAVLKFGYMMIRIDSYQPDA 840
            :||       .::|..::.|..||:||.:   ||.:   |.||||..|....:..:.||..:.:.
  Rat   287 VFK-------DHADLGSHFFTVGMRLETLHINDPFH---IYPATVTKVFNSQFFQVAIDDLRAET 341

  Fly   841 SGSDWFCYHEKSPCIFPAGFCSVNNISVTPPNGYDSRTFTWEGYLRDTGAVAAGQHLFHRIIPDH 905
            :|....| |..|..|.|..:|..|.:::.||.||..:.|.|..|.:...|..|..:.|..... .
  Rat   342 NGLTMLC-HADSLGILPVQWCLKNGVNLAPPKGYSGQDFNWVDYHKQREAEGAPPYCFKNTFA-R 404

  Fly   906 GFEVGMSLECADLMDPRLVCVATVARVVGRLLKVHFDG-WTDEYDQWLDCESADIYPVGWCVLVN 969
            ||...|.||..:..:|..||||||..|.|.||.:..:| .|...:..:|.:|.||:|||||...:
  Rat   405 GFAKNMKLEAVNPKNPGEVCVATVISVRGSLLWLRLEGVETPMPEIIVDIDSMDIFPVGWCEANS 469

  Fly   970 HKLEGPPRVAHQQAPKPAPKPKIQRKRKP------------------KKGAAGGK---------- 1006
            :.|..|.:.:.:...||...|..:....|                  ..|||..|
  Rat   470 YPLTTPYKSSSKSKKKPITVPPEKPSLPPVPVENIPQELCLPPQTDTAAGAANEKYYCPQLFVNH 534

  Fly  1007 ---------------------------------TPTDNNTQS----------------------- 1015
                                             |...|....
  Rat   535 RCFSGPFLNKGRISELPQSVGPGKCVLVLKEILTMITNAAYKPGRVLRELQLVEDPEWDFQEEVL 599

  Fly  1016 ------------VKSRTIALKTTPHLPKLSIKLELKPEHHNAAFYENNQPE-------------- 1054
                        ||....|.:.|....::..|||..|...:......|.||
  Rat   600 KAKYRGKIYRAVVKIVRTADQVTSFCQQVCAKLECCPNLFSPLLISENCPENCSIRTKTKYTYYY 664

  Fly  1055 --------------------------------------------------EEGDEEDPDADGDGD 1069
                                                              :|.:|:||:|.....
  Rat   665 GKRKRIIKPPLGESNTESAPKPTRRRKRRKSIYVQKKRKSSAVAMPATSAQETEEDDPEALDTAS 729

  Fly  1070 GSTSHISEQSTTQ----------SSSDLIAGSGSGSGSASLVTLATGSNKTVKKSTTKSPAPPTV 1124
            ..|.::.:...||          |...:|....||:                    .|.| |...
  Rat   730 EETGYVVQNYKTQHVPVEMPFTRSQRAMILRKHSGA--------------------VKHP-PVER 773

  Fly  1125 GRKATSYIANSSATNNKYIPRLADIDSSEPH--------LELVPDTWNVYDVSQFLRVNDCTAHC 1181
            .|:..|..:.:|:.|...:|.:....|.:|.        ||..|..|:|.||.:|:::.||....
  Rat   774 ARRVRSVHSTASSNNRNKVPLVRIEKSEDPRQSEEEKLILESNPLEWSVTDVVRFIKLTDCAPLA 838

  Fly  1182 DTFSRNKIDGKRLLQLTKDDIMPLLGMKVGPALKISDLIAQLK 1224
            ..|....|||:.||.||...:...:.:|:|||:|:...|.::|
  Rat   839 RIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERVK 881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT_dSfmbt_rpt1	564..672	CDD:439109	42/108 (39%)
		MBT_dSfmbt_rpt2	674..753	CDD:439112	19/88 (22%)
		MBT_dSfmbt_rpt3	798..904	CDD:439115	33/108 (31%)
		MBT_dSfmbt_rpt4	905..976	CDD:439118	28/71 (39%)
		SAM_Scm-like-4MBT	1160..1226	CDD:188979	23/65 (35%)
Sfmbt2	NP_001100834.2	MBT_SFMBT2_rpt1	70..163	CDD:439102	39/103 (38%)
		MBT	182..269	CDD:459242	22/87 (25%)
		MBT_SFMBT2_rpt3	297..389	CDD:439106	30/95 (32%)
		MBT	405..493	CDD:459242	32/87 (37%)
		SLED	527..641	CDD:463469	10/113 (9%)
		SAM_Scm-like-4MBT1,2	807..890	CDD:188980	25/75 (33%)