Protein Alignment Sfmbt and L3mbtl2

DIOPT Version :10

• Sequence 1: NP_001137821.1
• Gene: Sfmbt / 34709
• FlyBaseID: FBgn0032475
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: XP_008763933.1
• Gene: L3mbtl2 / 300320
• RGDID: 1308569
• Length: 728
• Species: Rattus norvegicus
• Alignment Length: 809
• Identity: 285/809 - (35%)
• Similarity: 397/809 - (49%)
• Gaps: 183/809 - (22%)

  Fly   252 TENT-SSKQMQRT----------YSTAKGANSTATTATCS--ASTSSALRSQRKTRKIEPVNRPG 303
            ||.| ||:.|:..          |.:.:..||:|.:.:.|  ..:|.|....|:.         |
  Rat     7 TEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSAGSESSSYLEESSEAENEDREA---------G 62

  Fly   304 LVLKTPIAYRGNIDPSVIPIQKDGMAVCKRCGAIGVKHTFYTKSRRFCSMACARGELYSLVLNTK 368
            .:..:|:....:.:...:.......|||:.||.:|.:..|::|::||||::|:|.  ||  .|:|
  Rat    63 ELPTSPLHLFSSANNRALDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRS--YS--SNSK 123

  Fly   369 MEGDQATTSSPDPGAGSESADLPGDQQQSQSDIELDLHAAHIKNANYRFRITDQSKITQLNSFGE 433
            .....|......|                                      |.::|:..
  Rat   124 KASILARLQGKPP--------------------------------------TKKAKVLH------ 144

  Fly   434 PMSMGGDAAANNVQMAADETIAALNGGAVGDATAPGSTEEGASTPNSYLSAAPTPKALRLFKDIY 498
                   .||.:.::.|  .:.|...|.:.|.|..|
  Rat   145 -------KAAWSAKIGA--FLHAQGTGQLADGTPTG----------------------------- 171

  Fly   499 PQDDLPQIPKYERLPVPCPQMEKIISIRRRMYDPTHSYDWLPRLSKENFNAAPVTCFPHAPGCEV 563
             ||.|                             ...:||...|...::.||||.||.|.|..:.
  Rat   172 -QDAL-----------------------------VLGFDWGKFLKDHSYKAAPVGCFKHVPLYDQ 206

  Fly   564 WDNLGVGMKVEVENTDCDSIEVIQPGQTPTSFWVATILEIKGYKALMSYEGFDTD-SHDFWVNLC 627
            |:::..||||||.|:|     .:.|.:.   :|:||:::..||:.|:.||||:.| |||||.||.
  Rat   207 WEDVMKGMKVEVLNSD-----AVLPSRV---YWIATVIQAAGYRVLLRYEGFENDASHDFWCNLG 263

  Fly   628 NAEVHSVGWCATRGKPLIPPRTIEHKYKDWKDFLVGRLSGARTLPSNFYNKINDSLQSRFRLGLN 692
            ..:||.:||||...|.|:|||||..|:.|||.:|:.||.|:||||::|:.|:.:|::..||.|:.
  Rat   264 TVDVHPIGWCAINSKILVPPRTIHAKFTDWKSYLMKRLVGSRTLPADFHIKMVESMKYPFRQGMR 328

  Fly   693 LECVDKDRISQVRLATVTKIVGKRLFLRY--FDSDDGFWCHEDSPIIHPVGWATTVGHNLAAPQD 755
            ||.|||.::|:.|:|.|..::|.||.|.|  .||||.||||..||:||||||:..|||.:
  Rat   329 LEVVDKTQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGI----- 388

  Fly   756 YLERMLAGREAMIEVHED------DATIELFKMNFTFDEYYSDGKTNSFVEGMKLEAVDPLNLSS 814
                .::.|...:..|..      ||...|||   .....|::|  ..|.|||||||:|||||.:
  Rat   389 ----KMSERRCDMSHHPTFRKIYCDAVPYLFK---KVRAVYTEG--GWFEEGMKLEAIDPLNLGN 444

  Fly   815 ICPATVMAVLKFGYMMIRIDSYQPDASGSDWFCYHEKSPCIFPAGFCSVNNISVTPPNGYDSRTF 879
            ||.||:..||..||:||.:|. .|...||||||||..|..||||.||..|:|.:|||.||:::.|
  Rat   445 ICVATICKVLLDGYLMICVDG-GPSTDGSDWFCYHASSHAIFPATFCQKNDIELTPPKGYETQPF 508

  Fly   880 TWEGYLRDTGAVAAGQHLFHRIIPDHGFEVGMSLECADLMDPRLVCVATVARVVGRLLKVHFDGW 944
            .||.||..|.:.||...||:...|:|||:|||.||..|||:|||:|||||.|||.|||.:|||||
  Rat   509 DWESYLEKTKSKAAPARLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGW 573

  Fly   945 TDEYDQWLDCESADIYPVGWCVLVNHKLEGPPRVAHQQAPKPAPKPKIQRKRKPKK-GAAGGKTP 1008
            .:|||||:||||.||||||||.|..::|: ||..|....|:   |.|...|:|.|: |....:.|
  Rat   574 DNEYDQWVDCESPDIYPVGWCELTGYQLQ-PPVSAEPNTPQ---KGKDATKKKKKQFGKKRKRIP 634

  Fly  1009 TDNNTQSVKSRTIALKTTPHLPKLSIKLE 1037
            :        ::|..|:.:...|.|...||
  Rat   635 S--------AKTRPLRQSSKKPLLEDNLE 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT_dSfmbt_rpt1	564..672	CDD:439109	51/108 (47%)
		MBT_dSfmbt_rpt2	674..753	CDD:439112	39/80 (49%)
		MBT_dSfmbt_rpt3	798..904	CDD:439115	57/105 (54%)
		MBT_dSfmbt_rpt4	905..976	CDD:439118	49/70 (70%)
		SAM_Scm-like-4MBT	1160..1226	CDD:188979
L3mbtl2	XP_008763933.1	MBT_L3MBTL2_rpt1	207..308	CDD:439111	51/108 (47%)
		MBT_L3MBTL2_rpt2	310..393	CDD:439114	39/91 (43%)
		MBT_L3MBTL2_rpt3	428..518	CDD:439117	52/90 (58%)
		MBT_dSfmbt-like_rpt4	534..604	CDD:439090	49/70 (70%)