DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sfmbt and SCML4

DIOPT Version :9

Sequence 1:	NP_001137821.1	Gene:	Sfmbt / 34709	FlyBaseID:	FBgn0032475	Length:	1243	Species:	Drosophila melanogaster
Sequence 2:	XP_016866166.1	Gene:	SCML4 / 256380	HGNCID:	21397	Length:	442	Species:	Homo sapiens

Alignment Length:	172	Identity:	52/172 - (30%)
Similarity:	73/172 - (42%)	Gaps:	26/172 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1069 DGSTSHISEQSTTQSSSDLIA---GSGS---GSGSASLVTLATGSNKTVKKSTTKSPAPP----- 1122
            |.|.|..:.:.:...||.|..   .||.   |.|.|     ||.........::..|:.|
Human   277 DTSASTFNHRGSLHPSSSLYCKRQNSGDSHLGGGPA-----ATAGGPRTSPMSSGGPSAPGLRPP 336

  Fly  1123 --TVGRKATSYIANSSATNNKYIPRLADIDSSEPHLELVPDTWNVYDVSQFLRVNDCTA---HCD 1182
              :..|..||...|..|::    |.....|:..|. ...|..|.|.||..|::..|..|   |.:
Human   337 ASSPKRNTTSLEGNRCASS----PSQDAQDARRPR-SRNPSAWTVEDVVWFVKDADPQALGPHVE 396

  Fly  1183 TFSRNKIDGKRLLQLTKDDIMPLLGMKVGPALKISDLIAQLK 1224
            .|.:::|||..||.|..|.:|..||:|:|||||:...|.:||
Human   397 LFRKHEIDGNALLLLKSDMVMKYLGLKLGPALKLCYHIDKLK 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT	542..647	CDD:214723
		MBT	658..753	CDD:214723
		MBT	767..871	CDD:214723
		MBT	882..975	CDD:214723
		TonB_N	<975..1040	CDD:292650
		SAM_Scm-like-4MBT	1160..1226	CDD:188979	29/68 (43%)
		SAM	1160..1224	CDD:197735	27/66 (41%)
SCML4	XP_016866166.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149813
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3766
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740