Protein Alignment Sfmbt and Scm

DIOPT Version :10

• Sequence 1: NP_001137821.1
• Gene: Sfmbt / 34709
• FlyBaseID: FBgn0032475
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: XP_061499386.1
• Gene: Scm / 1269174
• VectorBaseID: AGAMI1_002092
• Length: 1089
• Species: Anopheles gambiae
• Alignment Length: 1262
• Identity: 252/1262 - (19%)
• Similarity: 403/1262 - (31%)
• Gaps: 437/1262 - (34%)

  Fly   172 NEDNNSYD-------GTDFMTSSDKDISQSSSSCMAQMPGSLGVPGVEHDLLVPLPDGLLHHKLL 229
            |.:||:.|       .:...|:..|.::.||||..:...|:   .||.|
Mosquito    49 NNNNNNEDSPKSSSVSSSTKTNDRKSVNSSSSSSSSTEEGT---KGVTH---------------- 94

  Fly   230 GTTLVPAMGTLNGNAFGNIMVSTENTSSKQMQRTYSTAKGANSTATTATCSASTSSALRSQRKTR 294
             |.:..::..|:....||                .|:...::.:..|..|.....:.|.|..|
Mosquito    95 -TVVAKSIKRLSDGTGGN----------------NSSVSSSSGSIATIVCKTEDPNLLSSGSK-- 140

  Fly   295 KIEPVNRPG-------LVLKTPIAYRGNIDPSVIPIQKDGMAVCKRCGAIGVKHTFYTKSRRFCS 352
                 ..||       |.:|:|:.|       |:|:|             |:|       :.|||
Mosquito   141 -----GVPGAQTCGWCLEVKSPLNY-------VLPMQ-------------GIK-------KEFCS 173

  Fly   353 MACARGELYSLVLNTKME-GDQATTSSPDPGAGS-------ESADLPGDQQQSQSDIELDLHAAH 409
            .:|.. |...|...|.:: |:....::|.|...|       :.....|..|.::     ||.|..
Mosquito   174 ESCIM-EYRKLSKRTCIQCGNVVRANAPKPNFCSTFCLKKYQKKRAAGLLQPTE-----DLVANG 232

  Fly   410 IKNANYRFRITDQSKITQLNSFGEPMSMGGDAAANNVQMAADETIAALNGGAVGDATAPGSTEEG 474
            ..|.|......:.:.....||.....|.|..                 |||: |..:..|.....
Mosquito   233 STNNNNNVSSHNHNNNNSSNSSTNTPSNGSS-----------------NGGS-GRRSQGGGGNLS 279

  Fly   475 ASTPNSYLSAAPTPKALRLFKDIYPQDDLPQIPKYERLPVPCPQMEKIISIRRRMYDPTHSYDWL 539
            ...|.:..||.||.:.                     .||...|....      .|:..|.:||.
Mosquito   280 PGRPATERSAQPTSRI---------------------SPVTTTQTGAF------QYESFHVFDWS 317

  Fly   540 PRLSKENFNAAPVTCFPHA---PGCEVWDNLGVGMKVEVENTDCDSIEVIQPGQTPTSFWVATIL 601
            ..|.:.....||..||..|   |..|    ..:.||          :|.:.| :..||..:||::
Mosquito   318 EYLRESGSVPAPAECFKQALIPPKNE----FKINMK----------LEALDP-RNITSTCIATVV 367

  Fly   602 EIKGYKALMSYEGFDTDSHDFWVNLCNAEVHSVGWCATRGKPLIPPRTIEHKYKDWKDFLVGRLS 666
            .:.|.:..:..:|.| :.:|||..:.:.|:|.:|.|...|:.|.||.........|..||...|:
Mosquito   368 GVLGSRLRLRLDGGD-NKNDFWRLVDSNEIHPIGHCERSGEMLKPPLGFRLNASSWPTFLSKTLN 431

  Fly   667 GARTLPSNFY------NKINDSLQSRFRLGLNLECVDKDRISQVRLATVTKIVGKRLFLRY---- 721
            ||...|::.:      .|.|     .|::|..||.|||.....:..|||.::...::.:.:
Mosquito   432 GAVMAPADIFVPEPPTPKCN-----LFQVGQKLEAVDKKNPQLICCATVNEVKDDQIHVTFDGWR 491

  Fly   722 --FDSDDGFWCHEDSPIIHPVGWATTVGHNLAAP--QDYLE----RMLAGREAMIEVHEDDATIE 778
              ||    :||..||..|.||||..:..|.:..|  ::.|:    |..|||.:...|.:...|::
Mosquito   492 GAFD----YWCRYDSRDIFPVGWCASSCHPMQPPGQKNKLDGSGHRSKAGRSSFAMVSDSPDTMQ 552

  Fly   779 LFKMNFTFDEYYSDGKTNSFVEGMKL----EAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPD 839
              ........::|..:....:...||    .|.:...|:.:|...|:|
Mosquito   553 --PATLVTAHFHSRCRGGPHINSSKLPSMVTAPNHQTLAKLCLQEVLA----------------- 598

  Fly   840 ASGSDWFCYHEKSPCIFPAGFCSVNNISVTPPNGYDSRTFTWE--GYLRDTGAVAAGQHLFHRII 902
            ||       |:.| .:.|..|....::.:....|   :.||.:  .|::........:.|
Mosquito   599 AS-------HDHS-LLSPLLFGLEGDVHIVTAAG---KNFTVKIPAYIKQKANAGVSEFL----- 647

  Fly   903 PDHGFEVGMSLECADLMD-PRLVCVATVARVVGRLLKVHFDGWTDEYDQWLDCESADIYPVGWCV 966
                     .:.|..... |||:.:.....                     .||...::.:.
Mosquito   648 ---------EMLCTSCQACPRLITLEPGPE---------------------QCEDCSLHSLP--- 679

  Fly   967 LVNHKLEGPPRVAHQQAPKP--APKPKIQRKRKPKKGA----AGGKTPTDNNTQ----SVKSRTI 1021
             :...::..||.|...:|.|  |..||.....:...|.    .|.::..|.:|.    |.|.|.:
Mosquito   680 -LKRSIKTEPRAAAAASPPPTAASSPKASATGRSSAGGHELRPGKESAKDRDTHLRSPSPKRRAV 743

  Fly  1022 ALKTTPHLPKLSIKLELKPEHHNAAFYENNQPEEEG--------DEEDPDADGDGDGSTSHISEQ 1078
            |        ..|...|.|....||.....:.....|        :..:|.:.     :||..|::
Mosquito   744 A--------SSSSSSESKAAGRNAEERSRSPTSSSGATPQSTKKERNEPSSP-----ATSTASKE 795

  Fly  1079 ---STTQSSSDLIAGSGSGSGSASL--------------VTLATGSNKTVKKSTTKSPAP----- 1121
               :||::...:.|.:.|||.||.|              .|:||.|.....||:|.:..|
Mosquito   796 TAATTTETIVKITANTNSGSRSAKLEMSQNQPQPSTTTVTTMATSSTVNQHKSSTAATTPVSQPV 860

  Fly  1122 -----PTVGRKATSYIANSSATNNKY--------------------------------------- 1142
                 .|||..:......:|.|..|.
Mosquito   861 SLASVSTVGSNSKPLTTPTSTTTIKVEVQTGSTVGVGAAQATAAVAATATMPVPAGPAAVPYHPA 925

  Fly  1143 --------------------------------------IPRLADIDSSEPHL------------- 1156
                                                  .|.:|:...:.||.
Mosquito   926 SIVSPLVPGACTLGPAAVAMTSVPGSLIPVVAPASSTPFPTMANAAPTGPHACANTGGVGMGAYF 990

  Fly  1157 ------------ELVPDT----------WNVYDVSQFLRVND--CTAHCDTFSRNKIDGKRLLQL 1197
                        ..||.|          |.:.||.||:.|.|  ...|.:.|.:::||||.||.|
Mosquito   991 ATAPPTLVPSVPSFVPATPQMPRGPTTDWTIEDVIQFIAVQDPSLAIHAELFRKHEIDGKALLLL 1055

  Fly  1198 TKDDIMPLLGMKVGPALKISDLIAQLK 1224
            ..|.:|..:|:|:||||||.:|::::|
Mosquito  1056 NSDMMMKYMGLKLGPALKICNLVSRVK 1082

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT_dSfmbt_rpt1	564..672	CDD:439109	28/107 (26%)
		MBT_dSfmbt_rpt2	674..753	CDD:439112	24/90 (27%)
		MBT_dSfmbt_rpt3	798..904	CDD:439115	18/111 (16%)
		MBT_dSfmbt_rpt4	905..976	CDD:439118	6/71 (8%)
		SAM_Scm-like-4MBT	1160..1226	CDD:188979	30/77 (39%)
Scm	XP_061499386.1	None