DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sfmbt and Scml2

DIOPT Version :9

Sequence 1:	NP_001137821.1	Gene:	Sfmbt / 34709	FlyBaseID:	FBgn0032475	Length:	1243	Species:	Drosophila melanogaster
Sequence 2:	XP_006528733.1	Gene:	Scml2 / 107815	MGIID:	1340042	Length:	1136	Species:	Mus musculus

Alignment Length:	442	Identity:	113/442 - (25%)
Similarity:	156/442 - (35%)	Gaps:	126/442 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   788 EYYSDGK---TNSFVEGMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDASGSD----- 844
            ||:...|   ||.|..||||||.||.|:.|:|.|:|:.:.. ..:.:|:|       |||
Mouse   167 EYFRQSKTPPTNEFKIGMKLEARDPRNIDSVCVASVIGITG-ARLRLRLD-------GSDNKNDF 223

  Fly   845 WFCYHEKSPCIFPAGFCSVNNISVTPPNGYDSRTFTWEGYLRD--TGAVAAGQHLFHRIIP---D 904
            |...  .|..|.|.|.|......:.||.||...|.:|..:|..  ||:..|....|....|   .
Mouse   224 WRLV--DSSDIQPVGTCEQGGDLLQPPLGYTLNTSSWPMFLLRVLTGSELAPAVFFKEEPPRPLQ 286

  Fly   905 HGFEVGMSLECADLMDPRLVCVATVARVVGRLLKVHFDGWTDEYDQWLDCESADIYPVGWCVLVN 969
            :.|.|||.:|..|..:|.::|.||:..|.|..|.:.||||:..:|.|.|.:|.||:|||||.|..
Mouse   287 NNFIVGMKIEAVDRKNPFMICPATIGAVCGDQLHITFDGWSGAFDYWCDYDSRDIFPVGWCRLTG 351

  Fly   970 HKLEGPPRVA----------------------HQQAPKPAPKPKI--------QRKRKPKKGAAG 1004
            ..|:.|.::.                      .::||:.|.:|..        .|..|..:|.|.
Mouse   352 DVLQPPGKIVEKRPRRKRRTRLWRLRTALLGNEEEAPEAAEEPGTSVLTFGDENRTLKDCRGEAA 416

  Fly  1005 GKTPTDNNTQSVKSRTIA--------------LKTTPHLPKLSIKLELKPEHHNAAFYENNQPEE 1055
            .:..|...|...::||:.              :|..        |.|.:|..|:.......:|..
Mouse   417 EEPGTSAFTFGDENRTLKDCQGGWKKPKGRGFIKPG--------KDETRPGKHDQGAPAGKKPRG 473

  Fly  1056 EG------DEEDPDAD-----------------------------GDGDGSTSHISEQSTTQSSS 1085
            .|      ||..|..|                             ||.........:..||..:.
Mouse   474 RGFTQPLEDEARPGRDVQVAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTE 538

  Fly  1086 D--LIAGSGSGSGSASLVTLATGSNKTVKKSTTKSP--------APPTVGRK 1127
            |  |.|..|.......      ...|||....|:.|        ||....||
Mouse   539 DPRLFADQGDAPAEKK------RKGKTVTTPWTEDPRLFADQGAAPAEKKRK 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT	542..647	CDD:214723
		MBT	658..753	CDD:214723
		MBT	767..871	CDD:214723	30/90 (33%)
		MBT	882..975	CDD:214723	36/97 (37%)
		TonB_N	<975..1040	CDD:292650	16/108 (15%)
		SAM_Scm-like-4MBT	1160..1226	CDD:188979
		SAM	1160..1224	CDD:197735
Scml2	XP_006528733.1	MBT	153..248	CDD:214723	30/90 (33%)
		MBT	266..357	CDD:214723	35/90 (39%)
		PTZ00121	<403..>742	CDD:173412	36/196 (18%)
		SLED	877..986	CDD:371916
		SAM_Scm	1062..1132	CDD:188977
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839866
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3766
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740