Protein Alignment Sfmbt and L3mbtl4

DIOPT Version :10

• Sequence 1: NP_001137821.1
• Gene: Sfmbt / 34709
• FlyBaseID: FBgn0032475
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: NP_001420345.1
• Gene: L3mbtl4 / 103690158
• RGDID: 1587524
• Length: 613
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 183/614 - (29%)
• Similarity: 268/614 - (43%)
• Gaps: 117/614 - (19%)

  Fly   657 WKDFLVGRLSGARTLPSNFYNKINDSL---QSRFRLGLNLECVDKDRISQVRLATVTKIVGKRLF 718
            |:.:|  |...|...|...::| :.|.   ::.|::|:.||.:|..|.|...:.:|.::.|.||.
  Rat    54 WEQYL--REGNAVAAPVELFSK-DQSFPEHENGFQVGMRLEGIDARRPSVFCVLSVAEVCGYRLR 115

  Fly   719 LRYFDSDDG------FWCHEDSPIIHPVGWATTVGHNLAAPQDYLERMLAGREAMIEVHEDDATI 777
            |.:    ||      ||.:..||.||||||.....|.|..|:||.:......:.:......:|..
  Rat   116 LHF----DGYLSCYDFWTNAGSPDIHPVGWCQKTKHELHIPRDYRKDKFVWMDYLKACRLQNAPK 176

  Fly   778 ELFKMNFTFDEYYSDGKT-NSFVEGMKLEAVDPLNLSSICPATVMAVLKFGYMMIRIDSYQPDAS 841
            :||:      ...|:|.. ..|..|||:||||..|...:|.|||..:::   ..:|:.|...|.|
  Rat   177 KLFR------NRSSNGPVPKEFQVGMKVEAVDRRNPCLMCVATVADIVE---DRVRVHSDSWDDS 232

  Fly   842 GSDWFCYHEKSPCIFPAGFCSVNNISVTPPNGYDS-RTFTWEGYLRDTGAVAAGQHLFHRIIPDH 905
             .|::| ...||||.|.|:|..|..::..|.||.. ..|:|..||:.|.|.|.....|:...| |
  Rat   233 -FDYWC-DVSSPCIQPVGWCQENGRNLVTPPGYPGPDKFSWADYLQATQAKAVPAKAFNTRAP-H 294

  Fly   906 GFEVGMSLECADLMDPRLVCVATVARVVGRLLKVHFDGWTDEYDQWLDCESADIYPVGWCVLVNH 970
            ||...:.||..|..:|||:.||||..|....:|:|||||..:||.|:|.:|.||:|:|||.:..|
  Rat   295 GFLPNLKLEAVDKRNPRLIRVATVTDVDDYRVKIHFDGWDHKYDYWMDADSQDIHPIGWCDVTGH 359

  Fly   971 KLEGP-----PRVAHQQAPKPAPKPK-IQRKRKPKKG---AAGGKTPTDNNTQSVKSRTIALKTT 1026
            .||.|     .::...|...|.|..: |...|.|:..   :|.|...:|.|.:    |..||:..
  Rat   360 PLEVPYGSEHVKILPGQPSCPTPGCRGIGHIRGPRYAGHHSAFGCPYSDVNLK----REAALQDR 420

  Fly  1027 PHLPKLSIKLELKPEHH------NAAFYENNQPEEEGDE---------------EDPDADGDGDG 1070
            .. .:....||..|.|.      |..|  |.:.||...|               ||.|.|
  Rat   421 LR-EQTQANLEFDPSHSKSENLCNLNF--NGKCEEVDSECRLVQQAKCLKIKGREDTDLD----- 477

  Fly  1071 STSHISEQSTTQSSSDLIAGSGSGSGSASLVTLATGSNKTVKKSTTKSPAPP----TVGRKATSY 1131
              :...|.|.:|....|                      ....|.|...|.|    .:||:
  Rat   478 --NLFREYSASQVQQML----------------------HQPLSMTSMSAHPFRDLPLGRE---- 514

  Fly  1132 IANSSATNNKYIPRLADIDSSEPHLELVPDTWNVYDVSQFLR-VNDCTAHCDTFSRNKIDGKRLL 1195
                  .:.|.:|.:|||.:||      ...|.|.:|::|:: :..|..|...|.:.:||||..|
  Rat   515 ------QHCKLLPGVADIQASE------VARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFL 567

  Fly  1196 QLTKDDIMPLLGMKVGPALKISDLIAQLK 1224
            .||:.||:.::.:|:||||||.:.|...:
  Rat   568 LLTQADIVKVMRIKLGPALKIYNSILMFR 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sfmbt	NP_001137821.1	MBT_dSfmbt_rpt1	564..672	CDD:439109	4/14 (29%)
		MBT_dSfmbt_rpt2	674..753	CDD:439112	28/87 (32%)
		MBT_dSfmbt_rpt3	798..904	CDD:439115	38/106 (36%)
		MBT_dSfmbt_rpt4	905..976	CDD:439118	35/75 (47%)
		SAM_Scm-like-4MBT	1160..1226	CDD:188979	24/66 (36%)
L3mbtl4	NP_001420345.1	MBT	79..179	CDD:459242	30/103 (29%)
		MBT	188..279	CDD:459242	34/95 (36%)
		MBT	288..368	CDD:459242	37/80 (46%)
		zf-C2HC	379..407	CDD:460240	7/27 (26%)
		SAM_Scm-like-3MBT3,4	531..596	CDD:188981	24/64 (38%)