Protein Alignment ADGRD2 and mthl1

DIOPT Version :9

• Sequence 1: NP_001382354.1
• Gene: ADGRD2 / 347088
• HGNCID: 18651
• Length: 982
• Species: Homo sapiens
• Sequence 2: NP_001285340.1
• Gene: mthl1 / 32637
• FlyBaseID: FBgn0030766
• Length: 676
• Species: Drosophila melanogaster
• Alignment Length: 453
• Identity: 103/453 - (22%)
• Similarity: 160/453 - (35%)
• Gaps: 143/453 - (31%)

Human   578 LEGPDLEPQAPASSEEANRVQRFLST-------------QVGSAIISSEVWDVTGEVNVAMTFHL 629
            |:..||:|...|:.:...|:...|..             |.|...|:.:..|...:.|.|| ..|
  Fly   209 LQNCDLQPNHQAAVDGLLRLSPQLPEGSYQTSYGLPDCGQPGGYSIAGDWQDAKLDRNTAM-LQL 272

Human   630 QHRAQSPLFPPHPPSPYTGGAWATTGCSVAALYLDST-------ACFCNHSTSFAILLQIYEVQR 687
            .|:                      ..|.....|:.|       ...|.|..|.|....|::...
  Fly   273 PHK----------------------NLSAGQYCLEHTQREGEVKIIACQHLFSSAAGAGIHDGSI 315

Human   688 G-----PEEESLLRTLSFVGCGVSFCALTTTFLLFLVAG--VPKSERTTVHKNLTFS-------- 737
            |     ...::|.:.:...|..||...|:.|    ||||  :|     .||..|.:.
  Fly   316 GGTIEQANGQNLQKAVLTGGILVSIVFLSAT----LVAGFLLP-----AVHHALHWRCQICYVTC 371

Human   738 -------LASAEGFLMTSEWAKANEVACVAVTVAMHFLFLVAFSWMLVEGLLLW----------- 784
                   ||..|    .|...:....||..:.:.|.|.||.||.|:......:|
  Fly   372 LLFGKILLAIEE----LSSSLQPGSAACHTLAITMQFFFLAAFFWLNTMCFNIWWTFRDFRPSSL 432

Human   785 -RKVVAVSMHPGPGMRLYHATGWGVP--VGIVAVTLAMLPH-DYVAPG----HCWLNVHTNAIWA 841
             |...|:..:      ||....||.|  :..||..:..||. ..:.||    :||.:....:|:|
  Fly   433 ERNQEALRRY------LYSLYAWGGPLLITFVAACVDQLPETTLLRPGFGQLYCWFDNRNLSIFA 491

Human   842 -FVGPVLFVLTANTCILARVVMITVSSARRRARMLSPQPCLQQQIWTQIW------------ATV 893
             |.||:..:|.||       :.:.||:.              .|:...:|            |..
  Fly   492 YFYGPIGLLLCAN-------IALFVSTT--------------HQLTCGLWKRDDVKSSSEKSALG 535

Human   894 KPVLVLLPVLGLTWLAGILVHL--SP--AWAYAAVGLNSIQGLYIFLVYAACNEEVRSALQRM 952
            :..|.|:.|:|:||:|.||..|  .|  .|.:..: :|::||::||:| ..|..:|.:|.:|:
  Fly   536 RVCLKLVVVMGVTWIADILSWLVGGPHGVWFFTDL-INALQGVFIFIV-VGCQPQVWTACRRI 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ADGRD2	NP_001382354.1	None
mthl1	NP_001285340.1	7tm_4	329..579	CDD:304433	70/290 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4193
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7362
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810