Sequence 1: | NP_477351.1 | Gene: | Sirt1 / 34708 | FlyBaseID: | FBgn0024291 | Length: | 823 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_071877.3 | Gene: | Sirt2 / 64383 | MGIID: | 1927664 | Length: | 389 | Species: | Mus musculus |
Alignment Length: | 500 | Identity: | 155/500 - (31%) |
---|---|---|---|
Similarity: | 226/500 - (45%) | Gaps: | 145/500 - (28%) |
- Green bases have known domain annotations that are detailed below.
Fly 117 EEEEEDDEEGITGTSNEDEDSSSNCSSSVEPDWKLRWLQREFYTGRVPRQVIASIMPHFATGLAG 181
Fly 182 DTDDSVLWDYLAHLLNEPKRRNKLASVNTFDDVISLV--KKSQKIIVLTGAGVSVSCGIPDFRS- 243
Fly 244 TNGIYARLA--HDFPDLPDPQAMFDINYFKRDPRPFYKFAREIYPGEFQPSPCHRFIKMLETKGK 306
Fly 307 LLRNYTQNIDTLERVAGI--QRVIECHGSFSTASC--TKCRFKCNADALRADIFAQRIPVCPQCQ 367
Fly 368 PNKEQSVDASVAVTEEELRQLVENGIMKPDIVFFGEGLPDEYHTVMATDKDVCDLLIVIGSSLKV 432
Fly 433 RPVAHIPSSIPATVPQILINREQLHH--------------LKF-------DVELLGDSDVIINQI 476
Fly 477 CHRLSDNDDCWRQLCCDESVLTESKELMPPEHSNHHLHHHLLHHRHCSSESERQSQLDTDTQSIK 541
Fly 542 SNSSADYILGSAGTCSDSGFESSTFSCGKRSTAAEAAAIERIKTD 586 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Sirt1 | NP_477351.1 | DUF592 | <202..228 | CDD:282439 | 5/27 (19%) |
SIRT1 | 222..476 | CDD:238699 | 116/281 (41%) | ||
Sirt2 | NP_071877.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..34 | 11/63 (17%) | |
Nuclear export signal. /evidence=ECO:0000250 | 41..51 | 2/9 (22%) | |||
SIRT1 | 77..331 | CDD:238699 | 118/285 (41%) | ||
Peptide inhibitor binding. /evidence=ECO:0000250 | 116..120 | 1/3 (33%) | |||
Peptide inhibitor binding. /evidence=ECO:0000250 | 232..301 | 27/68 (40%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 350..389 | 13/77 (17%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0846 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 1 | 1.000 | - | - | FOG0000643 | |
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.810 |