Protein Alignment Sirt1 and Sirt7

DIOPT Version :9

• Sequence 1: NP_477351.1
• Gene: Sirt1 / 34708
• FlyBaseID: FBgn0024291
• Length: 823
• Species: Drosophila melanogaster
• Sequence 2: XP_008766699.1
• Gene: Sirt7 / 303745
• RGDID: 1305876
• Length: 426
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 69/279 - (24%)
• Similarity: 108/279 - (38%)
• Gaps: 73/279 - (26%)

  Fly   190 DYLAHLLNEPKRRN--KLASVNTFDD----------VISLVKKSQKIIVLTGAGVSVSCGIPDFR 242
            |.:..|....:||.  |.......||          :...|:.::.::|.||||:|.:..|||:|
  Rat    57 DLVTELQGRSRRREGLKRRQEEVCDDPEELRRKVRELAGAVRSARHLVVYTGAGISTAASIPDYR 121

  Fly   243 STNGIYARLAHDFP----DLPDPQAMFDINYFKRDPRPFYKFAREIYPGEFQPSPCHRFIKMLET 303
            ..||::..|....|    ||                            .|.:|:..|..|..|.
  Rat   122 GPNGVWTLLQKGRPVSAADL----------------------------SEAEPTLTHMSITQLH- 157

  Fly   304 KGKLLRN-YTQNIDTLERVAGIQR--VIECHGSFSTASCTKCRFKCNADALRADIFAQRIP-VCP 364
            |.||::: .:||.|.|...:|:.|  :.|.||:......:..|.:...|. :..:....:| ||.
  Rat   158 KHKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVSSAQRTQGLGDK-QMSLTVPSLPQVCT 221

  Fly   365 QCQPNKEQSVDASVAVTEEELRQLVENGI-----------MKPDIVFFGE----GLPDEYHTVMA 414
            .|.||:|.     |.|.:...|..:...:           ::..||.|||    |.|..:..  |
  Rat   222 SCIPNREY-----VRVFDVTERTALHRHLTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEA--A 279

  Fly   415 TD-KDVCDLLIVIGSSLKV 432
            |: ....|.::.:||||||
  Rat   280 TEAASKADTILCLGSSLKV 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt1	NP_477351.1	DUF592	<202..228	CDD:282439	6/37 (16%)
		SIRT1	222..476	CDD:238699	61/235 (26%)
Sirt7	XP_008766699.1	SIRT7	102..339	CDD:238701	61/234 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0846
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810