DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-H and DNAJB14

DIOPT Version :9

Sequence 1:	NP_001260431.1	Gene:	DnaJ-H / 34707	FlyBaseID:	FBgn0032474	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001026893.1	Gene:	DNAJB14 / 79982	HGNCID:	25881	Length:	379	Species:	Homo sapiens

Alignment Length:	149	Identity:	56/149 - (37%)
Similarity:	75/149 - (50%)	Gaps:	31/149 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NLYDVLKVAPDATDEEIKKNYRKLAKEFHPDKN--PDAGDKFKEISFAYEVLSDPEKRRIYDRYG 67
            |.|:||.|..||.||::||.|||||.:||||||  |.|.|.||:|..||.|||:||||:.||
Human   108 NYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQYD--- 169

  Fly    68 LKGLQEGAEGFSDASEFFAQWFPFDRVSSEGRGRRNGKVVVKVELTLEE---IYVGGMKKKVEYN 129
            |.|.:|.|                  .:.:..||.|.....:.::|.|:   |:.||     .:.
Human   170 LTGNEEQA------------------CNHQNNGRFNFHRGCEADITPEDLFNIFFGG-----GFP 211

  Fly   130 RQKLCSKCNGDGGPKEAHE 148
            ...:.|..||..|..:.|:
Human   212 SGSVHSFSNGRAGYSQQHQ 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-H	NP_001260431.1	DnaJ	1..363	CDD:223560	56/149 (38%)
		DnaJ	5..64	CDD:278647	37/60 (62%)
		DnaJ_C	106..329	CDD:199909	10/46 (22%)
		DnaJ_zf	134..197	CDD:199908	5/15 (33%)
DNAJB14	NP_001026893.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	55..94
		DnaJ	107..>214	CDD:223560	51/131 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..241		4/12 (33%)
		DUF1977	271..371	CDD:370429
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910