DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-H and dnajc11

DIOPT Version :9

Sequence 1:	NP_001260431.1	Gene:	DnaJ-H / 34707	FlyBaseID:	FBgn0032474	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001072583.1	Gene:	dnajc11 / 780038	XenbaseID:	XB-GENE-942676	Length:	559	Species:	Xenopus tropicalis

Alignment Length:	337	Identity:	89/337 - (26%)
Similarity:	125/337 - (37%)	Gaps:	111/337 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDNLNLYDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPD------AGDKFKEISFAYEVLSDPEK 59
            :||.:.|.:|.|..:||.||:|.:||:|...:||||:.|      |...|..:..||||||||:.
Frog    10 VDNDDYYSLLNVRREATQEELKASYRRLCMLYHPDKHRDPELKKQAEQLFNLVHQAYEVLSDPQS 74

  Fly    60 RRIYDRYGLKGLQ----EGAEGFSDASEFFAQWFPFDRVSSEGRGRR-----NGKVVVKVELTLE 115
            |.|||.||.|||:    |..|....|:|...:   |:|:..|...||     |.|..:.|.:...
Frog    75 RAIYDIYGKKGLEMEGWEVVERKRTAAEIREE---FERLQREREERRLQQRTNPKGTISVGIDAT 136

  Fly   116 EIY----------VGGMKKKVEYNRQKL-------------------CSKCNGDGGPK-----EA 146
            |::          .|....::|.||..:                   .|..||:||..     ..
Frog   137 ELFDRYDEDFEDIPGSGFPQIEINRMHISQSIEAPLTATDTAILSGSLSTQNGNGGGSINLALRR 201

  Fly   147 HESCETCG----GAGRAAAFTFMGLSPFDTTCPTC----------DGRGFTIRD----------D 187
            ..|.:..|    |||......| ||..|....|.|          ..||  ||.          |
Frog   202 VTSAKGWGELEFGAGDLQGPLF-GLKIFRNLTPKCFFTTNCALQFSSRG--IRPGLTTMVARNLD 263

  Fly   188 KKCSPCQGSGFVEQK----------MKRD-------LVVERGAPHMLKV-----PFANEGH---- 226
            |..     .|:::.:          :.||       |..:.|.||...:     .|.:|..
Frog   264 KNT-----MGYIQWRWGIQSAMNTSIVRDTKNSHFTLAFQLGIPHSFMMVSYQHKFQDEEQTRLK 323

  Fly   227 -QMRGGEFGDLI 237
             .::.|.||.|:
Frog   324 GSIKAGFFGTLV 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-H	NP_001260431.1	DnaJ	1..363	CDD:223560	89/337 (26%)
		DnaJ	5..64	CDD:278647	28/64 (44%)
		DnaJ_C	106..329	CDD:199909	41/217 (19%)
		DnaJ_zf	134..197	CDD:199908	22/91 (24%)
dnajc11	NP_001072583.1	DnaJ	14..79	CDD:365959	28/64 (44%)
dnajc11	NP_001072583.1	DUF3395	410..549	CDD:371774
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003651
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000