DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-H and dnaja2

DIOPT Version :9

Sequence 1:	NP_001260431.1	Gene:	DnaJ-H / 34707	FlyBaseID:	FBgn0032474	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001004807.1	Gene:	dnaja2 / 448048	XenbaseID:	XB-GENE-998337	Length:	410	Species:	Xenopus tropicalis

Alignment Length:	413	Identity:	160/413 - (38%)
Similarity:	240/413 - (58%)	Gaps:	33/413 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDNL---NLYDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPDAGDKFKEISFAYEVLSDPEKRRI 62
            |.|:   .|||:|.|||.|::.::||.|||||||:||||||:||||||||||||||||:||||.:
Frog     1 MSNVADTKLYDILGVAPGASENDLKKAYRKLAKEYHPDKNPNAGDKFKEISFAYEVLSNPEKREL 65

  Fly    63 YDRYGLKGLQEGAEGFSDASEFFAQWFP---FDRVSSEGR---GRRNGK-VVVKVELTLEEIYVG 120
            |||||.:||:||:.| |...:.|:..|.   |..:..:.|   |||.|: ::..::::||::| .
Frog    66 YDRYGEQGLREGSGG-SGMDDIFSHIFGGGLFGFMGGQSRSRNGRRRGEDMMHPLKVSLEDLY-N 128

  Fly   121 GMKKKVEYNRQKLCSKCNGDGGPKEAHESCETCGGAGRAAAFTFMGLSP-----FDTTCPTCDGR 180
            |...|::.::..|||.|||.||...|.:.|..|  .||........|:|     ..:.|..|:|.
Frog   129 GKTTKLQLSKNVLCSSCNGQGGKTGAVQKCSAC--RGRGVRVMIRQLAPGMVQQMQSVCSDCNGE 191

  Fly   181 GFTIRDDKKCSPCQGSGFVEQKMKRDLVVERGAPHMLKVPFANEGHQMRGGEFGDLIVVISQMEH 245
            |..|.:..:|..|:|...|::....::.|::|..|..::.|:.|..|..|.|.||:::|:.:.||
Frog   192 GEVINEKDRCKKCEGKKVVKEVKIIEVHVDKGMKHGQRITFSGEADQAPGVEPGDIVLVLQEKEH 256

  Fly   246 PIFQRRHANLYMRDLEINITEALCGYSHCFKHLDGRNVCLRTYPGEVLQHNQIKMVRGSGMPVFN 310
            .:|||...:|:|.. .|.:.|||||:...|||||.|.:.::..||:|::...:::|||.|||.:.
Frog   257 EVFQRDGNDLHMTH-RIGLVEALCGFQFTFKHLDARQIVVKYPPGKVIEPGSVRVVRGEGMPQYR 320

  Fly   311 KATDSGDLYMKFKVKFPDNDFATAPQLAMLEDLLP--PRQPIVIPKNAEEVQMTDY--------- 364
            ...:.|||::||.|.||:|::....:|..||||||  |..| .:....|||.:.::
Frog   321 NPFEKGDLFIKFDVIFPENNWINPDKLTELEDLLPSRPEAP-AVSGETEEVDLQEFDNTRGSSGG 384

  Fly   365 -KPQPRQQEDEDGQSSHFEGVQC 386
             :.:......:|..|.|..||||
Frog   385 QRREAYNDSSDDESSHHGPGVQC 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-H	NP_001260431.1	DnaJ	1..363	CDD:223560	153/378 (40%)
		DnaJ	5..64	CDD:278647	43/58 (74%)
		DnaJ_C	106..329	CDD:199909	76/227 (33%)
		DnaJ_zf	134..197	CDD:199908	22/67 (33%)
dnaja2	NP_001004807.1	PTZ00037	4..410	CDD:240236	158/410 (39%)
		DnaJ	9..67	CDD:278647	43/57 (75%)
		DnaJ_C	113..339	CDD:199909	76/229 (33%)
		DnaJ_zf	142..208	CDD:199908	22/67 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I6870
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012379at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR43888
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020