DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DnaJ-H and CG2790

DIOPT Version :9

Sequence 1:	NP_001260431.1	Gene:	DnaJ-H / 34707	FlyBaseID:	FBgn0032474	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_611986.2	Gene:	CG2790 / 37992	FlyBaseID:	FBgn0027599	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	402	Identity:	91/402 - (22%)
Similarity:	148/402 - (36%)	Gaps:	129/402 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPD----AGDKFKEISFAYEVLSDPEKRRIYDRYG 67
            |:.|::..:|.|.:||..|||:|..:|||||||    |.::|:.|..||||||||::|..||.:.
  Fly     5 YEELELQRNANDGDIKSAYRKMALRWHPDKNPDRLAEAKERFQLIQQAYEVLSDPQERSWYDNHR 69

  Fly    68 ---LKGL-QEGAEGFSDASEFFA---------QWFPFDRVSSEGRGRRNGKVVVKVELTLEEIYV 119
               |:|. .:.||...|..:||.         ....|.||.::          |.|::..|::
  Fly    70 EQILRGKNSDYAENCLDVFQFFTSSCYKGYGDNEHGFYRVYTD----------VFVQIASEDL-- 122

  Fly   120 GGMKKKVEYNRQKLCSKCNGDG-GPKEAHESCETCGGAGRAAAF--TFMGLSPFDTTCPTCDGRG 181
                        :...|.:..| .|...|.:.......|...||  .:.....:|..||
  Fly   123 ------------EFMDKDDRLGMAPDFGHSNSSYEDVVGPFYAFWQAYSTRKTYDWLCP------ 169

  Fly   182 FTIRDDKKCSPCQGSGFVEQKMKRDLVVERGAPHMLKVPFANEGHQMRGGEFGDLIVVISQMEHP 246
            :.:|:.|:       .|:.:|::::         |.|:  .....:.|..|..:|:..:.:.:..
  Fly   170 YDVREIKE-------RFILRKVEKE---------MKKI--VQAARKERNEEVRNLVNFVRKRDPR 216

  Fly   247 IFQRRHANLYMRDLEINITEALCGYSHCFKHLDGRNVCLRTYPGEVLQHNQIKMVRGSGMPVFNK 311
            :      ..|.|.||..:.      ::..|..:.|...||.      :..::..||.:.  |||:
  Fly   217 V------QAYRRMLEERVE------ANRLKQEEKRKEQLRK------RQEELAAVRKNN--VFNE 261

  Fly   312 ATDSGDLYMKFKVKFPDNDFATAPQLAMLEDLLPPRQPIVIPKNAEEVQMTDYKPQPRQQEDE-- 374
            ..:.                    ||..||                  |..|.|.:....|||
  Fly   262 GYEE--------------------QLKQLE------------------QQYDSKSEDYTDEDEND 288

  Fly   375 -DGQSSHFEGVQ 385
             ||:....||.|
  Fly   289 DDGEDFDHEGGQ 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-H	NP_001260431.1	DnaJ	1..363	CDD:223560	81/375 (22%)
		DnaJ	5..64	CDD:278647	29/60 (48%)
		DnaJ_C	106..329	CDD:199909	35/225 (16%)
		DnaJ_zf	134..197	CDD:199908	12/65 (18%)
CG2790	NP_611986.2	DnaJ	3..66	CDD:278647	29/60 (48%)
		ZUO1	19..>252	CDD:227594	67/298 (22%)
		zf-C2H2_jaz	313..337	CDD:288983
		C2H2 Zn finger	315..337	CDD:275371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910