DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-H and dnajc11a

DIOPT Version :9

Sequence 1:	NP_001260431.1	Gene:	DnaJ-H / 34707	FlyBaseID:	FBgn0032474	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_997796.1	Gene:	dnajc11a / 322953	ZFINID:	ZDB-GENE-030131-1673	Length:	563	Species:	Danio rerio

Alignment Length:	363	Identity:	89/363 - (24%)
Similarity:	133/363 - (36%)	Gaps:	83/363 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDNLNLYDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPD------AGDKFKEISFAYEVLSDPEK 59
            :||.:.|.:|.|..:||.||:|.:||:|...:||||:.|      |...|..:..||||||||:.
Zfish    10 IDNDDYYSLLNVRREATQEELKASYRRLCMLYHPDKHRDPELKKQAEQLFNLVHQAYEVLSDPQA 74

  Fly    60 RRIYDRYGLKGLQ----EGAEGFSDASEFFAQWFPFDRVSSEGR--GRRNGKVVVKVELTLEEIY 118
            |.|||.||.|||.    |..|.....:|...::....|...|.|  .|.|.|..:.|.:...:::
Zfish    75 RAIYDIYGKKGLDVEGWEVVERKRTPAEIREEYERLQREREERRLQQRTNPKGTISVGIDATDLF 139

  Fly   119 VGGMKKKVEYNRQKLCSKCNGDGGPKEAH---------ESCETCGGAGRAAAFTFMGLSPFDTTC 174
                    :|..:.......|.||....|         :|.|        |..|....:....:.
Zfish   140 --------DYYEEDYDEISGGGGGGGLPHIEINKMHISQSIE--------APLTTSDTAVLSGSL 188

  Fly   175 PTCDGRG-----FTIRDDKKCSPCQGSGFVEQKMKRDLVVERGAPHMLKVPF-ANEGHQMRGGEF 233
            .|.:|.|     ..:|   :.:..:|.|.||                    | |.:.|   |..|
Zfish   189 STHNGNGGGNISLALR---RVTSAKGWGEVE--------------------FGAGDTH---GPLF 227

  Fly   234 GDLIVVISQMEHPIFQRRHANLYM--RDLEINITEALCGYSHCFKHLDGRNVCLRTYPGEVLQHN 296
            |  :.:...:....|...|..|..  |.:...:|..|.      :|||...:....:........
Zfish   228 G--LKIFRNLTSRCFTTAHCGLQFSSRGIRPGLTTMLA------RHLDKNTMGYLQWRWGTQSSM 284

  Fly   297 QIKMVRGSGMPVFNKATDSG----DLYMKFKVKFPDND 330
            ...:||.:....|..|...|    .:.|.::.||.|:|
Zfish   285 NTSIVRDTKSSHFTFAVQLGIPHTFIMMSYQYKFQDDD 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-H	NP_001260431.1	DnaJ	1..363	CDD:223560	89/363 (25%)
		DnaJ	5..64	CDD:278647	28/64 (44%)
		DnaJ_C	106..329	CDD:199909	41/243 (17%)
		DnaJ_zf	134..197	CDD:199908	13/76 (17%)
dnajc11a	NP_997796.1	DnaJ	14..79	CDD:278647	28/64 (44%)
dnajc11a	NP_997796.1	DUF3395	421..553	CDD:288708
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003651
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000