DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-H and AgaP_AGAP007361

DIOPT Version :9

Sequence 1:	NP_001260431.1	Gene:	DnaJ-H / 34707	FlyBaseID:	FBgn0032474	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	XP_308470.4	Gene:	AgaP_AGAP007361 / 1269820	VectorBaseID:	AGAP007361	Length:	785	Species:	Anopheles gambiae

Alignment Length:	409	Identity:	84/409 - (20%)
Similarity:	147/409 - (35%)	Gaps:	132/409 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDNLNLYDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPDAGDK--FKEISFAYEVLSDPEKRRIY 63
            |.|.:.|::|.|...::.:||||.||.|:...||||  :.||:  |.:::.||:.|:|.|.|:.:
Mosquito   101 MSNFDPYEILGVPLGSSQKEIKKAYRTLSVILHPDK--ETGDEKAFMKLTKAYQALTDDEARKNW 163

  Fly    64 DRY-----------------------------GLKGL-------------------QEGAEGFSD 80
            ::|                             ||.||                   ..|.:...|
Mosquito   164 EKYGNPDGPGATSFGIALPSWIVEKENSVWVLGLYGLVFMVALPIVVGTWWYRSIRYSGDKVLLD 228

  Fly    81 ASEFFAQWFPFDR--------------VSSEGRGRRNGKVVVKVELTLEEIYVGGMKKKVEYNRQ 131
            .:..:  |:.|.:              .|.|...|.|.:|   :|...:.:.|..:.:::.|..:
Mosquito   229 TTNMY--WYFFHKTPHMAVKRVIMILAASFEFEKRHNNQV---IERPSDNVEVPALIRELPYLNE 288

  Fly   132 KLCSKCNGDGGPKEAHESCETCGGAGRAAAFTFMGLSPFDTTCPTCDGRGFTIRDDKKCSPCQGS 196
            | |.:.     |.....|.:     .||.....:...|.:......| |...:|   ||.
Mosquito   289 K-CKEL-----PFARSYSLK-----ARAILHAHLSRIPLNPNTLEVD-RQLIVR---KCP----- 333

  Fly   197 GFVEQKMKRDLVVERGAPHMLKVPFANEGHQMRGGEFGDLIVVISQM--------EHPIFQRRHA 253
             ::.|:|...:      .|::.:.:|.:..::...|..:..:.:|.|        |||:.|..|.
Mosquito   334 -YLIQEMVSCV------SHLIMLAYARKIQRLPSIETIENCMKLSPMVIQGLRESEHPLMQLPHM 391

  Fly   254 NLYMRDLEINITEALCGYSHCFKHL--------DGRNVCLRTYPGEVLQHNQIKMVRGSGMPVFN 310
            ...:|        |.....:..::|        |.|...||:...| ..||.:|::  ..||:.
Mosquito   392 TKELR--------AQLARKYNTRNLQQLAQLKPDTRRAALRSLNDE-QYHNAVKVL--GQMPLI- 444

  Fly   311 KATDSGDLYMKFKVKFPDN 329
                  |..||.:|...:|
Mosquito   445 ------DFSMKCEVVDDEN 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-H	NP_001260431.1	DnaJ	1..363	CDD:223560	84/409 (21%)
		DnaJ	5..64	CDD:278647	23/60 (38%)
		DnaJ_C	106..329	CDD:199909	45/238 (19%)
		DnaJ_zf	134..197	CDD:199908	11/62 (18%)
AgaP_AGAP007361	XP_308470.4	DnaJ	105..164	CDD:278647	23/60 (38%)
		Sec63	211..>480	CDD:304568	54/297 (18%)
		Sec63	<639..734	CDD:304568
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910