DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-H and Dnajc14

DIOPT Version :9

Sequence 1:	NP_001260431.1	Gene:	DnaJ-H / 34707	FlyBaseID:	FBgn0032474	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_446142.2	Gene:	Dnajc14 / 114481	RGDID:	620489	Length:	703	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	62/235 - (26%)
Similarity:	94/235 - (40%)	Gaps:	72/235 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DNLNLYDVLKVAPDATDEEIKKNYRKLAKEFHPDKN--PDAGDKFKEISFAYEVLSDPEKRRIYD 64
            |.||.:.||.|...|:|.|:||.||:||...|||||  |.|.:.||.:..|::::|:||:|:.|:
  Rat   441 DELNPFHVLGVEATASDIELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNPERRKEYE 505

  Fly    65 RYGLKGLQEGAEGFSDASEFFAQWFPFDRVSSEGRGRRNGKVVVKVELTLEEIYVGGMKKKVEYN 129
               :|.:.|. |.....:||.:                      |::..|:|..
  Rat   506 ---MKRMAEN-ELSRSVNEFLS----------------------KLQDDLKEAM----------- 533

  Fly   130 RQKLCSKCNG-------DGGPKEAHESCETCGGAGRA------AAFTFMGLSPFDTTCPTCDGRG 181
            ...:||:|.|       |..||.| ..|..|.....|      |..:.:||.  .|.....||:
  Rat   534 NTMMCSRCQGKHRRFEMDREPKSA-RYCAECNRLHPAEEGDFWAESSMLGLK--ITYFALMDGK- 594

  Fly   182 FTIRDDKKCSPCQGSGFVEQKMKRDLVVERGAPHMLKVPF 221
              :.|..:.:.||..|.              :|...:||:
  Rat   595 --VYDITEWAGCQRVGI--------------SPDTHRVPY 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-H	NP_001260431.1	DnaJ	1..363	CDD:223560	62/235 (26%)
		DnaJ	5..64	CDD:278647	27/60 (45%)
		DnaJ_C	106..329	CDD:199909	27/129 (21%)
		DnaJ_zf	134..197	CDD:199908	20/75 (27%)
Dnajc14	NP_446142.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..150
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	164..229
		DnaJ	444..505	CDD:278647	27/60 (45%)
		Jiv90	535..621	CDD:291562	24/104 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	622..643
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	659..703
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910