DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kmg and Zfp513

DIOPT Version :9

Sequence 1:	NP_609604.1	Gene:	kmg / 34706	FlyBaseID:	FBgn0032473	Length:	747	Species:	Drosophila melanogaster
Sequence 2:	NP_001012110.1	Gene:	Zfp513 / 313913	RGDID:	1310456	Length:	541	Species:	Rattus norvegicus

Alignment Length:	360	Identity:	69/360 - (19%)
Similarity:	109/360 - (30%)	Gaps:	124/360 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 FQCQKCSYSTPIRARFKKHVKYHS--MPLIKCSSCDFHTPYKWNLDRHTKNHGANGHFKCSCCDF 383
            :.|:.|::.:...:..|:|::.||  .| .:|..|.:.:....||.|||:.|.....::|..|.|
  Rat   150 YSCRLCAFVSHYSSHLKRHMQTHSGEKP-FRCGRCPYASAQLVNLTRHTRTHTGEKPYRCPHCPF 213

  Fly   384 STDIKQSLTIHESNH---------------------HVPMPVHQMG---NRSRD----------- 413
            :.....:|..|:..|                     ..|.|..|.|   .||.|
  Rat   214 ACSSLGNLRRHQRTHTGPPTPPCPTCGFRCCAPRPTRPPSPTEQEGTMPRRSEDALILPDLSLHV 278

  Fly   414 ----------------EAEDLVD----------------------QQSSGSRKPETF-------K 433
                            |.|.|..                      ::..|||.....       :
  Rat   279 PPGGTSFLPDCGQLRGEGEGLCGTGSEPLPELLFPWTCRGCGQELEEGEGSRLGTAMCGRCMRGE 343

  Fly   434 NGGATVASTESLLPRTSGIVCSHCQKRVGNAMQLINHLQV--------CTLALHNTTQLQASINA 490
            :||......:.  |...|..||.|.........|..|::.        |....:.:..|. ::..
  Rat   344 SGGGGSGGPQG--PSDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHLD-NLKR 405

  Fly   491 EVDLHDEDFP-NAPTDLSYCGVETAPGYGEVTEVLPEEPEDLAPLK---------KVFKCPHCSF 545
            ...:|..:.| ..|.....||                   :||.||         |.|:|..|::
  Rat   406 HQRVHTGEKPYKCPLCPYACG-------------------NLANLKRHGRIHSGDKPFRCSLCNY 451

  Fly   546 WAATASRFHVHIVGHLNRKPFECSLCAYRSNWRWD 580
            ....:.....|::.|...|||.|:.|||.:. .||
  Rat   452 SCNQSMNLKRHMLRHTGEKPFRCATCAYTTG-HWD 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kmg	NP_609604.1	C2H2 Zn finger	540..560	CDD:275370	3/19 (16%)
kmg	NP_609604.1	C2H2 Zn finger	568..586	CDD:275370	6/13 (46%)
Zfp513	NP_001012110.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..120
		C2H2 Zn finger	152..172	CDD:275368	4/19 (21%)
		zf-H2C2_2	164..189	CDD:290200	7/25 (28%)
		COG5048	176..>228	CDD:227381	14/52 (27%)
		C2H2 Zn finger	180..200	CDD:275368	7/19 (37%)
		zf-H2C2_2	192..217	CDD:290200	9/24 (38%)
		C2H2 Zn finger	208..228	CDD:275368	5/19 (26%)
		C2H2 Zn finger	362..382	CDD:275368	5/19 (26%)
		COG5048	<372..>450	CDD:227381	16/97 (16%)
		zf-H2C2_2	374..399	CDD:290200	3/24 (13%)
		C2H2 Zn finger	390..410	CDD:275368	2/20 (10%)
		zf-H2C2_2	402..425	CDD:290200	3/22 (14%)
		COG5048	414..>487	CDD:227381	23/92 (25%)
		C2H2 Zn finger	418..438	CDD:275368	7/38 (18%)
		C2H2 Zn finger	446..466	CDD:275368	3/19 (16%)
		zf-H2C2_2	458..481	CDD:290200	9/22 (41%)
		C2H2 Zn finger	474..493	CDD:275368	6/13 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	492..541
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24403
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100