Protein Alignment kmg and Zfp407

DIOPT Version :10

• Sequence 1: NP_609604.1
• Gene: kmg / 34706
• FlyBaseID: FBgn0032473
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: XP_008770443.2
• Gene: Zfp407 / 307213
• RGDID: 1310645
• Length: 2255
• Species: Rattus norvegicus
• Alignment Length: 925
• Identity: 186/925 - (20%)
• Similarity: 287/925 - (31%)
• Gaps: 334/925 - (36%)

  Fly    13 RLVVRSLVSGAPLYQSSIEGGAGAVL---PMSQSVQPLIGQDFLEQQLEQYKANNFMFPLSMAGF 74
            ||.|:.|       ::.::..|..||   .|.:.||.|........::.|.|..:     .::||
  Rat   450 RLYVKHL-------RTQMKANAQPVLEQMQMGKDVQSLCVTTSDNPEVMQDKTAS-----GLSGF 502

  Fly    75 VSADSAPPGDLAKENMENSLPDGNPCNN------NNDD---ELPQCKIRR-NYSCNQCAFFTQNP 129
            ...     |.|..:..::.|....||..      |..|   .:.:|.:|. .:.|..|.|.:.:.
  Rat   503 TRL-----GSLEVKPADHQLSVQCPCTECGQITANKTDLDIHVQKCHVREVQFHCQTCDFSSPSR 562

  Fly   130 RSHLSHLR-DVHGERIVINECKLCLYASRHFQKLVRHMKMVHG----CSDDGGAVQGSGAQPRGK 189
            |....||. :.|.:...:..|:.|.:.|.....|..|||..||    |:               .
  Rat   563 RDLEEHLHSNQHQQTTPVLSCQCCPFISLSETSLRVHMKEKHGMGFFCT---------------S 612

  Fly   190 RNLSREVRKRRLEESIEGQGATGQCLDLSVLRMIQNGPPLEQLKVELQQQEMQLLASVQAYNRQQ 254
            .||...      |..:|...||
  Rat   613 CNLFLS------ERDVEEHRAT------------------------------------------- 628

  Fly   255 EMLQLQQIVESHDNIFSMAYEFQTKLMPPKQAESLK---------LEQQNSSSDSEETAKS---- 306
                     |:|:::          ::.||.|.||.         ||..|.:...|::.|:
  Rat   629 ---------EAHNSL----------VVQPKTASSLSRDSVLPLSTLESDNMADSREDSGKASQEE 674

  Fly   307 -----PSPDTRELVSGKEQFQCQKCSYSTPIRARFKKHVK------YHSMPLIKCSSCDFHTPYK 360
                 .|..|....|.|.||||:||.|.|.......:|:|      ||.:    |.:|:.::..|
  Rat   675 PAESRASHGTEARHSSKPQFQCKKCFYKTRSSTVLTRHIKLRHGQDYHFL----CKACNLYSLSK 735

  Fly   361 WNLDRH----------TKNHGANGHFKC--SCCDFSTDIKQSLTIHESNH---HV---------- 400
            ..:::|          .||:......:|  ..|..:.|.|:...:..|..   |:
  Rat   736 EGMEKHIKRSKHLENAKKNNIGLSFEECIERVCIGANDKKEESNVSGSGRPEGHIGVRLQEHSHC 800

  Fly   401 ------PMPVHQMGNRSRDEAEDLVDQQSSGSRK---PETFKNGGATVASTESLLPR-------- 448
                  |..:.|.|..::::...|......|..|   ..|..:.|...:|..:|...
  Rat   801 EQSMLTPKELPQSGVITKEDELGLASTPKRGRPKGSISRTCSHCGLLASSITNLTVHIRRKHSHQ 865

  Fly   449 -------------TSGIVCSHC--QKRVG---------NAMQLI-----NHLQVC---TLALHNT 481
                         |.|.:..||  :|..|         ::..:|     .:|:.|   |||| ..
  Rat   866 YSYLCKVCKYYTVTKGDMERHCATKKHKGRVEIEANGKHSSDIIVGPEGGNLEACKKSTLAL-TV 929

  Fly   482 TQLQASINAEVDLHDEDFP---NAPTDLSYCGVETAPGYGEVTEVLPE-------EPEDLAPLKK 536
            :..||:.:|:.|....|.|   |..|..:..|.......|||:..|.:       |.|||.....
  Rat   930 SDEQANKSAKSDASTLDKPVVGNGDTGDADAGSALQSVDGEVSSQLADKKGQIALETEDLQQHDD 994

  Fly   537 VF-----------KCPHCSFWAATASRFHVHIV-GHLNRKPFECSLCAYRSNWRWDITKHIRLKA 589
            ..           ||.||.|.|.:|:...:|:. .|.....|.|..|.|.:..|.::|:|...:
  Rat   995 ACSQRDVAGSSDNKCLHCEFSAHSAASLELHVKRKHTKEFEFYCMACDYYAVTRREMTRHAATE- 1058

  Fly   590 LRDRSHNQAQVLMNDETGRRNYAKYNQYLTMMKVSAEQLADSKGMRTGEMIVMPPEKLDDHHPME 654
                               ::..|...||:...|.|.....||.      |.:|.|:    |...
  Rat  1059 -------------------KHKMKRQSYLSSSNVEAGSSEISKS------ITIPEEE----HSQN 1094

  Fly   655 TEEIIEMVDSAHSTSALDLRKPRD----------DQTEDLAG--------------NSDE----- 690
            :||.  .:....|:..|..|.|.|          |.::.|..              |.|.
  Rat  1095 SEEF--QISPHQSSGTLQSRHPADCSILYDNTNLDMSKVLCAPDSVAVVAEQESNFNEDHSFCET 1157

  Fly   691 LPQEGAKTEPNLEPLSFKSLNSSQVMPKPKGSP---------------------MNLTKTDGGQS 734
            |.|..|| :.:::|....|||:    |..:.||                     .||....|..|
  Rat  1158 LHQPLAK-DRSIKPREIVSLNT----PSNRSSPGCLQSGNLASSAVDSETAKRNHNLLDDVGDTS 1217

  Fly   735 ----DETTSADESNE 745
                ||..|.|.|.|
  Rat  1218 AHCEDEGGSLDGSEE 1232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kmg	NP_609604.1	C2H2 Zn finger	540..560	CDD:275370	7/20 (35%)
		C2H2 Zn finger	568..586	CDD:275370	6/17 (35%)
Zfp407	XP_008770443.2	C2H2 Zn finger	523..544	CDD:275368	3/20 (15%)
		C2H2 Zn finger	552..574	CDD:275368	6/21 (29%)
		C2H2 Zn finger	583..601	CDD:275368	5/17 (29%)
		C2H2 Zn finger	1405..1434	CDD:275371
		C2H2 Zn finger	1435..1457	CDD:275371
		C2H2 Zn finger	1477..1498	CDD:275371
		C2H2 Zn finger	1528..1550	CDD:275368
		zf-H2C2_2	1546..1567	CDD:463886
		C2H2 Zn finger	1558..1578	CDD:275368
		C2H2 Zn finger	1586..1606	CDD:275368
		C2H2 Zn finger	1619..1639	CDD:275368
		zf-H2C2_2	1631..1658	CDD:463886
		C2H2 Zn finger	1647..1669	CDD:275368
		C2H2 Zn finger	1677..1697	CDD:275368
		zf-H2C2_2	1689..1714	CDD:463886
		zf-H2C2_5	1703..1727	CDD:404746
		C2H2 Zn finger	1705..1725	CDD:275368
		zf-H2C2_2	1717..1742	CDD:463886
		C2H2 Zn finger	1733..1750	CDD:275368