DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Pk34A and GSK1

DIOPT Version :9

Sequence 1:NP_609603.1 Gene:Pk34A / 34705 FlyBaseID:FBgn0028410 Length:392 Species:Drosophila melanogaster
Sequence 2:NP_172127.1 Gene:GSK1 / 837150 AraportID:AT1G06390 Length:407 Species:Arabidopsis thaliana


Alignment Length:357 Identity:139/357 - (38%)
Similarity:202/357 - (56%) Gaps:18/357 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 VISTYAVGRLCSEPALVRIEVKDLIGSGSFGRVYQAHVNESEEIVAVKQTLYNPKLSQGEAEIMG 90
            :|||...|:.......:....:.::|:||||.|:||...|:.|.||:|:.|.:.:....|.::|.
plant    52 IISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGESVAIKKVLQDRRYKNRELQLMR 116

  Fly    91 QLKDHNNIVRLIMHSSVSLGFPSVDYVLLVMEYMPMTLLDYINYHLTVLQPAERLINVRILSYQM 155
            .: ||.|::.| .|...|.......::.|||||:|.||...:. |.|.......:..|::.:||:
plant   117 PM-DHPNVISL-KHCFFSTTSRDELFLNLVMEYVPETLYRVLR-HYTSSNQRMPIFYVKLYTYQI 178

  Fly   156 FRGLGYLHLL-GISHRDVKPENLLIDNQKMVLKLSDFGSAKLLVPQEPSISYICSRLYRAPELFA 219
            ||||.|:|.: |:.||||||:|||:|.....:||.||||||:||..||:|||||||.||||||..
plant   179 FRGLAYIHTVPGVCHRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIF 243

  Fly   220 GYELYSCAVDIWSAGCVLAELLKGYPLFSSHKHDRKQLRLIVNMLGTDGLERAPEILSKCGNSLH 284
            |...|:.::|||||||||||||.|.|||.. ::...||..|:.:|||...|   ||  :|.|..:
plant   244 GATEYTASIDIWSAGCVLAELLLGQPLFPG-ENSVDQLVEIIKVLGTPTRE---EI--RCMNPNY 302

  Fly   285 -----PRTTRPSWNYLLNTAVPQDLCGLLNSCFIYEAAARISPMMACSHGSYDELRIMDAMALPM 344
                 |:.....|:.:.:..:|.:...|.:....|..:.|.:.:.||:|..::|||..:|.   :
plant   303 TDFRFPQIKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFNELREPNAR---L 364

  Fly   345 PNGNPLPPLFDFNSLEMGTDPKLWVNLLPIHL 376
            |||.||||||:|.....|...:|...|:|.|:
plant   365 PNGRPLPPLFNFKQELGGASMELINRLIPEHV 396

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pk34ANP_609603.1 STKc_GSK3 39..334 CDD:271039 116/300 (39%)
S_TKc 45..328 CDD:214567 115/288 (40%)
GSK1NP_172127.1 STKc_GSK3 65..357 CDD:271039 116/300 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0658
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D990896at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
54.780

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