Protein Alignment Pk34A and Cdk8

DIOPT Version :10

• Sequence 1: NP_609603.1
• Gene: Pk34A / 34705
• FlyBaseID: FBgn0028410
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_536735.2
• Gene: Cdk8 / 39157
• FlyBaseID: FBgn0015618
• Length: 454
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 82/273 - (30%)
• Similarity: 134/273 - (49%)
• Gaps: 51/273 - (18%)

  Fly    43 RIEVKDL-------IGSGSFGRVYQAHVNESEE--IVAVKQTLYNPKLSQG---EAEIMGQLKDH 95
            |.:|:||       :|.|::|.||:|...|:.:  ..|:|| :....||..   |..::.:|| |
  Fly    13 RTKVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQ-IDGTGLSMSACREIALLRELK-H 75

  Fly    96 NNIVRLI----MHSSVSLGFPSVDYVLLVMEYMPMTLLDYINYHLTVLQPAERLI----NVRILS 152
            .|::.||    .|:...        |.|:::|....|...|.:|.......::::    .|:.|.
  Fly    76 QNVITLIRVFLSHNDRK--------VFLLIDYAEHDLWHIIKFHRAAKATKKQVVVPRGMVKSLL 132

  Fly   153 YQMFRGLGYLHLLGISHRDVKPENLLI---DNQKMVLKLSDFGSAKLL-VPQEPSIS---YICSR 210
            ||:..|:.|||...:.|||:||.|:|:   .|::..:|::|.|.|:|. .|.:|...   .:.:.
  Fly   133 YQILDGIHYLHSNWVLHRDLKPANILVMGDGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTF 197

  Fly   211 LYRAPELFAGYELYSCAVDIWSAGCVLAELLKGYPLFSSHKHDRK--------QLRLIVNMLG-- 265
            .||||||..|...|:.|:|||:.||:.||||...|:|...:.|.|        ||..|.|::|
  Fly   198 WYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFP 262

  Fly   266 ----TDGLERAPE 274
                .:.:::.||
  Fly   263 QDKDWEDIKKMPE 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pk34A	NP_609603.1	STKc_GSK3	39..334	CDD:271039	82/273 (30%)
Cdk8	NP_536735.2	STKc_CDK8_like	19..335	CDD:270834	79/267 (30%)