Protein Alignment Pk34A and CDK3

DIOPT Version :10

• Sequence 1: NP_609603.1
• Gene: Pk34A / 34705
• FlyBaseID: FBgn0028410
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_001249.1
• Gene: CDK3 / 1018
• HGNCID: 1772
• Length: 305
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 93/296 - (31%)
• Similarity: 144/296 - (48%)
• Gaps: 39/296 - (13%)

  Fly    50 IGSGSFGRVYQAHVNESEEIVAVKQTLYN------PKLSQGEAEIMGQLKDHNNIVRL--IMHSS 106
            ||.|::|.||:|...|:.::||:|:...:      |..:..|..::.:|| |.|||||  ::|:.
Human    10 IGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK-HPNIVRLLDVVHNE 73

  Fly   107 VSLGFPSVDYVLLVMEYMPMTLLDYINYHLTVLQPAERLINVRILSY--QMFRGLGYLHLLGISH 169
            ..|        .||.|::...|..|::     ..|...|....|.||  |:.:|:.:.|...:.|
Human    74 RKL--------YLVFEFLSQDLKKYMD-----STPGSELPLHLIKSYLFQLLQGVSFCHSHRVIH 125

  Fly   170 RDVKPENLLIDNQKMVLKLSDFGSAKLL-VPQEPSISYICSRLYRAPELFAGYELYSCAVDIWSA 233
            ||:||:|||| |:...:||:|||.|:.. ||.......:.:..|||||:..|.:.|:.||||||.
Human   126 RDLKPQNLLI-NELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSI 189

  Fly   234 GCVLAELLKGYPLFSSHKHDRKQLRLIVNMLGT------DGLERAPEILSKCGNSLHPRTTRPSW 292
            ||:.||::....||.... :..||..|..||||      .|:.:.|:.     ....|:.||...
Human   190 GCIFAEMVTRKALFPGDS-EIDQLFRIFRMLGTPSEDTWPGVTQLPDY-----KGSFPKWTRKGL 248

  Fly   293 NYLLNTAVPQDLCGLLNSCFIYEAAARISPMMACSH 328
            ..::....|:.. .||.....|:.:.||:...|.:|
Human   249 EEIVPNLEPEGR-DLLMQLLQYDPSQRITAKTALAH 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pk34A	NP_609603.1	STKc_GSK3	39..334	CDD:271039	93/296 (31%)
CDK3	NP_001249.1	STKc_CDK2_3	3..286	CDD:270844	93/296 (31%)