DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5122 and zgc:154046

DIOPT Version :9

Sequence 1:	NP_609601.1	Gene:	CG5122 / 34703	FlyBaseID:	FBgn0032471	Length:	1263	Species:	Drosophila melanogaster
Sequence 2:	NP_001073466.1	Gene:	zgc:154046 / 562075	ZFINID:	ZDB-GENE-061103-289	Length:	630	Species:	Danio rerio

Alignment Length:	599	Identity:	224/599 - (37%)
Similarity:	337/599 - (56%)	Gaps:	35/599 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   665 LKKFPALPLKQSIASYLSSIEPFLNEEELKVEQKVAKKFVD--NEGAKLQQLLEEEAEGTDNWLT 727
            |.|.|..||||:.:.||:.:||.::|||:....|:..:|:.  ..|.:||:.||..|..|:|||:
Zfish    40 LPKLPVPPLKQTCSRYLALLEPLISEEEMAHTCKLMDEFLQPGGVGERLQKSLERRARKTENWLS 104

  Fly   728 PRWTRSAYLTYQAPLTVFSSPGLSFPIQEFKDTNDFLNFTAKAIYGMCEFKQLVDQNKIPVVQMG 792
            ..|.:||||..:.|:.|:||||:..|...|:|....:.|.||.|.|:.:||:|:|...:||..:|
Zfish   105 DWWMQSAYLDSRMPVVVYSSPGVVLPKMHFQDRQGQMRFAAKLIAGVLDFKKLIDSKTLPVEYLG 169

  Fly   793 KHQLDNSQFGKIFGTVRKPGRFCDTIEQY----NDADYIVVVYNNNYFKLPIYSQSGALLHAHTL 853
            ...|...|:.::..:.|.||...|::..|    ..:.:|.||:|..:|.|.:|:..|:.|....:
Zfish   170 GKPLCMDQYYQVLSSCRIPGPKRDSVVNYATGKTPSTHITVVHNFQFFVLDVYNSDGSPLTVDQI 234

  Fly   854 RDALQDILECPIKVGKH-FGLLTHDNRSNWAEAYTVLCRPHGNADTVETIEQSLFVVCLDNCVPT 917
            ...|:.|....::..|. .|:||.::|:.|.:||..|.:...|.::|..|::|:|.|.||  .|.
Zfish   235 YVQLEKIWNTSLQTNKEPVGILTSNHRNTWGKAYNNLIKDKTNKESVRAIQKSIFTVSLD--APM 297

  Fly   918 PKGEERIVQ---AHQLLHGGGVRQNSANRWMDKTIQLIVNPNGLAGFCYEHSPADCQPLAMLMDF 979
            |:..:.:..   |.|:|||||.|.||.|||.|||:|.||..:|..|..|||:||:..|:..|:|.
Zfish   298 PRVSDEMYHNKVAAQMLHGGGSRWNSGNRWFDKTLQFIVGEDGSCGLTYEHAPAEGPPIVFLVDH 362

  Fly   980 V--QLKVTEPNYGCEGCEADKKVTSNL--------LKFQPVNECINLWLCQARRNIQRIVSQLQM 1034
            |  .:|.||            .|.:.:        |:|....| |...:.:|::|:..:|..|.:
Zfish   363 VVDYMKRTE------------MVRTPMIPLPMPLKLRFNITPE-IKKDIEKAKQNMNIMVHDLDV 414

  Fly  1035 NVINFECYGKCFIKAQGLNPDSYIQMALSLAYYSMYGKIPAQYESAHLRIFHEGRTETIRSTSNE 1099
            .|:||..||:.|.|:..|:||::|||||.||||.||......||||.||:|..||||.||||:.|
Zfish   415 RVLNFSQYGRKFPKSHKLSPDAFIQMALQLAYYRMYETCCPSYESASLRMFKLGRTEAIRSTTTE 479

  Fly  1100 SKTFLLAMQSEKASMSEKLAALQKAVDAHEKLIKEAINGQGIDRHLFGLQEMALEKGMPIPEFFR 1164
            |..|..||.....:..||.|.|:.|:..|.:|...||:||.||||:.||:.:|:|....:||.|.
Zfish   480 SLQFTKAMDDPSKNNIEKAALLKNAIKVHRELTYMAIHGQAIDRHMLGLKMVAIEDLTSLPEIFM 544

  Fly  1165 SKGYVRSVTFQLFTSQVATSNEGFMAYGPLLSDGYGVCYNPKESKITFAISAWKSCKEINTIRFA 1229
            ...:..:..|.|:||||.:..:..|.:||::.|||||||||.:..|.||::|:.||:|.|..:.:
Zfish   545 DTSFAVASHFNLYTSQVGSKTDCVMCFGPMVPDGYGVCYNPMDDHINFAVTAFNSCEETNATKLS 609

  Fly  1230 KAIKKSLNDMRKLI 1243
            ..:..:|.||:.|:
Zfish   610 TFLTDALLDMKNLL 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5122	NP_609601.1	Carn_acyltransf	665..1240	CDD:279140	222/594 (37%)
zgc:154046	NP_001073466.1	Carn_acyltransf	40..620	CDD:279140	222/594 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594975
Domainoid	1	1.000	403	1.000	Domainoid score	I686
eggNOG	1	0.900	-	-		E1_KOG3717
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm24513
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	O	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.710