DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5122 and crot

DIOPT Version :9

Sequence 1:	NP_609601.1	Gene:	CG5122 / 34703	FlyBaseID:	FBgn0032471	Length:	1263	Species:	Drosophila melanogaster
Sequence 2:	NP_001018161.1	Gene:	crot / 553204	ZFINID:	ZDB-GENE-050522-35	Length:	612	Species:	Danio rerio

Alignment Length:	608	Identity:	183/608 - (30%)
Similarity:	282/608 - (46%)	Gaps:	56/608 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   666 KKFPALP---LKQSIASYLSSIEPFLNEEELKVEQKVAKKFVDNEGAKLQQLLEEEAEGTDNWLT 727
            :..|.||   |:.:::.||.:::||.:|||......:.|:|.:..|.:|.|.|.:.|:...|||.
Zfish    18 RSLPPLPVPALRDTLSKYLDAVKPFASEEEFGATVAIVKRFEEGIGQELHQKLLQRAKSKRNWLE 82

  Fly   728 PRWTRSAYLTYQAP--LTV-FSSPGL----SFPIQEFKDTNDFLNFTAKAIYGMCEFKQLVDQNK 785
            ..|..:|||..:.|  |.| |..|..    .:|.||    ...|..|:..::...:...|:...:
Zfish    83 EWWLDTAYLEVRIPSQLNVNFGGPTAYLEHCWPPQE----GTQLERTSMVLWLTFQCWDLIRTER 143

  Fly   786 IPVVQMGKHQLDNSQFGKIFGTVRKPGRFCDTIEQYNDAD-------YIVVVYNNNYFKLPIYSQ 843
            :.:.:.|....|..||..:|.|.:.||...|||..:...:       :::|:.....|.......
Zfish   144 LAIHKAGTIPFDMDQFRMLFCTCKVPGITKDTILNFFKTESEGPCPSHVIVMCRGRIFTFDALCD 208

  Fly   844 SGALLHAHTLRDALQDILEC----PIKVGKHFGLLTHDNRSNWAEA--YTVLCRPHGNADTVETI 902
            ...|.....||. |..|..|    |  .|.....||.:.|:.||:|  |.:...| .|...:|||
Zfish   209 GRILTPPELLRQ-LTYIKNCCDGEP--EGDGVSALTTEERTRWAKAREYLISMDP-VNKTILETI 269

  Fly   903 EQSLFVVCLDNCVP--TPKGEERIVQAHQLLHGGGVRQNSANRWMDKTIQLIVNPNGLAGFCYEH 965
            :.:||||.||:..|  ||   :...|...|...|    :..|||.||:..|:...||:.....:|
Zfish   270 QSALFVVGLDDAKPYATP---DNYTQLTDLALTG----DPTNRWGDKSYNLVCYSNGIFSSNCDH 327

  Fly   966 SPADCQPLAMLMDFVQLKVTEPNYGCEGCEADKKVTSNL-----LKFQPVNECINLWLCQARRNI 1025
            :|.|...|.....:|..|:.    .|.|.....:|...:     |.| .|:|.:...:..|:...
Zfish   328 APYDAMVLVSNGYYVDQKLK----ACGGVWKGLEVVRQMPVPEELIF-TVDERVRRDIALAKEQY 387

  Fly  1026 QRIVSQLQMNVINFECYGKCFIKAQGLNPDSYIQMALSLAYYSMYGKIPAQYESAHLRIFHEGRT 1090
            .:....||:....|..:||..||.:.|:||:::|:||.||||..:|:....||:|..|.|..|||
Zfish   388 SKSCQDLQVVSYAFTSFGKTAIKKRKLHPDTFVQLALQLAYYRQHGQPGCCYETATTRRFFHGRT 452

  Fly  1091 ETIRSTSNESKTFLLAMQSEKASMSEKLAALQKAVDAHEKLIKEAINGQGIDRHLFGLQEMALEK 1155
            ||:|..:.|::.:...|.:..|:..||...|..||:.|.||:.||.:|:||||||.||..:|.|.
Zfish   453 ETMRPCTMEAQHWCRTMMNPAATTEEKRHTLHAAVNKHNKLMAEAQDGKGIDRHLLGLYLIAKEN 517

  Fly  1156 GMPIPEFFRSKGYVRS---VTFQLFTSQVA-TSNEGFMAYGPLLSDGYGVCYNPKESKITFAISA 1216
            .:|:||.:....|.:|   ..|.|.||.|. |:..|  |..|::..|||..|..::.:|..:.:|
Zfish   518 SIPVPELYADPLYTKSGGGGNFVLSTSLVGYTTVLG--AVAPMVPHGYGFFYRIRDDRIVASCTA 580

  Fly  1217 WKSCKEINTIRFAKAIKKSLNDM 1239
            |||..|.:.....:.:..||::|
Zfish   581 WKSNPETDAETLFQNLATSLHEM 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5122	NP_609601.1	Carn_acyltransf	665..1240	CDD:279140	183/608 (30%)
crot	NP_001018161.1	Carn_acyltransf	20..604	CDD:279140	183/606 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920