Protein Alignment CG5122 and CROT

DIOPT Version :9

• Sequence 1: NP_609601.1
• Gene: CG5122 / 34703
• FlyBaseID: FBgn0032471
• Length: 1263
• Species: Drosophila melanogaster
• Sequence 2: NP_001137407.1
• Gene: CROT / 54677
• HGNCID: 2366
• Length: 640
• Species: Homo sapiens
• Alignment Length: 664
• Identity: 191/664 - (28%)
• Similarity: 302/664 - (45%)
• Gaps: 108/664 - (16%)

  Fly   657 NDPNKKPELKKF------PALP---LKQSIASYLSS----------------------------I 684
            |...|..|.:.|      |:||   |::|:..||.|                            :
Human     3 NQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVTRTCYQIRGLDPDAKRGFLDLTREGIQV 67

  Fly   685 EPFLNEEELKVEQKVAKKFVDNEGAKLQQLLEEEAEGTDNWLTPRWTRSAYLTYQAP--LTV-FS 746
            :||.|:||.|..:::.:||....|.||.|.|.|.|:|..|||...|...|||..:.|  |.| |:
Human    68 KPFANQEEYKKTEEIVQKFQSGIGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFA 132

  Fly   747 SPGLSF----PIQEFKDTNDFLNFTAKAIYGMCEFKQLVDQNKIPVVQMGKHQLDNSQFGKIFGT 807
            .|...|    |.:|    ...|...:..::....:.||:.:.|:||.::|...||.:||..:|.|
Human   133 GPAAHFEHYWPPKE----GTQLERGSITLWHNLNYWQLLRKEKVPVHKVGNTPLDMNQFRMLFST 193

  Fly   808 VRKPGRFCDTIEQY-------NDADYIVVVYNNNYFKLPIYSQSGALLHAHTLRDALQDILECPI 865
            .:.||...|:|..|       ...::|||:.....|...:..:...:.....||.......:|..
Human   194 CKVPGITRDSIMNYFRTESEGRSPNHIVVLCRGRAFVFDVIHEGCLVTPPELLRQLTYIHKKCHS 258

  Fly   866 KV-GKHFGLLTHDNRSNWAEA--YTVLCRPHGNADTVETIEQSLFVVCLDNCVP--TPKGEERIV 925
            :. |.....||.:.|:.||:|  |.:...|. |...:|.|:.||.|..:::..|  ||:....|:
Human   259 EPDGPGIAALTSEERTRWAKAREYLIGLDPE-NLALLEKIQSSLLVYSMEDSSPHVTPEDYSEII 322

  Fly   926 QAHQLLHGGGVRQNSANRWMDKTIQLIVNPNGLAGFCYEHSPADCQPLAMLMDFVQLKVTEPNYG 990
            .|  :|.|     :...||.||:..||...||:.|...:|:|.|...:..:..:|..|:.:....
Human   323 AA--ILIG-----DPTVRWGDKSYNLISFSNGVFGCNCDHAPFDAMIMVNISYYVDEKIFQNEGR 380

  Fly   991 CEGCE--------------ADKKVTSNLLKFQPVNECINLWLCQARRNIQRIVSQLQMNVINFEC 1041
            .:|.|              .|:||.::          ||    ||:....|..|.||:....|..
Human   381 WKGSEKVRDIPLPEELIFIVDEKVLND----------IN----QAKAQYLREASDLQIAAYAFTS 431

  Fly  1042 YGKCFIKAQGLNPDSYIQMALSLAYYSMYGKIPAQYESAHLRIFHEGRTETIRSTSNESKTFLLA 1106
            :||...|.:.|:||::||:||.||||.::|.....||:|..|.|:.|||||:||.:.|:..:..:
Human   432 FGKKLTKNKMLHPDTFIQLALQLAYYRLHGHPGCCYETAMTRHFYHGRTETMRSCTVEAVRWCQS 496

  Fly  1107 MQSEKASMSEKLAALQKAVDAHEKLIKEAINGQGIDRHLFGLQEMALEKGMPIPEFFRSKGYVRS 1171
            ||....::.|:...:.:|...|.|::|:...|:|.||||.||..:|.|:|:|:||.|....:.:|
Human   497 MQDPSVNLRERQQKMLQAFAKHNKMMKDCSAGKGFDRHLLGLLLIAKEEGLPVPELFTDPLFSKS 561

  Fly  1172 ---VTFQLFTSQVATSNEGFM----AYGPLLSDGYGVCYNPKESKITFAISAWKSCKEINTIRFA 1229
               ..|.|.||.|     |::    ...|::.:|||..|:.::.:...|.||||||.|.:..:..
Human   562 GGGGNFVLSTSLV-----GYLRVQGVVVPMVHNGYGFFYHIRDDRFVVACSAWKSCPETDAEKLV 621

  Fly  1230 KAIKKSLNDMRKLI 1243
            :....:.:||.:|:
Human   622 QLTFCAFHDMIQLM 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5122	NP_609601.1	Carn_acyltransf	665..1240	CDD:279140	186/651 (29%)
CROT	NP_001137407.1	Carn_acyltransf	20..631	CDD:279140	184/641 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920