DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5122 and crata

DIOPT Version :9

Sequence 1:	NP_609601.1	Gene:	CG5122 / 34703	FlyBaseID:	FBgn0032471	Length:	1263	Species:	Drosophila melanogaster
Sequence 2:	NP_001005587.1	Gene:	crata / 449545	ZFINID:	ZDB-GENE-040927-17	Length:	631	Species:	Danio rerio

Alignment Length:	597	Identity:	220/597 - (36%)
Similarity:	337/597 - (56%)	Gaps:	31/597 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   665 LKKFPALPLKQSIASYLSSIEPFLNEEELKVEQKVAKKF--VDNEGAKLQQLLEEEAEGTDNWLT 727
            |.|.|..||||:...||::::|.::.|||...:|:.:.|  ....|.:||:.||..|...:|||:
Zfish    40 LPKLPVPPLKQTCDRYLAALDPIVDPEELNHTRKLLEDFQKPGGVGERLQKGLESRAAKLNNWLS 104

  Fly   728 PRWTRSAYLTYQAPLTVFSSPGLSFPIQEFKDTNDFLNFTAKAIYGMCEFKQLVDQNKIPVVQMG 792
            ..|.::|||.|:.|:.|.||||:..|..||.|....:.:.||.|.|:.:||.::|...:|:..:|
Zfish   105 DWWLQTAYLDYRMPVVVHSSPGVVLPRMEFSDRQGQMRYAAKLIAGVLDFKSMIDNETLPLEYLG 169

  Fly   793 KHQLDNSQFGKIFGTVRKPGRFCDTIEQY----NDADYIVVVYNNNYFKLPIYSQSGALLHAHTL 853
            ...|...|:.::..:.|.||...||:..|    ..:.:|.||:|..:|.|.:|:..|..|....:
Zfish   170 GKPLCMHQYYQVLSSCRIPGTKRDTVVNYAMDKRPSTHITVVHNFQFFVLDVYNSDGTPLTVDQI 234

  Fly   854 RDALQDILECPIKVGKH-FGLLTHDNRSNWAEAYTVLCRPHGNADTVETIEQSLFVVCLDNCVPT 917
            ...|:.|....::..|. .|:||.::|::|.:||..|.:...|.::|..|::|:|.||||  .|.
Zfish   235 YIQLEKIWNSSLQTNKEPIGILTSNHRNSWGKAYNNLIKDKTNKESVRAIQKSIFTVCLD--APM 297

  Fly   918 PKGEERIVQAH---QLLHGGGVRQNSANRWMDKTIQLIVNPNGLAGFCYEHSPADCQPLAMLMDF 979
            |:..:.:.:..   |:|||||.|.||.|||.|||:|.|:..:|..|..|||:||:..|:..::|.
Zfish   298 PRASDDMYRTRAGVQMLHGGGSRWNSGNRWFDKTLQFIIGEDGTCGLIYEHAPAEGPPIVSILDH 362

  Fly   980 VQLKVTEPNYGCEGCEADKKVTSNL--------LKFQPVNECINLWLCQARRNIQRIVSQLQMNV 1036
            |          .|..:..:.|.:.:        |:|....| |...:..|::|:..:|..|.:.|
Zfish   363 V----------VEYMKKSEMVRTPMVPLRMPQKLRFNITPE-IKKDIEDAKQNMNIMVHDLDLRV 416

  Fly  1037 INFECYGKCFIKAQGLNPDSYIQMALSLAYYSMYGKIPAQYESAHLRIFHEGRTETIRSTSNESK 1101
            ..|..:||.|.|:|.::||::|||||.||||.:|.:....||||.||:|..|||:||||.|::|.
Zfish   417 NVFTHFGKNFPKSQKMSPDAFIQMALQLAYYRIYKRCCPTYESASLRMFRLGRTDTIRSASSDSA 481

  Fly  1102 TFLLAMQSEKASMSEKLAALQKAVDAHEKLIKEAINGQGIDRHLFGLQEMALEKGMPIPEFFRSK 1166
            :|:.||.......:||:|.|.|||.||......||.||.|||||.||:..|:|....:||.|...
Zfish   482 SFVKAMDDPVKHNTEKVALLDKAVKAHRSYTDMAIRGQAIDRHLLGLKLQAIEDLAALPEIFMDT 546

  Fly  1167 GYVRSVTFQLFTSQVATSNEGFMAYGPLLSDGYGVCYNPKESKITFAISAWKSCKEINTIRFAKA 1231
            .|..::.:.|.||||....:..|.:||::.|||||||||.::.|.||:||:.||::.|.:|.|:.
Zfish   547 SYAVALHYNLSTSQVPAKTDCVMCFGPVVPDGYGVCYNPMDTHINFAVSAFNSCQDTNAVRLAQG 611

  Fly  1232 IKKSLNDMRKLI 1243
            ::.:|.|||.|:
Zfish   612 LEDALLDMRTLL 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5122	NP_609601.1	Carn_acyltransf	665..1240	CDD:279140	217/592 (37%)
crata	NP_001005587.1	Carn_acyltransf	40..620	CDD:279140	217/592 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594976
Domainoid	1	1.000	403	1.000	Domainoid score	I686
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H598
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm24513
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	O	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.850