DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5122 and CROT

DIOPT Version :9

Sequence 1:	NP_609601.1	Gene:	CG5122 / 34703	FlyBaseID:	FBgn0032471	Length:	1263	Species:	Drosophila melanogaster
Sequence 2:	NP_001334704.1	Gene:	CROT / 43332	FlyBaseID:	FBgn0039543	Length:	618	Species:	Drosophila melanogaster

Alignment Length:	623	Identity:	175/623 - (28%)
Similarity:	291/623 - (46%)	Gaps:	57/623 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   655 ANNDPNKKPELKKFPALP---LKQSIASYLSSIEPFLNEEELKVEQKVAKKFVDNEGAKLQQLLE 716
            :.:|.|.....:..|:||   |:.::..|.|.|:||..:|||...:|...:|.:..||:|.:.|:
  Fly    10 SKDDKNTFDFDETLPSLPLPELRDTMERYYSCIQPFGTKEELAQARKTIDEFQNGVGAQLHEQLK 74

  Fly   717 EEAEGTDNWLTPRWTRSAYLTYQAPLTVFSSPGLSFPIQ----EFKDTNDF-LNFTAKAIYGMCE 776
            :.|.|..|||...|....|...:.||..:..  :..|.|    ...:|.:: |...|:.|:...|
  Fly    75 KRAAGMRNWLGTWWEDYGYHLIRMPLLPYQL--MVMPSQLEMVGVPETPEYMLKSLARHIHHSLE 137

  Fly   777 FKQLVDQNKIPVVQM--GKHQLDNSQFGKIFGTVRKPGRFCDTIEQY-------NDADYIVVVYN 832
            |..|..::.|..:..  ||.:..::.:...|.|.|.||...|.||::       ....::::...
  Fly   138 FWDLTRKSSIKPLSSNGGKIKYSSALYKHFFSTCRVPGEEQDHIEKHFLTKDEGKTPSHMLISGK 202

  Fly   833 NNYFKLPIYSQSGALLHAHTLRDALQ---DILECPIKVGKHFGLLTHDNRSNWAEAYTVLCR-PH 893
            ...|......:...:|.|..:..|||   .||:.. .:|.....|:||.||.||.....|.. ..
  Fly   203 GRQFIFDCVHEDDTILSAPEILVALQRVRSILDYE-PLGDCVPTLSHDERSTWARNRNRLREISV 266

  Fly   894 GNADTVETIEQSLFVVCLDNC--VPTPKGEERIVQAHQLLHGGGVRQNSANRWMDKTIQLIVNPN 956
            .|.:|:..:|.:    |::.|  ..:||..|...|.       |:..:..:||.|::..:|...|
  Fly   267 ANKETLLLVESA----CMEICWYEQSPKDYEESCQL-------GLYGDLHSRWADRSSSIIAFRN 320

  Fly   957 GLAGFCYEHSPADCQPLAMLMDFVQ---LKVTEPNYGCEGCEADKKVTSNLLKFQPVNECINLWL 1018
            |...:..|||..|.........|:|   |:|.||::    .||:|   .|:|:.:.::..::..|
  Fly   321 GRCNWTGEHSCYDGTVSISYATFMQLSFLEVPEPDW----AEAEK---GNVLEVKELHFQLDDTL 378

  Fly  1019 CQARRNIQRIVSQLQMNV----INFECYGKCFIKAQGLNPDSYIQMALSLAYYSMYGKIPAQYES 1079
            ....:.:|:.:....::|    ..|:.|||.|:|...|:|||::|:.:..|||.|:.:|...||:
  Fly   379 KNEIKRVQKDIDDRGIDVTVTFTAFDDYGKDFMKTHRLHPDSFVQVVMQWAYYQMHKEIAPTYET 443

  Fly  1080 AHLRIFHEGRTETIRSTSNESKTFLLAMQSEKASMSEKLAALQKAVDAHEKLIKEAINGQGIDRH 1144
            |.:|.::.|||||:||.::....||.|..:::........|.::|||.|:..:.||..|.|||||
  Fly   444 ALMRQYYNGRTETLRSCTSAVAEFLRASSNKQVGDMSLARAFRRAVDEHKHFMNEARKGHGIDRH 508

  Fly  1145 LFGLQEMALEKGMPIPEFFRSKGYVRS---VTFQLFTSQVA-TSNEGFMAYGPLLSDGYGVCYNP 1205
            ||||...|.|..|.||.|:....|.:|   ..|.|.:|.:. |:|.||:|  |::.|||||.|:.
  Fly   509 LFGLWCAAYESKMDIPAFYDDPMYTKSGGGGNFVLSSSTLGFTANVGFVA--PMVFDGYGVFYSI 571

  Fly  1206 KESKITFAISAWKSCKEINTIRFAKAIKKSLNDMRKLI 1243
            ....:....:|::...:.:..:|....|.|...:..|:
  Fly   572 TSEAVFINTTAYRDSLKTSARKFNDIFKDSFRRISVLL 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5122	NP_609601.1	Carn_acyltransf	665..1240	CDD:279140	172/608 (28%)
CROT	NP_001334704.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469041
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D167256at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950