Protein Alignment CG5122 and CPT2

DIOPT Version :10

• Sequence 1: NP_609601.1
• Gene: CG5122 / 34703
• FlyBaseID: FBgn0032471
• Length: 1263
• Species: Drosophila melanogaster
• Sequence 2: NP_000089.1
• Gene: CPT2 / 1376
• HGNCID: 2330
• Length: 658
• Species: Homo sapiens
• Alignment Length: 709
• Identity: 184/709 - (25%)
• Similarity: 311/709 - (43%)
• Gaps: 129/709 - (18%)

  Fly   588 PQAPQLSP-SPSNKEIKIATVEKIKSPKPLS----KPQYSKRSNCEVKTQCAEKPQKVPKKCIKS 647
            |:.|.:.| :||               :|||    ..||.:||             .||
Human    11 PRGPAVGPGAPS---------------RPLSAGSGPGQYLQRS-------------IVP------ 41

  Fly   648 EIRHLADANNDPNKKPELKKFPALPLKQSIASYLSSIEPFLNEEELKVEQKVAKKFVDNEGAKL- 711
             ..|..|:         |.:.|...|:.:|..|||:.:|.||:.:.:..::..|.|.:..|.:|
Human    42 -TMHYQDS---------LPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELH 96

  Fly   712 QQL--LEEEAEGTDNWLTPRWTRSAYLTYQAPLTVFSSPGLSFPIQEFKDTNDFL----NFTAKA 770
            :||  |:::.:.| ::::..|. ..||:.:..:.:..:|.::|......:.||.|    |.|..|
Human    97 EQLVALDKQNKHT-SYISGPWF-DMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSA 159

  Fly   771 I-------YGMCE---------------FKQLVDQNKIP-------VVQMGKHQLDNSQFGKIFG 806
            |       .|:.|               ||:|:  ..:|       ...:..:.||.||:.::|.
Human   160 IRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLI--RFVPSSLSWYGAYLVNAYPLDMSQYFRLFN 222

  Fly   807 TVRKPGRFCDTIEQYNDADYIVVVYNNNYFKLPIYSQSGALLHAHTLRDALQDIL-------ECP 864
            :.|.|....|.:...:.|.:::|:...|::...:..|.|.::....::..|:.||       |.|
Human   223 STRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFP 287

  Fly   865 IKVGKHFGLLTHDNRSNWAEAYTVLCRPHGNADTVETIEQSLFVVCLDNCVPTPKGEERIVQAHQ 929
            :      ..||.:||..|||....| ...||.:::..::.::|.:|||: .|.   ::.:..:|.
Human   288 L------AYLTSENRDIWAELRQKL-MSSGNEESLRKVDSAVFCLCLDD-FPI---KDLVHLSHN 341

  Fly   930 LLHGGGVRQNSANRWMDKTIQLIVNPNGLAGFCYEHSPADCQPLAML-------MDFVQLKVTEP 987
            :|||.|     .|||.||:..||:..:|.....:|||..|  .:|:|       .|..|.....|
Human   342 MLHGDG-----TNRWFDKSFNLIIAKDGSTAVHFEHSWGD--GVAVLRFFNEVFKDSTQTPAVTP 399

  Fly   988 NYGCEGCEADKKVTSNLLKFQPVNECINLWLCQARRNIQRIVSQLQMNVINFECYGKCFIKAQGL 1052
            .  .:....|..||...|.|: :.:.:...:..|:......:..|.::.:.|:..||.|:|.|.|
Human   400 Q--SQPATTDSTVTVQKLNFE-LTDALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKL 461

  Fly  1053 NPDSYIQMALSLAYYSMYGKIPAQYESAHLRIFHEGRTETIRSTSNESKTFLLAMQSE--KASMS 1115
            :||:..|:|..:|:...||:..|.|||.....|..|||||||..|..:|....|...|  :.|..
Human   462 SPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKRCSEAFVREPSRHSAG 526

  Fly  1116 EKLAALQKAVDAHEKLIKEAINGQGIDRHLFGLQEMALEKGMPIPEFFRSKGYVRSVTFQLFTSQ 1180
            |....:.:....|.:|.|||..|||.|||||.|:.:|..||:.:||.:....|.:.....|.||.
Human   527 ELQQMMVECSKYHGQLTKEAAMGQGFDRHLFALRHLAAAKGIILPELYLDPAYGQINHNVLSTST 591

  Fly  1181 VATSNEGFMAYGPLLSDGYGVCYNPKESKITFAISAWKSCKEINTIRFAKAIKKSLNDM 1239
            :::.......:.|::|||:||.|...::.|...:|::..   .|...|.:.::|:|.||
Human   592 LSSPAVNLGGFAPVVSDGFGVGYAVHDNWIGCNVSSYPG---RNAREFLQCVEKALEDM 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5122	NP_609601.1	PTZ00449	<299..668	CDD:185628	17/84 (20%)
		Carn_acyltransf	672..1234	CDD:459926	162/613 (26%)
CPT2	NP_000089.1	Carn_acyltransf	52..642	CDD:459926	163/617 (26%)