DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5122 and Crat

DIOPT Version :9

Sequence 1:	NP_609601.1	Gene:	CG5122 / 34703	FlyBaseID:	FBgn0032471	Length:	1263	Species:	Drosophila melanogaster
Sequence 2:	XP_006497708.1	Gene:	Crat / 12908	MGIID:	109501	Length:	631	Species:	Mus musculus

Alignment Length:	631	Identity:	222/631 - (35%)
Similarity:	351/631 - (55%)	Gaps:	47/631 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   636 KPQKVPKKCIKSEIRHLADANNDPNKKPELKKFPALPLKQSIASYLSSIEPFLNEEELKVEQKVA 700
            ||..:.|  :....:...||         |.:.|..||:||:..||.:::|.::|||....:::.
Mouse    17 KPSSLMK--VSGRFKAHQDA---------LPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLV 70

  Fly   701 KKFVDNEGA--KLQQLLEEEAEGTDNWLTPRWTRSAYLTYQAPLTVFSSPGLSFPIQEFKDTNDF 763
            .:|..:.|.  :||:.||..|:..:|||:..|.::|||.::.|:.::||||:..|.|:|.|....
Mouse    71 DEFQTSGGVGERLQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQ 135

  Fly   764 LNFTAKAIYGMCEFKQLVDQNKIPVVQMGKHQLDNSQFGKIFGTVRKPGRFCDTIEQY----NDA 824
            |.|.||.|.|:.:||.::|...:||..:|...|..:|:.:|..:.|.||...|::..:    ...
Mouse   136 LRFAAKLIEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPP 200

  Fly   825 DYIVVVYNNNYFKLPIYSQSGALLHAHTLRDALQDILECPIKVGKH-FGLLTHDNRSNWAEAYTV 888
            .:|.||:|..:|:|.:|...|..|.:..:...|:.|....::..|. .|:||.::|:.||:||..
Mouse   201 THITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKAYNN 265

  Fly   889 LCRPHGNADTVETIEQSLFVVCLDNCVPTPKGEERIVQAH---QLLHGGGVRQNSANRWMDKTIQ 950
            |.:...|.::|.:|::|:|.||||..|  |:..:.:.:.|   |:|||||.:.||.|||.|||:|
Mouse   266 LIKDKVNRESVNSIQKSIFTVCLDKQV--PRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQ 328

  Fly   951 LIVNPNGLAGFCYEHSPADCQPLAMLMDFVQLKVTEPNYGCEGCEADKKVTSNL--------LKF 1007
            .||..:|..|..|||:.|:..|:..|:|.|.....:|          :.|.|.:        |:|
Mouse   329 FIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKP----------ELVRSPMVPLPMPKKLRF 383

  Fly  1008 QPVNECINLWLCQARRNIQRIVSQLQMNVINFECYGKCFIKAQGLNPDSYIQMALSLAYYSMYGK 1072
            ....|..| .:.:|::|:..::..|.:.::.|..:||.|.|::.|:||::||:||.||||.:||:
Mouse   384 NITPEIKN-DIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQ 447

  Fly  1073 IPAQYESAHLRIFHEGRTETIRSTSNESKTFLLAMQSEKASMSEKLAALQKAVDAHEKLI----- 1132
            ..|.||||.||:||.|||:||||.|.:|..|:..|........:|:..|:|||.||....
Mouse   448 ACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDRISH 512

  Fly  1133 KEAINGQGIDRHLFGLQEMALEKGMPIPEFFRSKGYVRSVTFQLFTSQVATSNEGFMAYGPLLSD 1197
            .:||.|:..||||.||:..|:|..:.:|:.|....|..::.|.|.||||....:..|.:||::.|
Mouse   513 PQAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVMFFGPVVPD 577

  Fly  1198 GYGVCYNPKESKITFAISAWKSCKEINTIRFAKAIKKSLNDMRKLI 1243
            |||:||||.|:.|.|::||:.||.|.|..|.|..::|:|.|||.|:
Mouse   578 GYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLL 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5122	NP_609601.1	Carn_acyltransf	665..1240	CDD:279140	214/597 (36%)
Crat	XP_006497708.1	Carn_acyltransf	35..620	CDD:376382	214/597 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849378
Domainoid	1	1.000	398	1.000	Domainoid score	I746
eggNOG	1	0.900	-	-		E1_KOG3717
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H598
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001049
OrthoInspector	1	1.000	-	-		otm43021
orthoMCL	1	0.900	-	-		OOG6_102174
Panther	1	1.100	-	-	O	PTHR22589
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X630
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.700