Protein Alignment CG5122 and Cpt2

DIOPT Version :10

• Sequence 1: NP_609601.1
• Gene: CG5122 / 34703
• FlyBaseID: FBgn0032471
• Length: 1263
• Species: Drosophila melanogaster
• Sequence 2: NP_034079.2
• Gene: Cpt2 / 12896
• MGIID: 109176
• Length: 658
• Species: Mus musculus
• Alignment Length: 631
• Identity: 167/631 - (26%)
• Similarity: 286/631 - (45%)
• Gaps: 88/631 - (13%)

  Fly   665 LKKFPALPLKQSIASYLSSIEPFLNEEELKVEQKVAKKFVDNEGAKLQQ--LLEEEAEGTDNWLT 727
            |.:.|...|:.::..|||:.:|.||:.:.:..:.:.|.|.:..|.:|..  |.:::.....::::
Mouse    49 LPRLPIPKLEDTMKRYLSAQKPLLNDSQFRKTEVLCKDFENGIGKELHAHLLAQDKQNKHTSYIS 113

  Fly   728 PRWTRSAYLTYQAPLTVFSSPGLSFPIQEFKDTNDFL----NFTAKAI-------YGMCE----- 776
            ..|. ..|||.:..:.:..:|.::|......:.||.|    |.|..|:       .|:.|
Mouse   114 GPWF-DMYLTARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKTLRAGLLEPEVFH 177

  Fly   777 ----------FKQLVDQNKIP-------VVQMGKHQLDNSQFGKIFGTVR--KPGR---FCDTIE 819
                      ||:|:  ..:|       ...:..:.||.||:.::|.:.|  ||.|   |.||
Mouse   178 LNPARSDTDAFKRLI--RFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRIPKPSRDELFTDT-- 238

  Fly   820 QYNDADYIVVVYNNNYFKLPIYSQSGALLHAHTLRDALQDIL-------ECPIKVGKHFGLLTHD 877
               .|.:::|:...:::...:..|.|.:::...::..|:.||       |.|:      ..||.:
Mouse   239 ---KARHLLVLRKGHFYVFDVLDQDGNIVNPSEIQAHLKYILSDSSPVPEFPL------AYLTSE 294

  Fly   878 NRSNWAEAYTVLCRPHGNADTVETIEQSLFVVCLDNCVPTPKGEERIVQAHQLLHGGGVRQNSAN 942
            ||..|||....|.. .||.:|:..::.::|.:|||: .|.   ::.:..:|.:|||.|     .|
Mouse   295 NRDVWAELRQKLIH-GGNEETLRKVDSAVFCLCLDD-FPM---KDLVHLSHTMLHGDG-----TN 349

  Fly   943 RWMDKTIQLIVNPNGLAGFCYEHSPADCQPLAML-------MDFVQLKVTEPNYGCEGCEADKKV 1000
            ||.||:..|||..:|.|...:||:..|  .:|:|       .|..|.....|.  .:....|..|
Mouse   350 RWFDKSFNLIVAKDGTAAVHFEHAWGD--GVAVLRFFNEVFRDSTQTPAIAPQ--SQPAATDSSV 410

  Fly  1001 TSNLLKFQPVNECINLWLCQARRNIQRIVSQLQMNVINFECYGKCFIKAQGLNPDSYIQMALSLA 1065
            :...|.|: ::..:...:..|:......:..|.::.|.|:..||.|:|.:.|:||:..|:|..:|
Mouse   411 SVQKLSFK-LSSALKAGVTAAKEKFDATMKTLTIDAIQFQRGGKEFLKKKKLSPDAVAQLAFQMA 474

  Fly  1066 YYSMYGKIPAQYESAHLRIFHEGRTETIRSTSNESKTFLLAMQSE--KASMSEKLAALQKAVDAH 1128
            :...||:..|.|||.....|..|||||||..|..:|....|...|  |.|:.|....:.:....|
Mouse   475 FLRQYGQTVATYESCSTAAFKHGRTETIRPASIFTKRCSEAFVREPSKHSVGELQHMMAECSKYH 539

  Fly  1129 EKLIKEAINGQGIDRHLFGLQEMALEKGMPIPEFFRSKGYVRSVTFQLFTSQVATSNEGFMAYGP 1193
            .:|.|||..|||.|||||.|:.:|..:|:.:||.::...|.|.....|.||.:::.......:.|
Mouse   540 GQLTKEAAMGQGFDRHLFALRYLAAARGVTLPELYQDPAYQRINHNILSTSTLSSPAVSLGGFAP 604

  Fly  1194 LLSDGYGVCYNPKESKITFAISAWKSCKEINTIRFAKAIKKSLNDM 1239
            ::.||:|:.|...:..|...:|::..   .|...|...::|.|.||
Mouse   605 VVPDGFGIAYAVHDDWIGCNVSSYSG---RNAREFLHCVQKCLEDM 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5122	NP_609601.1	PTZ00449	<299..668	CDD:185628	1/2 (50%)
		Carn_acyltransf	672..1234	CDD:459926	161/617 (26%)
Cpt2	NP_034079.2	Carn_acyltransf	52..642	CDD:459926	162/621 (26%)